Trial results for the Individualized Positive Psychosocial Intervention (IPPI) study, focusing on Depression, Dementia, and Behavior, were posted on ClinicalTrials.gov on 2025-11-03. The study enrolled 200 participants to assess the feasibility of the intervention.
Background
Depression and behavioral symptoms are common challenges among nursing home residents living with dementia. These symptoms can significantly impact quality of life for residents and present difficulties for care partners. Interventions that are feasible to deliver and can track impact through existing data sources, such as electronic medical records, are important for improving care in this vulnerable population. The Individualized Positive Psychosocial Intervention (IPPI) aims to address these needs by engaging residents in preference-based interactions.
Trial design
This completed study, designated as Phase NA, enrolled 200 participants. The trial investigated the feasibility of the Individualized Positive Psychosocial Intervention (IPPI) in nursing home residents living with Dementia and Depression or distress symptoms. The study aimed to determine if the IPPI could be delivered effectively and if its impact could be tracked using data from electronic medical records. Care partners were involved in delivering two brief preference-based IPPIs per week over six months.
Key results
The trial results posted include measurements of changes in various behavioral symptoms within the experimental group:
- For 'Change in Physical Behavioral Symptoms Directed Toward Others', participant counts were 4, 13, and 1.
- For 'Change in Verbal Behavior Symptoms Directed Towards Others', participant counts were 5, 12, and 3.
- For 'Change in Other Behavioral Symptoms Not Directed Towards Others', participant counts were 0, 18, and 0.
- For 'Change in Rejection of Care', participant counts were 5, 8, and 0.
What this means
The posted results provide data on the observed changes in behavioral symptoms among participants receiving the Individualized Positive Psychosocial Intervention. As a feasibility study, the primary goal was to assess the deliverability of the IPPI and the ability to track its impact through electronic medical records. The reporting of these behavioral change metrics indicates that data collection regarding these outcomes was conducted. While the specific direction or clinical significance of these changes cannot be inferred solely from the provided counts, the data suggests that the intervention's impact on various behavioral aspects was monitored within the study population of nursing home residents with dementia and depressive symptoms.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT05980299, titled 'Testing the Feasibility of the Individualized Positive Psychosocial Intervention (IPPI)', were posted on 2025-11-03 on clinicaltrials.gov.