Depression — Trials, FDA Actions & Pivotal Research
88 updates aggregated from openFDA and ClinicalTrials.gov, covering trial milestones, FDA actions, and pivotal publications about Depression.
Synced daily from openFDA and ClinicalTrials.gov. Last sync: .
Drugs with Depression trials
Recruiting trials by city
Cities where Depression trials in our archive had recruiting sites. Each link lists every currently recruiting paid clinical trial at that location.
Updates
2026
- Results postedHome-Based Walking Program Reduces Depression Scores in Heart Failure Patients· May 12, 2026
- Results postedDepression: Magnetic Seizure Therapy Shows Memory Benefit Over ECT· May 11, 2026
- Results postedACT Improves Post-Surgical Function and Pain in Veterans· May 6, 2026
- Results postedDepression: Outreach Messaging Increases Treatment Initiation in Study· May 1, 2026
- Results postedDepression: Cognitive Fitness Shows Mixed Results in Older Adults· Apr 29, 2026
- Results postedDepression: Game-Based Digital Therapeutic MEL-T01 Reduces PHQ-9 Scores· Apr 29, 2026
- Results postedFirearm Storage Decision Tool Pilot Study Results for Depression Posted· Apr 28, 2026
- Results postedColorectal Cancer: Physical Activity Program Improves Survival· Apr 24, 2026
- Results postedDepression: Home tDCS Active Stimulation Not Superior to Sham in Empower Trial· Apr 22, 2026
- Results postedBE-SMART-DR Intervention Shows Reduced Suicidal Ideation in Adolescents· Apr 13, 2026
- Results postedDepression: Bundled Intervention Reduces Symptoms in Older Cardiac Patients· Apr 9, 2026
- Results postedDepression: Bundled Intervention Reduces Symptoms in Orthopedic Surgery Patients· Apr 9, 2026
- Results postedDepression: Mindfulness Intervention Trial Posts Feasibility Results· Apr 2, 2026
- Results postedDepression: Behavioral Activation Bundle Shows Lower PHQ-ADS Scores· Mar 31, 2026
- Results postedDepression: Positive Minds-Strong Bodies Enhanced Shows Improved Symptoms· Mar 30, 2026
- Results postedTransdiagnostic Therapy for Depression, OCD, GAD: No Significant Differences· Mar 10, 2026
- Results postedNeurofeedback for Depression Reduces Suicide Severity and Ideation· Mar 3, 2026
- Results postedBipolar Disorder: CBTpro Trial Results Posted for Psychosis Training Tool· Feb 27, 2026
- Results postedDepression: TAU Shows Greater PHQ-A Score Reduction in Adolescent Trial· Feb 27, 2026
- Results postedeScreening Boosts Depression, PTSD, Suicide Screening Rates· Feb 17, 2026
- Results postedDepression: Digital Mental Health Service Trial Results Posted· Feb 9, 2026
- Results postedDepression: Behavioral Activation Prenatal Trial Posts Key Results· Feb 5, 2026
- Results postedDepression Prevention Trial Shows Reduced Symptom Burden in Older Bereaved…· Jan 28, 2026
- Results postedDepression: Virtual Mindfulness Intervention Shows Lower PHQ Score· Jan 28, 2026
- Results postedCare Coordination Trial for Post-Preterm Birth Women Posts Feasibility Results· Jan 27, 2026
- Results postedParenting Skills Intervention Shows Higher Mean Scores in OUD Context· Jan 27, 2026
- Results postedDepression Trial Reports 7.1-Point MADRS Score Change (p=0.05)· Jan 26, 2026
- Results postedBrexanolone Study for Perimenopausal Depression Terminated Early· Jan 22, 2026· drug: Brexanolone
- Results postedDepression Study: SOVA Peer Ambassador Program Shows Low Feasibility· Jan 16, 2026
- Results postedAdhere.ly-Enhanced Therapy Shows Mixed Results in Depression and Anxiety Trial· Jan 15, 2026
2025
- Results postedDepression: Intervention Reduces Caregiver Depression and Burden· Dec 18, 2025
- Results postedPerinatal Depression: Chronotherapy Shows Greater Symptom Change· Dec 9, 2025
- Results postedDepression: Exercise Reduced Scores in Hemodialysis Patients· Dec 8, 2025
- Results postedDepression: TERTULIAS Peer Support Groups Reduce Symptoms, Boost Resilience· Dec 1, 2025
- Results postedDepression eHealth Intervention: Results Posted for Veteran Engagement Study· Nov 21, 2025
- Results postedDepression: Neurofeedback Study Shows Change in Attention, Not Mood· Nov 13, 2025
- Results postedDepression Trial Results Posted for BE WITH Project· Nov 12, 2025
- Results postedDepression, PTSD: Transdiagnostic vs. Disorder-Specific Therapy Results Posted· Nov 6, 2025
- Results postedDepression: Digital Intervention Shows Greater Mean Symptom Reduction in OUD…· Nov 5, 2025
- Results postedDepression: Feasibility Trial Results for Psychosocial Intervention Posted· Nov 3, 2025
- Results postedMobile App for Student Veterans' Academic Success: Usability Results Posted· Oct 31, 2025
- Results postedDepression: Message-Based Psychotherapy Trial Results Posted· Oct 30, 2025
