Brain disorders Clinical Trials in Cincinnati, OH
As of June 2026, 45 paid clinical trials are recruiting for Brain disorders in Cincinnati, Ohio. Brain disorder trials span neurodegenerative diseases, stroke, traumatic brain injury, and neuromuscular conditions — testing both pharmacologic and rehabilitative approaches to slow progression and improve function. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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45 clinical trials for Brain disorders
·Clear filters·↓ Download CSVA Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury
Telerehabilitation In The Home After Stroke
An Examination of Whether Infrared Light Therapy Can Reduce Stress in People With Epilepsy
A Study to Evaluate the SENSE Device's Ability to Detect TBI
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2
A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease
A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease
A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis
StrokeNet Thrombectomy Endovascular Platform
Genetic and Environmental Risk Factors for Hemorrhagic Stroke
Post-Stroke Sensory Reweighting on Walking and Balance Outcomes
Optimizing CNS DHA Delivery in Elderly Adults at Risk for Dementia
Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury
A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)
A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)
Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)
A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)
Strategy for Improving Stroke Treatment Response
HIT-Stroke Trial 2
The Fourth Left Atrial Appendage Occlusion Study
Treatment With Endovascular Intervention for STroke Patients With Existing Disability
K01 Impacts of Lingual Endurance Exercise
REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study
Setting Families on a Positive Path to Recovery After Pediatric TBI: Road-to-Recovery
Improving Neurotrauma by Depolarization Inhibition With Combination Therapy (INDICT)
Pediatric Dose Optimization for Seizures in Emergency Medical Services
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
The CONFORM Pivotal Trial
ESIS in Pediatric DRE
Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study
Study in Parkinson Disease of Exercise
A Study to Investigate the Safety, Tolerability, and Processing by the Body of Intravenous and Subcutaneous RO7121932 Administration in Participants With Multiple Sclerosis
A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis
Trial-Ready Cohort-Down Syndrome (TRC-DS)
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
Parkinson's Foundation PD GENEration Genetic Registry
ROSE-Longitudinal Assessment With Neuroimaging
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
About research studies in Cincinnati
Cincinnati has approximately 1,156 recruiting research studies across a wide range of therapeutic areas. Ohio is home to The Ohio State University Wexner Medical Center, Cleveland Clinic, Cincinnati Children's, and University Hospitals Cleveland Medical Center — collectively running clinical trials across every major therapeutic area.
Top Research Study Locations in Cincinnati
Researchers run research studies in Cincinnati, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cincinnati Children's Hospital Medical Center | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, Neuroblastoma | 285 |
| University of Cincinnati | Stroke, Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia | 117 |
| University of Cincinnati Medical Center | Advanced Solid Tumor, Endometrial Cancer, Interstitial Lung Disease | 71 |
| University of Cincinnati Cancer Center-UC Medical Center | Metastatic Malignant Neoplasm in the Brain, Stage IV Lung Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8 | 55 |
| Good Samaritan Hospital - Cincinnati | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Malignant Solid Neoplasm | 48 |
| Cincinnati Children's Hospital | Amblyopia, Musculoskeletal Pain, Acute Kidney Injury | 46 |
| Bethesda North Hospital | Stage IIIB Lung Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 45 |
| The Christ Hospital | Tricuspid Regurgitation, Aortic Valve Stenosis, Heart Failure | 38 |
| TriHealth Cancer Institute-Anderson | Stage IIIB Lung Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 38 |
| TriHealth Cancer Institute-Westside | Stage IIIB Lung Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 38 |
| Oncology Hematology Care Inc-Kenwood | Stage IIIB Lung Cancer AJCC v8, Advanced Lung Non-Small Cell Carcinoma, Anatomic Stage IV Breast Cancer AJCC v8 | 30 |
| Oncology Hematology Care | Multiple Myeloma, Breast Cancer, Acute Myeloid Leukemia (AML) | 17 |
| Cincinnati Eye Institute | Cone Rod Dystrophy, Juvenile Macular Degeneration, Stargardt Disease | 14 |
| CTI Clinical Research Center | Obesity, Overweight, Obstructive Sleep Apnea | 13 |
| University of Cincinnati Cancer Center | Colorectal Cancer, Advanced Solid Tumor, Anaplastic Lymphoma Kinase-positive | 10 |
