Trial results for The BE WITH Project, a study investigating mental health in older adults with Depression, were posted on 2025-11-12. The study enrolled 671 participants.

Background

Depression, loneliness, and social isolation are significant concerns for older adults, impacting their overall mental health and well-being. Interventions aimed at improving social connections and support can play a crucial role in mitigating these challenges. The BE WITH (Belonging through Empathy With Intentional Targeted Helping) innovation was developed to address these issues by providing an 8-week standardized and manualized warm calling treatment. The trial sought to determine if this innovation could improve mental health outcomes for older adults and to identify the specific treatment components contributing to any observed improvements.

Trial design

This completed study, identified as Phase NA, enrolled 671 participants. The trial focused on older adults experiencing conditions such as Mental Health concerns, Depression, Loneliness, and Social Isolation. The intervention involved an 8-week standardized and manualized warm calling treatment. The study compared two active treatment conditions, the BE (Belonging through Empathy) condition and the BE + ASIST (Applied Suicide Intervention Skills Training) condition, against a control group. The primary outcomes, as stated in the trial's brief summary, aimed to assess whether mental health outcomes improved for the treatment conditions relative to the control group, though specific primary outcome measures were not detailed in the provided data.

Key results

The trial measured the Social Provisions Scale (SPS-5) across the different groups. The scores are presented as mean (standard deviation) on a scale:

What this means

The posted results provide mean scores for the Social Provisions Scale (SPS-5) across the BE, BE + ASIST, and control groups. The trial aimed to assess if the BE WITH innovation improved mental health outcomes for older adults. Based solely on the presented mean scores, which show similar values across all groups, direct conclusions regarding the efficacy of the interventions in improving mental health outcomes, as measured by SPS-5, cannot be drawn without further statistical analysis or context on the scale's interpretation and baseline data. These data contribute to the overall understanding of the trial's findings.

Source

The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT07204444, titled "The BE WITH Project: A Partially Nested Randomized Control Trial (PN-RCT)", were posted on 2025-11-12 on clinicaltrials.gov.