Scleroderma — Trials, FDA Actions & Pivotal Research

20 active Scleroderma trials currently recruiting in the US, sourced from ClinicalTrials.gov.

Synced daily from openFDA and ClinicalTrials.gov. Last sync: June 12, 2026.

Recruiting trials by city

Cities where Scleroderma trials in our archive had recruiting sites. Each link lists every currently recruiting paid clinical trial at that location.

Ann Arbor, MI Birmingham, AL Orange, CA Aurora, CO Duarte, CA La Jolla, CA Murray, UT Orlando, FL Redwood City, CA San Francisco, CA

Active Scleroderma trials

Currently recruiting US trials matching Scleroderma, sourced live from ClinicalTrials.gov. We’ll add per-event articles here as those trials post results or hit primary completion.

Catestatin as a Novel Biomarker for Cardiovascular and Microvascular Involvement in Systemic Sclerosis

for Systemic Sclerosis

Sponsor: Assiut University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07209644·Not Yet Recruiting

A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis

for Systemic Sclerosis

30 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07497087·Phase 3·Not Yet Recruiting

A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis

for Systemic Sclerosis

16 locations incl. Scottsdale

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 16+

Code: NCT07335562·Phase 3·Recruiting

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Exploratory Clinical Study of Anti-CD19/BCMA Universal CAR-T Cell Injection for the Treatment of Refractory Autoimmune Diseases

for Rheumatoid Arthritis

Sponsor: The First Affiliated Hospital with Nanjing Medical University

Sex: All·Age: 18 - 70

Code: NCT07558850·Recruiting

Apply to this trial

Immun4Cure Cohort of Autoimmune Diseases

for Rheumatoid Arthritis

Sponsor: University Hospital, Montpellier

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07515638·Not Yet Recruiting

CD19/BCMA-Targeted Universal CAR-T Cell Injection for the Treatment of Autoimmune Diseases

for SLE - Systemic Lupus Erythematosus

Sponsor: Nanjing Bioheng Biotech Co., Ltd.

Sex: All·Age: 18 - 70

Code: NCT07596680·EARLY_Phase 1·Not Yet Recruiting

Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases

for Systemic Lupus Erythematosus

1 location in Philadelphia

Sponsor: Stephan Grupp MD PhD

Sex: All·Age: 8 - 25

Code: NCT05029336·Phase 2·Recruiting

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Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH.

for Refractory Lupus Nephritis

Sponsor: Beijing GoBroad Hospital

Sex: All·Age: 6 - 65

Code: NCT06947473·Phase 1, Phase 2·Recruiting

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Clinical Study of EVM18001 in the Treatment of Refractory Autoimmune Diseases

for System Lupus Erythematosus(SLE)

Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Sex: All·Age: 18 - 70

Code: NCT07470151·Recruiting

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A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune Diseases

for Healthy

Sponsor: Xencor, Inc.

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07284797·Phase 1·Recruiting

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A Study of Nemolizumab for the Treatment of Adults With Systemic Sclerosis

for Systemic Sclerosis

2 locations incl. Ann Arbor

Sponsor: Galderma R&D

Sex: All·Age: 18+

Code: NCT07047690·Phase 2·Recruiting

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Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Changhai Hospital

Sex: All·Age: 18 - 70

Code: NCT07246096·EARLY_Phase 1·Recruiting

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A Study of CD19 UCAR-T Cells in Subjects With Autoimmune Diseases

for Systemic Lupus Erythematosus

Sponsor: Institute of Hematology & Blood Diseases Hospital, China

Sex: All·Age: 18 - 65

Code: NCT07212322·Not Yet Recruiting

Transcriptomic Study of Cutaneous Fibroblasts in Scleroderma

for Scleroderma

Sponsor: Centre Hospitalier Universitaire Dijon

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07256418·Recruiting

Apply to this trial

A Study of AZD0120 in Autoimmune Diseases

for Systemic Sclerosis

8 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT07295847·Phase 1·Recruiting

Apply to this trial

Evaluating Tools to Communicate Scleroderma Research Results to Patients - Trial #1

for Scleroderma

Sponsor: Lady Davis Institute

Sex: All·Age: 18+

Code: NCT06373263·Not Yet Recruiting

Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach in Children and Adults Diagnosed With Scleroderma

for Scleroderma

Sponsor: Hacettepe University

Sex: All·Age: 7+

Code: NCT07292961·Recruiting

Apply to this trial

EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases

for Myocarditis

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18+

Code: NCT07077304·Recruiting

Apply to this trial

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

for Systemic Lupus Erythematosus (With and Without Nephritis)

12 locations incl. Phoenix

Sponsor: Allogene Therapeutics

Sex: All·Age: 18 - 69

Code: NCT07085104·Phase 1·Recruiting

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Exploratory Clinical Study on YTS109 Cell Therapy for Autoimmune Diseases

for Systemic Lupus Erythematosus (SLE)

Sponsor: China Immunotech (Beijing) Biotechnology Co., Ltd.

Sex: All·Age: 18 - 65

Code: NCT07236801·Phase 1·Recruiting

Apply to this trial