| Cincinnati Childrens Hospital Medical Center | Adrenal Insufficiency, Alopecia, Areata Alopecia | 9 |
| GSK Investigational Site | HIV Infections, Asthma, Chickenpox | 8 |
| Good Samaritan Hospital | Atrial Fibrillation, Chronic Subdural Hematoma, Deep Vein Thrombosis | 8 |
| University of Cincinnati College of Medicine | Acetabular Fracture, Adolescents, Atrial Fibrillation | 8 |
| Oncology Hematology Care Clinical Trials, LLC | Multiple Myeloma, Carcinoma, Non-Small-Cell Lung, Chronic Graft-Versus-Host Disease (cGVHD) | 6 |
| The Christ Hospital Cancer Center | Non-small Cell Lung Cancer, Advanced Adenocarcinoma, Bladder Carcinoma | 6 |
| Children's Hospital Medical Center | Biliary Atresia, Duchenne Muscular Dystrophy, Essential Fatty Acid Deficiency | 5 |
| Christ Hospital | Cardiovascular Diseases, Coronary Artery Disease, Coronary Artery Disease (CAD) | 5 |
| The Lindner Research Center | Aortic Aneurysm, Aortic Dissection, Cardiovascular Disease With Mention of Arteriosclerosis | 5 |
| Oncology Hematology Care Clinical Trials | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 4 |
Active & Upcoming Studies in Cincinnati (2026)
Recruiting trials in Cincinnati grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (322 active studies)
- Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia · Phase 2 · SWOG Cancer Research Network
- Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations · Phase 3 · SWOG Cancer Research Network
Cardiovascular (89 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Neurology & pain (82 active studies)
- The BRIDGE Pain Study · Children's Hospital Medical Center, Cincinnati
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
Pediatric (35 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- Asthma Ctrl SMART Trial · Children's Hospital Medical Center, Cincinnati
Diabetes & metabolic (31 active studies)
- GLP-1 RA for Stage 1 Type 1 Diabetes · Phase 2 · Children's Hospital Medical Center, Cincinnati
- A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight · Phase 2 · Eli Lilly and Company
Mental health & behavior (25 active studies)
- ALTO-207 in Adults With Treatment-resistant Depression (TRD) · Phase 2 · Alto Neuroscience
- A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Eye & vision (12 active studies)
- Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants · Phase 4 · Neurotech Pharmaceuticals
- Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB) · Phase 1, Phase 2 · Opus Genetics, Inc
Vaccines (8 active studies)
- A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza · Phase 3 · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
HIV / STI (8 active studies)
- Health-E You Efficacy Trial for Male Adolescents · Johns Hopkins University
- Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV · Phase 2 · National Institute of Allergy and Infectious Diseases (NIAID)
Common conditions studied in Cincinnati
- Heart Failure (20 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Multiple Myeloma (12 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Solid Tumor (11 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Breast Cancer (11 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Cystic Fibrosis (11 active studies). Recruiting Cystic Fibrosis studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Obesity (11 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
Leading research sponsors in Cincinnati
- Children's Hospital Medical Center, Cincinnati
- National Cancer Institute (NCI)
- University of Cincinnati
- AstraZeneca
- Children's Oncology Group
Local regulations and guidelines
Clinical trials in Ohio are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Ohio research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Cincinnati. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Cincinnati
Hipa.ai aggregates every recruiting study in Cincinnati from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Cincinnati?
There are approximately 1,156 recruiting clinical trials in Cincinnati, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Cincinnati pay participants?
Most recruiting trials in Cincinnati compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Cincinnati?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Cincinnati?
The most common conditions under active study in Cincinnati include Heart Failure (20), Multiple Myeloma (12), Advanced Solid Tumor (11), Breast Cancer (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Cincinnati?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Cincinnati on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Cincinnati?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Cincinnati?
Recruiting research sites in Cincinnati include Cincinnati Children's Hospital Medical Center, University of Cincinnati, University of Cincinnati Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Cincinnati right now?
The largest active categories in Cincinnati are Cancer & tumors (322), Cardiovascular (89), Neurology & pain (82). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.