Trial results for an eHealth intervention aimed at increasing Depression treatment initiation and adherence among Veterans were posted on ClinicalTrials.gov on 2025-11-21, with 47 participants enrolled in the self-monitoring group.
Background
Depression is identified as the most prevalent mental health condition among Veterans Health Administration (VHA) patients, significantly linked to poor functioning, negative health outcomes, and an increased risk of suicide. Despite the availability of effective treatments, patient engagement in care remains a challenge. This study addresses this gap by aiming to improve and sustain engagement in mental health care through the development and evaluation of an eHealth intervention focused on self-monitoring.
Trial design
This study, identified as Phase NA, enrolled a total of 47 participants, all diagnosed with Depression. The trial's objective was to develop and formatively evaluate an eHealth intervention designed to enhance and maintain engagement in mental health care through self-monitoring among Veterans referred for mental health services. The intervention involved self-monitoring, and the study analyzed VHA electronic medical record data to identify patient characteristics associated with poor treatment engagement. There were no comparator arms specified in the provided data.
Key results
The trial results detail several key measurements related to participant engagement and treatment efficacy within the self-monitoring group:
- The incidence of intervention enrollment, as assessed by completion of the baseline survey, included 47 participants.
- The number of patients with completed tasks, as measured by Mental Health Link, was reported as 47 participants in one instance and 25 participants in another.
- The efficacy of the intervention, assessed by the rate of Depression treatment initiation and adherence, was reported with participant counts of 32, 28, and 18 for different aspects or time points of this outcome.
What this means
The posted results provide initial insights into the feasibility and reach of an eHealth self-monitoring intervention for Veterans with Depression. With 47 participants completing the baseline survey and engaging in tasks, the study demonstrates the ability to enroll and initiate engagement with such an intervention. The varying counts for task completion and treatment initiation/adherence (e.g., 47 vs. 25 for tasks, and 32, 28, 18 for efficacy measures) suggest different levels or stages of engagement and adherence within the participant group. These findings indicate that eHealth interventions can play a role in addressing the challenge of poor treatment engagement among Veterans with Depression, warranting further investigation into the factors influencing sustained adherence.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT05990075, titled "An eHealth Intervention to Increase Depression Treatment Initiation and Adherence Among Veterans Referred for Mental Health Services", were posted on 2025-11-21 on clinicaltrials.gov.