Epilepsy — Trials, FDA Actions & Pivotal Research

20 active Epilepsy trials currently recruiting in the US, sourced from ClinicalTrials.gov.

Synced daily from openFDA and ClinicalTrials.gov. Last sync: June 12, 2026.

Recruiting trials by city

Cities where Epilepsy trials in our archive had recruiting sites. Each link lists every currently recruiting paid clinical trial at that location.

Boston, MA Palo Alto, CA San Francisco, CA Cleveland, OH Stanford, CA Birmingham, AL Chicago, IL Jacksonville, FL Miami, FL Worcester, MA Boise, ID Cincinnati, OH

Active Epilepsy trials

Currently recruiting US trials matching Epilepsy, sourced live from ClinicalTrials.gov. We’ll add per-event articles here as those trials post results or hit primary completion.

Cholinergic Enhancement of Theta

for Epilepsy

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07228338·EARLY_Phase 1·Not Yet Recruiting

Sleep-Driven Adaptive Neuromodulation in Lennox-Gastaut Syndrome

for Lennox Gastaut Syndrome (LGS)

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65

Code: NCT07568860·Not Yet Recruiting

Study of the Pharmacokinetics, Safety, and Tolerability of ZONISADE in Children 1 Month to 17 Years of Age With Partial-onset Seizures

for Seizures

2 locations incl. Winston-Salem

Sponsor: Azurity Pharmaceuticals

Sex: All·Age: 1 Month - 17

Code: NCT06534502·Phase 4·Not Yet Recruiting

Evaluation of the FYNA Research OPM MEG Device for Locating Epileptic Foci as Part of Pre-surgical Assessment of Epilepsy

for Epilepsy

Sponsor: Hospices Civils de Lyon

Sex: All·Age: 6 - 65

Code: NCT07281222·Not Yet Recruiting

Assessment of MRI-guided HIFU for Patients With Drug-resistant Focal Epilepsy

for Epilepsy

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18+

Code: NCT07591350·Not Yet Recruiting

Biomarker Targeted Stimulation for Epileptiform Events

for Epilepsy

Sponsor: Cadence Neuroscience

Sex: Male·Age: 7+

Code: NCT06424977·Not Yet Recruiting

Intracranial CArtography of Cortical Contribution to Respiratory Load Compensation in Epilepsy

for Epilepsy

Sponsor: Hospices Civils de Lyon

Sex: All·Age: 18 - 55

Code: NCT07599150·Not Yet Recruiting

Health Literacy Project

for Epilepsy

Sponsor: Duke University

Sex: All·Age: 12 - 18

Code: NCT06634901·Not Yet Recruiting

Acute Stimulation and Modulation of Stereotyped High-Frequency Oscillations

for Epilepsy

2 locations incl. Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 3 - 70

Code: NCT06898138·Not Yet Recruiting

The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy

for Epilepsy

Sponsor: Xuanwu Hospital, Beijing

Sex: All·Age: 18 - 60

Code: NCT07095933·EARLY_Phase 1·Recruiting

Apply to this trial

Cenobamate in the Intensive Care Unit

for Epilepsy

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06352723·EARLY_Phase 1·Not Yet Recruiting

Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

for Epilepsy

12 locations incl. Phoenix

Sponsor: Epiminder America, Inc.

Sex: All·Age: 18 - 75

Code: NCT07110454·Recruiting

Apply to this trial

Epileptiform Potential of Fully Immersive Virtual Reality

for Epilepsy

1 location in Lebanon

Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All·Age: 13+

Code: NCT07451093·Not Yet Recruiting

Lily's Grace Temporal Interference

for Epilepsy

1 location in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18 - 75

Code: NCT07520955·Not Yet Recruiting

PREDiction of Different Variants of Sleep Stages for the Diagnosis Support of Chronic Insomnia and Epilepsy

for Chronic Insomnia

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18 - 65

Code: NCT07547501·Not Yet Recruiting

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures

for Focal Seizure

2 locations incl. Bentonville

Sponsor: Rapport Therapeutics Inc.

Sex: All·Age: 18 - 75

Code: NCT07594119·Phase 3·Recruiting

Apply to this trial

Neural Basis of Cognition

for Epilepsy

Sponsor: Duke University

Sex: All·Age: 12+

Code: NCT05132543·Not Yet Recruiting

AI-Based Mobile Intervention on Medication Non-Adherence and Transition

for Epilepsy

2 locations incl. Orlando

Sponsor: University of Central Florida

Sex: All·Age: 14 - 24

Code: NCT07445074·Recruiting

Apply to this trial

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1

for Focal Seizure

2 locations incl. Palmdale

Sponsor: Rapport Therapeutics Inc.

Sex: All·Age: 18 - 75

Code: NCT07563881·Phase 3·Recruiting

Apply to this trial

A Phase I Clinical Trial of UX-GIP001 in the Treatment of Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy

for Epilepsy

Sponsor: Shanghai UniXell Biotechnology Co., Ltd

Sex: All·Age: 18 - 75

Code: NCT07572812·Phase 1·Not Yet Recruiting