Paid Clinical Trials in Ohio
Ohio has 3,475 paid clinical trials enrolling now across cities including Columbus, Cleveland and Cincinnati. Search by condition, age, or phase to find compensated research studies accepting participants near you.
Research sites in Ohio include Cleveland Clinic, Ohio State Wexner Medical Center and Cincinnati Children's, running studies across oncology, cardiology, neurology, and more. The most actively recruiting conditions are Breast Cancer, Heart Failure, Endometrial Cancer, Ovarian Cancer — browse the full list or use the filters to match your diagnosis. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Filter results
3,475 clinical trials
↓ Download CSVNT-3 Levels and Function in Individuals With CMT
REstoring Flow by REvascularization With Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic Stenosis
Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
GLP-1 RA for Stage 1 Type 1 Diabetes
Pilot Studies Testing the Use of Oral Amitriptyline in Reducing Localized Burn Injury-induced Microvesicle Particle Release
Phase I/IIa Trial of scAAV1.tMCK.NTF3 for Treatment of CMT1A
REFRAME: an Emotion Regulation Intervention to Improve Psychological Outcomes in Surrogate Decision-Makers of the Critically Ill
SPI-1005 in Adults Receiving Cochlear Implant
Shape-sensing Versus Electromagnetic Robotic Bronchoscopy for Evaluation of PulmoNary LEsions
Dietary Fiber and Time Restricted Eating
Under-Represented Communities Diagnosed With SCD or MCI Through Tele-Cog
Symptoms of Polycystic Ovarian Syndrome Ameliorated by Keto-Adaptation Pilot
Safety And Effectiveness Of NaviFUS System With Bevacizumab In Recurrent Glioblastoma
Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma
Metabolic Surgery for Atrial Fibrillation Elimination
A Study to Evaluate the Efficacy and Safety of CBL-514 Injection for Reducing Subcutaneous Fat ( SUPREME-02 )
Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus
Study of Serine Supplementation to Protect Vision in MacTel
VitaSmart HOPE System: Bridge to HOPE Registry
Phase II Trial of Zanzalitinib in Patients With Metastatic Castration Resistant Prostate Cancer
Lumbar Punctures for the Detection of ctDNA in the Cerebrospinal Fluid of Patients With Stage III and IV Non-Small Cell Lung Cancer
A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism
A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum Disorder
Treating Passive Structure Knowledge Deficits in School-Age Children With Developmental Language Disorder
Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations
Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei (TRANSCAPE)
AI-guided Prediction and Treatment of Cardiac Arrest
The BRIDGE Pain Study
A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 Diabetes
User Evaluation of Advanced Personalized Modular Pressure Relief Seating Cushion Systems
A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients
Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy
Surgical Ergonomics in OBGYN
Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation
Mindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET)
Life Expectancy-informed Colorectal Cancer Screening
Hybrid Delivery to Increase Access and Sustainability: Evaluating ezParent Implementation
OMT for Adhesive Capsulitis
Studying the Impacts of Higher Taxes and Bans on Electronic Cigarettes to Improve Public Health
About research studies in Ohio
Ohio has approximately 3,475 recruiting research studies across a wide range of therapeutic areas. Ohio is home to The Ohio State University Wexner Medical Center, Cleveland Clinic, Cincinnati Children's, and University Hospitals Cleveland Medical Center — collectively running clinical trials across every major therapeutic area.
Common conditions studied in Ohio
- Breast Cancer (50 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Heart Failure (41 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Endometrial Cancer (38 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Ovarian Cancer (38 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Prostate Cancer (38 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Advanced Solid Tumor (34 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Ohio
- Children's Hospital Medical Center, Cincinnati
- Ohio State University
- The Cleveland Clinic
- National Cancer Institute (NCI)
- Ohio State University Comprehensive Cancer Center
Local regulations and guidelines
Clinical trials in Ohio are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Ohio research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Ohio. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Ohio
Hipa.ai aggregates every recruiting study in Ohio from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Ohio?
There are approximately 3,475 recruiting clinical trials in Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Ohio pay participants?
Most recruiting trials in Ohio compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Ohio?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Ohio?
The most common conditions under active study in Ohio include Breast Cancer (50), Heart Failure (41), Endometrial Cancer (38), Ovarian Cancer (38), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Ohio?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Ohio on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Ohio?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.