Trial results for a study evaluating a Technology Enabled Service (TES) in perinatal depression were posted on ClinicalTrials.gov on 2025-09-12, involving 75 participants.
Background
Depression, particularly in the perinatal period, represents a significant public health challenge, affecting individuals during pregnancy and after childbirth. This period is associated with unique stressors and vulnerabilities, making effective and accessible mental health support crucial. Collaborative care services, which integrate mental health care into primary care settings like obstetrics clinics, have shown promise. The integration of Technology Enabled Services (TES) within these models aims to further enhance support, improve patient engagement, and potentially overcome barriers to care, thereby improving outcomes for individuals experiencing perinatal depression.
Trial design
This completed study, designated as Phase NA, enrolled 75 participants to investigate Depression. The trial evaluated a Technology Enabled Service (TES) designed to support the treatment of depression within a collaborative care framework in obstetrics clinics. The intervention aimed to provide enhanced support compared to eTreatment as Usual.
Key results
The trial reported several key measurements across different outcomes:
- Depression (score on a scale):
- For the Technology Enabled Service group, the Least Squares Mean was 6.42.
- For the eTreatment as Usual group, the Least Squares Mean was 6.55.
- Anxiety (score on a scale):
- For the Technology Enabled Service group, the Least Squares Mean was 6.57.
- For the eTreatment as Usual group, the Least Squares Mean was 7.38.
- Satisfaction Index - Mental Health (score on a scale):
- For the Technology Enabled Service group, the Median was 58.
- For the eTreatment as Usual group, the Median was 62.
- For the Technology Enabled Service group, the Median was 62.
- For the eTreatment as Usual group, the Median was 60.
- TWente Engagement With Ehealth Technologies Scale (TWEETS) (score on a scale):
- For the Technology Enabled Service group, the Median was 38.
- For the eTreatment as Usual group, the Median was 26.
- For the Technology Enabled Service group, the Median was 35.
- For the eTreatment as Usual group, the Median was 27.
What this means
The posted results suggest that the Technology Enabled Service (TES) may offer some benefits for individuals with perinatal depression. Participants in the TES group showed slightly lower least squares mean scores for both depression (6.42 vs. 6.55) and anxiety (6.57 vs. 7.38) compared to those receiving eTreatment as Usual. Notably, engagement with e-health technologies, as measured by the TWEETS scale, was higher in the TES group (Medians of 38 and 35 vs. 26 and 27). While satisfaction index results were mixed, the observed trends in mental health scores and engagement indicate that integrating technology-enabled support could be a valuable component of collaborative care for perinatal depression, potentially improving patient outcomes and interaction with digital health tools.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT05525689, titled "Evaluating Technology Enabled Services in Perinatal Depression", were posted on 2025-09-12 on clinicaltrials.gov.