Sjogren Syndrome — Trials, FDA Actions & Pivotal Research

15 active Sjogren Syndrome trials currently recruiting in the US, sourced from ClinicalTrials.gov.

Synced daily from openFDA and ClinicalTrials.gov. Last sync: June 12, 2026.

Recruiting trials by city

Cities where Sjogren Syndrome trials in our archive had recruiting sites. Each link lists every currently recruiting paid clinical trial at that location.

Birmingham, AL Los Angeles, CA Orlando, FL

Active Sjogren Syndrome trials

Currently recruiting US trials matching Sjogren Syndrome, sourced live from ClinicalTrials.gov. We’ll add per-event articles here as those trials post results or hit primary completion.

R-2487 in Patients With Sjogren's Syndrome (SS)

for Sjogren's Syndrome

Sponsor: Rise Therapeutics LLC

Sex: All·Age: 18 - 80

Code: NCT06297213·Phase 1·Not Yet Recruiting

Fatigue in Sjögren's Syndrome: 3 Therapeutic Strategies

for Sjogren Syndrome

Sponsor: Centre Hospitalier Universitaire de Saint Etienne

Sex: All·Age: 18+

Code: NCT06875102·Recruiting

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TREATMENT OF VAGINAL DRYNESS IN SJÖGREN'S DISEASE WITH CO2-LASER VERSUS TOPICAL PROMESTRIENE

for Sjogren Syndrome

Sponsor: University of Sao Paulo General Hospital

Sex: Female·Age: 30 - 65

Code: NCT07153276·Phase 4·Recruiting

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Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune Diseases

for System Lupus Erythematosus

Sponsor: Peking University Third Hospital

Sex: All·Age: 18 - 80

Code: NCT07301164·EARLY_Phase 1·Not Yet Recruiting

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Sjogren's Disease

for Sjögren

5 locations incl. Orlando

Sponsor: Cullinan Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT07041099·Phase 1·Recruiting

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AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

for Refractory Rheumatoid Arthritis (RA)

31 locations incl. Tuscaloosa

Sponsor: Artiva Biotherapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06991114·Phase 2·Recruiting

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Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases

for Systemic Lupus Erthematosus

Sponsor: Peking University Third Hospital

Sex: All·Age: 18 - 80

Code: NCT06828042·Phase 1, Phase 2·Recruiting

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Safety and Efficacy of Universal CAR-T Cells (UWD-CD19) Combined with Immunosuppressants in the Treatment of Refractory Autoimmune Diseases

for Systemic Lupus Erthematosus

Sponsor: Peking University Third Hospital

Sex: All·Age: 18 - 80

Code: NCT06821659·Phase 1, Phase 2·Not Yet Recruiting

"Core Stabilization Strenght and Pelvic Floor Functions in Primary Sjogren's"

for Sjogren Syndrome

Sponsor: Pamukkale University

Sex: Female·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06879444·Enrolling By Invitation

BCMA-CD19 CAR-T Therapy for Refractory Autoimmune Diseases

for Systemic Lupus Erythematosus

Sponsor: Peking University People's Hospital

Sex: All·Age: 18 - 65

Code: NCT06794008·Phase 2·Recruiting

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Ultrasonic COmparison of Salivary Glands in Autoimmune Diseases (COUGAR)

for Sjogren Syndrome

Sponsor: University Hospital, Brest

Sex: All·Age: All ages

Code: NCT06680310·Not Yet Recruiting

Rare AutoImmune SElf-management Programme Development

for Systemic Lupus Erthematosus

Sponsor: University of the West of England

Sex: All·Age: 18+

Code: NCT06642870·Recruiting

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Interferon Signature in Anti-CTLA-4 and Anti-PD-1/PD-L1-Treated Cancer Patients Compared With Systemic Autoimmune Disease Patients

for Immune-Related Adverse Events

Sponsor: Hospital Universitario Araba

Sex: All·Age: 18+

Code: NCT07249060·Recruiting

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

51 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting

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The Myelin Disorders Biorepository Project

for Leukodystrophy

23 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT03047369·Recruiting

Apply to this trial