- Results postedDepression: Hyperthermia + CBT Shows Symptom Reduction, Similar to Sham· Oct 30, 2025
- Results postedDepression: iCBT and TMS vs. Psychoeducation and TMS Trial Results Posted· Oct 29, 2025
- Results postedDepression: CBT Mobile App Augmentation Shows Higher PHQ-9 Least Squares Mean· Oct 27, 2025
- Results postedOnline Help-Seeking Tools for SGMY with Depression Show Feasibility; One…· Oct 21, 2025
- Results postedDepression: Sleep Intervention Reduces Amygdala Reactivity to Conscious Fear· Oct 15, 2025
- Results postedTHRIVE Intervention Pilot Results Posted for HIV Care Retention· Oct 14, 2025
- Results postedDepression: One-day Life Skills Workshop Results Posted for Veterans· Oct 8, 2025
- Results postedDepression Screening Rates Increase in HIV Primary Care Study· Oct 7, 2025
- Results postedAcupressure Trial Shows Significant Reduction in Nurses' Depressive Symptoms· Oct 6, 2025
- Results postedDepression: Pilot Study Shows Reduction in Positive Scores at 9 Months· Sep 22, 2025
- Results postedBehavioral Activation-Rehabilitation for Depression: Feasibility Results Posted· Sep 19, 2025
- Results postedDepression: Mental Health Support Trial Shows Reduced Severity· Sep 16, 2025
- Results postedDepression: MCI + IPT-A Shows Lower Scores on CES-D and HAM-D Scales· Sep 15, 2025
- Results postedDepression: Technology Enabled Service shows lower anxiety, higher engagement· Sep 12, 2025
- Results postedDepression: tDCS trial results posted, showing no significant difference· Sep 11, 2025
- Results postedCOVID-19 Digital Interventions Show Modest Impact on Vaccination Uptake· Sep 11, 2025
- Results postedDepression & Anxiety: Culturally Adapted Program Feasibility Results Posted· Sep 4, 2025
- Results postedDepression: EEG Synchronized TMS Trial Shows No Significant Remission Rate…· Aug 14, 2025
- Results postedDepression: PATH-MCI and Supportive Therapy Show Similar Cognitive Outcomes· Aug 12, 2025
- Results postedDepression: eCOT-NS Shows Greater Reduction in Symptoms Than Sham· Aug 12, 2025
- Results postedBipolar Disorder: Contingency Management Shows Similar Alcohol Outcomes· Aug 11, 2025
- Results postedDepression: Healthy Minds Program App Associated with Lower PHQ-8 Scores· Aug 1, 2025
- Primary completionDepression: INCREM Program Phase 3 Trial Reaches Primary Completion· Jul 31, 2025
- Results postedDepression: Intensive tDCS Feasibility Study Reports Symptom Reduction· Jul 28, 2025
- Results postedCognitive Training Improves Performance in Depression, Anxiety, PTSD Trial· Jul 23, 2025
- Results postedDepression: SSAGE trial results posted for DSM-5 symptom counts· Jul 20, 2025
- Results postedRural Dementia Caregiver Project Posts Depression, Stress Outcomes· Jul 17, 2025
- Results postedDepression: Pharmacogenetic Testing Trial Shows Remission Differences· Jun 29, 2025
- Results postedDepression: Prenatal Bonding Intervention Improves Mood and Maternal Bonding· Jun 25, 2025
- Results postedDepression: Cognitive Training Video Game Shows Symptom Changes in Youth· Jun 18, 2025
- Results postedsTMS for Depression and PTSD: PCL-5 Scores Similar Between Active and Sham· Jun 17, 2025
- Results postedCAPABLE Intervention Reduces Depression Scores in Formerly Homeless Adults· Jun 15, 2025
- Results postedDepression: NeuroStar TMS Shows Similar HAMD24 Reduction to Sham· Jun 12, 2025
- Results postedDepression & Pain: Coaching and Decision Aid Improves PHQ-8, BPI Scores· Jun 11, 2025
- Results postedUnified Protocol for Older Adults: PSFS Mean Difference of 3.4 Posted· Jun 10, 2025
- Results postedSuicide Prevention: Engagement Strategies Trial Results Posted· Jun 8, 2025
- Results postedDepression: Enhanced BLT Support Shows Significant Differences in PHQ-9 Scores· Jun 6, 2025
- Results postedSeltorexant Phase 3 MDD with Insomnia Trial Misses Primary Endpoint· Jun 4, 2025· drug: Seltorexant
- Results postedDepression Psychotherapy Trial Shows No Significant Difference Between Arms· Jun 3, 2025
- Results postedSTEP-Home Workshop Improves Reintegration and Readjustment in Veterans· May 30, 2025
- Results postedAdolescent Depression: Online CFT Group Shows Higher Stress, Anxiety, Depression· May 30, 2025
- Results postedDepression: Closed-Loop tACS Shows Significant Symptom Reduction· May 29, 2025
- Results postedDepression: Therapist-Guided CBT App Shows Significant Symptom Reduction· May 28, 2025
- Results postedDepression: TMS Feasibility Study Posts EEG Correlates in Parkinson's Disease· May 21, 2025
- Results postedIxekizumab Phase 2 Trial for Major Depressive Disorder Reports Mean MADRS Change· May 20, 2025· drug: Ixekizumab
- Results postedDepression: Delta-beta tACS Augmentation Shows Similar Clinician-Rated Symptoms· May 20, 2025