Lyme Disease — Trials, FDA Actions & Pivotal Research

15 active Lyme Disease trials currently recruiting in the US, sourced from ClinicalTrials.gov.

Synced daily from openFDA and ClinicalTrials.gov. Last sync: June 12, 2026.

Recruiting trials by city

Cities where Lyme Disease trials in our archive had recruiting sites. Each link lists every currently recruiting paid clinical trial at that location.

Deerfield Beach, FL

Active Lyme Disease trials

Currently recruiting US trials matching Lyme Disease, sourced live from ClinicalTrials.gov. We’ll add per-event articles here as those trials post results or hit primary completion.

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1982 to Prevent Lyme Disease in Healthy Participants (18 to 70 Years of Age)

for Lyme Disease

Sponsor: ModernaTX, Inc.

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07561294·Phase 2·Recruiting

Apply to this trial

A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine

for Lyme Disease

19 locations incl. Bangor

Sponsor: Pfizer

Sex: All·Age: 7+·Accepts healthy volunteers

Code: NCT07500506·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate Safety and Efficacy of TP-05 in Healthy Participants With Tick Exposure

for Lyme Disease

19 locations incl. Pikesville

Sponsor: Tarsus Pharmaceuticals, Inc.

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07562087·Phase 2·Recruiting

Apply to this trial

Safety and Effectiveness of the BlinkER System in Participants With Facial Nerve Palsy

for Bell's Palsy

1 location in Deerfield Beach

Sponsor: Neurotrigger Ltd

Sex: All·Age: 22 - 120

Code: NCT06542289·Not Yet Recruiting

Serological Measurement of Montpellier Professionals' Contacts with Infectious Agents Responsible for Animal-borne Diseases

for Leishmaniasis

Sponsor: University Hospital, Montpellier

Sex: All·Age: 18+

Code: NCT06859619·Not Yet Recruiting

Borrelia B-cell Diagnostics

for Lyme Disease

Sponsor: University Children's Hospital, Zurich

Sex: All·Age: 1 Month - 17·Accepts healthy volunteers

Code: NCT06045416·Recruiting

Apply to this trial

Navigating Pregnancy and Parenthood With Lyme Disease

for Lyme Disease

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: Female·Age: 18+

Code: NCT06397794·Recruiting

Apply to this trial

Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure

for Lyme Disease

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 18+

Code: NCT06026969·Recruiting

Apply to this trial

Human Immune Response to Ixodes Scapularis Tick Bites

for Tick-borne Diseases

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT05036707·Phase 1, Phase 2·Recruiting

Apply to this trial

Quest to Analyze One Thousand Humans Meditating

for Amyotrophic Lateral Sclerosis (ALS)

1 location in Palm Desert

Sponsor: Tobias Moeller-Bertram

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06583395·Enrolling By Invitation

Rheumatology Patient Registry and Biorepository

for Rheumatic Diseases

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT04402086·Recruiting

Apply to this trial

Central Nervous System Infections in Denmark

for Central Nervous System Infections

Sponsor: Aalborg University Hospital

Sex: All·Age: 18+

Code: NCT03418441·Recruiting

Apply to this trial

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

for Rare Disorders

1 location in Sioux Falls

Sponsor: Sanford Health

Sex: All·Age: All ages

Code: NCT01793168·Recruiting

Apply to this trial

Evaluation, Treatment, and Follow-up of Patients With Lyme Disease

for Lyme Disease

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 2 - 99

Code: NCT00028080·Recruiting

Apply to this trial

A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients With Suspected Post Treatment Lyme Disease Syndrome and Selected Control Populations

for Lyme Disease

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 13 - 99·Accepts healthy volunteers

Code: NCT00001539·Recruiting

Apply to this trial