Huntington's Disease — Trials, FDA Actions & Pivotal Research

20 active Huntington's Disease trials currently recruiting in the US, sourced from ClinicalTrials.gov.

Synced daily from openFDA and ClinicalTrials.gov. Last sync: June 12, 2026.

Recruiting trials by city

Cities where Huntington's Disease trials in our archive had recruiting sites. Each link lists every currently recruiting paid clinical trial at that location.

Birmingham, AL Boston, MA Englewood, CO Orlando, FL Columbus, OH Irvine, CA Palo Alto, CA Seattle, WA

Active Huntington's Disease trials

Currently recruiting US trials matching Huntington's Disease, sourced live from ClinicalTrials.gov. We’ll add per-event articles here as those trials post results or hit primary completion.

Pridopidine Phase 3 Study in Huntington's Disease

for Huntington Disease

Sponsor: Prilenia

Sex: All·Age: 23 - 65

Code: NCT07609108·Phase 3·Not Yet Recruiting

A First-in-human Study of the Effects of SRP-1005 in Participants With Huntington's Disease

for Huntington's Disease

Sponsor: Sarepta Therapeutics, Inc.

Sex: All·Age: 21 - 70

Code: NCT07536061·Phase 1·Recruiting

Apply to this trial

Mass Balance Study of [14C] LPM3770164 in Healthy Participants

for Huntington Disease

Sponsor: Luye Pharma Group Ltd.

Sex: Male·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07516899·Phase 1·Not Yet Recruiting

Optimizing Parameters of Low-Intensity Focused Ultrasound for Pallidal Modulation in Huntington's Disease

for Huntington Disease

Sponsor: First Affiliated Hospital of Fujian Medical University

Sex: All·Age: 18 - 75

Code: NCT07513844·Recruiting

Apply to this trial

Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease

for Huntington Disease

1 location in Irvine

Sponsor: Leslie Thompson

Sex: All·Age: 18 - 65

Code: NCT07451613·Phase 1, Phase 2·Recruiting

Apply to this trial

Autobiographical Memory, Future Thought, and Eye Movements in Huntington's Disease

for Huntington Disease

Sponsor: University Hospital, Angers

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07409597·Not Yet Recruiting

A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

for Huntington Disease

9 locations incl. Englewood

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 21 - 70

Code: NCT07326709·Phase 3·Recruiting

Apply to this trial

iMagemHTT-009- FIH Evaluation of Novel Mutant Huntingtin PET Radioligand [11C]CHDI-00491009

for Huntington Disease

Sponsor: CHDI Foundation, Inc.

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT06634628·EARLY_Phase 1·Recruiting

Apply to this trial

Multi-Modal Digital Monitoring of Disease Symptoms Huntington's Disease

for Huntington Disease

2 locations incl. Rochester

Sponsor: BioSensics

Sex: All·Age: 25 - 65·Accepts healthy volunteers

Code: NCT07315984·Not Yet Recruiting

Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease

for Huntington Disease

Sponsor: Skyhawk Therapeutics, Inc.

Sex: All·Age: 25+

Code: NCT07378644·Phase 2, Phase 3·Recruiting

Apply to this trial

Evaluation of Three Tests to Assess Social Cognition in Huntington Disease

for Huntington Disease

Sponsor: Region Skane

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07253038·Recruiting

Apply to this trial

Modification of Threat Interpretation Bias to Reduce Anxiety in Neurodegenerative Movement Disorders (Aim 3)

for Huntington Disease

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 21+

Code: NCT07213648·Recruiting

Apply to this trial

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RG6496 in Huntington's Disease

for Huntington's Disease

Sponsor: Hoffmann-La Roche

Sex: All·Age: 25 - 65

Code: NCT07246941·Phase 1·Recruiting

Apply to this trial

Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease

for Huntington Disease

1 location in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18 - 85

Code: NCT06843252·Recruiting

Apply to this trial

Hinting Task for Huntington's Disease

for Huntington Disease

Sponsor: University Medical Center Groningen

Sex: All·Age: 18 - 74

Code: NCT06774443·Recruiting

Apply to this trial

Transcranial Static Magnetic Stimulation (tSMS) in Huntington's Disease (HD)

for Huntington Disease

Sponsor: Neuromed IRCCS

Sex: All·Age: All ages

Code: NCT06976983·Not Yet Recruiting

Gut Microbiomes in HD

for Huntington Disease

1 location in Orlando

Sponsor: University of Central Florida

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06448546·Recruiting

Apply to this trial

Cognitive Assessment Tools for Huntington's Disease.

for Huntington Disease

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 30 - 65

Code: NCT06546488·Recruiting

Apply to this trial

Digital Measures for Clinical Trial Endpoints in Huntington's Disease

for Huntington Disease

1 location in Rochester

Sponsor: University of Rochester

Sex: All·Age: 25 - 65·Accepts healthy volunteers

Code: NCT07010705·Recruiting

Apply to this trial

The NAD-HD Study: A Study to Investigate Efficacy and Safety of Nicotinamide Riboside Compared With Placebo in Huntington's Disease

for Huntington Disease

Sponsor: Oslo University Hospital

Sex: All·Age: 18 - 80

Code: NCT06853743·Phase 2·Recruiting

Apply to this trial