Solid tumor Clinical Trials in Cincinnati, OH
As of June 2026, 31 paid clinical trials are recruiting for Solid tumor in Cincinnati, Ohio. Recruiting Solid tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Cincinnati
Filter results
31 clinical trials for Solid tumor
·Clear filters·↓ Download CSVTesting Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
Study of SGR-3515 In Participants With Advanced Solid Tumors.
A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors
A Phase I Study to Evaluate the Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors
FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors
A Study of LM-24C5 For Advanced Solid Tumors
Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers
Pan-RAS Inhibitor YL-17231 in Patients With Advanced Solid Tumors Harboring Mutations in KRAS, HRAS, or NRAS
A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer
Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
A Study of DB-1310 in Advanced/Metastatic Solid Tumors
A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors
Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy
VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
A Study of PYX-201 in Advanced Solid Tumors
Study of SGN1 in Patients With Advanced Solid Tumor
Study of CHS-114 in Participants With Advanced Solid Tumors
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer
A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers
A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
Project: Every Child for Younger Patients With Cancer
About research studies in Cincinnati
Cincinnati has approximately 1,160 recruiting research studies across a wide range of therapeutic areas. Ohio is home to The Ohio State University Wexner Medical Center, Cleveland Clinic, Cincinnati Children's, and University Hospitals Cleveland Medical Center — collectively running clinical trials across every major therapeutic area.
Top Research Study Locations in Cincinnati
Researchers run research studies in Cincinnati, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cincinnati Children's Hospital Medical Center | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, Neuroblastoma | 288 |
| University of Cincinnati | Stroke, Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia | 117 |
| University of Cincinnati Medical Center | Advanced Solid Tumor, Endometrial Cancer, Interstitial Lung Disease | 72 |
| University of Cincinnati Cancer Center-UC Medical Center | Metastatic Malignant Neoplasm in the Brain, Stage IV Lung Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8 | 57 |
| Good Samaritan Hospital - Cincinnati | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Malignant Solid Neoplasm | 48 |
| Bethesda North Hospital | Stage IIIB Lung Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 46 |
| Cincinnati Children's Hospital | Amblyopia, Musculoskeletal Pain, Acute Kidney Injury | 46 |
| TriHealth Cancer Institute-Anderson | Stage IIIB Lung Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 39 |
| TriHealth Cancer Institute-Westside | Stage IIIB Lung Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 39 |
| The Christ Hospital | Tricuspid Regurgitation, Aortic Valve Stenosis, Heart Failure | 38 |
| Oncology Hematology Care Inc-Kenwood | Stage IIIB Lung Cancer AJCC v8, Advanced Lung Non-Small Cell Carcinoma, Anatomic Stage IV Breast Cancer AJCC v8 | 30 |
| Oncology Hematology Care | Multiple Myeloma, Breast Cancer, Acute Myeloid Leukemia (AML) | 17 |
| Cincinnati Eye Institute | Cone Rod Dystrophy, Juvenile Macular Degeneration, Stargardt Disease | 14 |
| CTI Clinical Research Center | Obesity, Overweight, Obstructive Sleep Apnea | 13 |
| University of Cincinnati Cancer Center | Colorectal Cancer, Advanced Solid Tumor, Anaplastic Lymphoma Kinase-positive | 10 |
| Cincinnati Childrens Hospital Medical Center | Adrenal Insufficiency, Alopecia, Areata Alopecia | 8 |
| GSK Investigational Site | HIV Infections, Asthma, Chickenpox | 8 |
| Good Samaritan Hospital | Atrial Fibrillation, Chronic Subdural Hematoma, Deep Vein Thrombosis | 8 |
| University of Cincinnati College of Medicine | Acetabular Fracture, Adolescents, Atrial Fibrillation | 8 |
| Oncology Hematology Care Clinical Trials, LLC | Multiple Myeloma, Carcinoma, Non-Small-Cell Lung, Chronic Graft-Versus-Host Disease (cGVHD) | 6 |
| The Christ Hospital Cancer Center | Non-small Cell Lung Cancer, Advanced Adenocarcinoma, Bladder Carcinoma | 6 |
| Children's Hospital Medical Center | Biliary Atresia, Duchenne Muscular Dystrophy, Essential Fatty Acid Deficiency | 5 |
| Christ Hospital | Cardiovascular Diseases, Coronary Artery Disease, Coronary Artery Disease (CAD) | 5 |
| The Lindner Research Center | Aortic Aneurysm, Aortic Dissection, Cardiovascular Disease With Mention of Arteriosclerosis | 5 |
| Oncology Hematology Care Clinical Trials | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 4 |
Active & Upcoming Studies in Cincinnati (2026)
Recruiting trials in Cincinnati grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (325 active studies)
- Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia · Phase 2 · SWOG Cancer Research Network
- Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer · Phase 2, Phase 3 · Pfizer
Cardiovascular (89 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Neurology & pain (81 active studies)
- The BRIDGE Pain Study · Children's Hospital Medical Center, Cincinnati
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
Pediatric (35 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- Asthma Ctrl SMART Trial · Children's Hospital Medical Center, Cincinnati
Diabetes & metabolic (30 active studies)
- GLP-1 RA for Stage 1 Type 1 Diabetes · Phase 2 · Children's Hospital Medical Center, Cincinnati
- A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight · Phase 2 · Eli Lilly and Company
Mental health & behavior (25 active studies)
- ALTO-207 in Adults With Treatment-resistant Depression (TRD) · Phase 2 · Alto Neuroscience
- A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Eye & vision (12 active studies)
- Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants · Phase 4 · Neurotech Pharmaceuticals
- Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB) · Phase 1, Phase 2 · Opus Genetics, Inc
Vaccines (8 active studies)
- A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza · Phase 3 · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
HIV / STI (8 active studies)
- Health-E You Efficacy Trial for Male Adolescents · Johns Hopkins University
- Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV · Phase 2 · National Institute of Allergy and Infectious Diseases (NIAID)
Common conditions studied in Cincinnati
- Heart Failure (20 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Breast Cancer (12 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Multiple Myeloma (12 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Solid Tumor (11 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Cystic Fibrosis (11 active studies). Recruiting Cystic Fibrosis studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Obesity (11 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
Leading research sponsors in Cincinnati
- Children's Hospital Medical Center, Cincinnati
- National Cancer Institute (NCI)
- University of Cincinnati
- AstraZeneca
- Children's Oncology Group
Local regulations and guidelines
Clinical trials in Ohio are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Ohio research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Cincinnati. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Cincinnati
Hipa.ai aggregates every recruiting study in Cincinnati from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Cincinnati?
There are approximately 1,160 recruiting clinical trials in Cincinnati, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Cincinnati pay participants?
Most recruiting trials in Cincinnati compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Cincinnati?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Cincinnati?
The most common conditions under active study in Cincinnati include Heart Failure (20), Breast Cancer (12), Multiple Myeloma (12), Advanced Solid Tumor (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Cincinnati?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Cincinnati on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Cincinnati?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Cincinnati?
Recruiting research sites in Cincinnati include Cincinnati Children's Hospital Medical Center, University of Cincinnati, University of Cincinnati Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Cincinnati right now?
The largest active categories in Cincinnati are Cancer & tumors (325), Cardiovascular (89), Neurology & pain (81). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.