Study of SGR-3515 In Participants With Advanced Solid Tumors.
Part of paid clinical trials in New Haven, Connecticut.
- Sponsor
- Schrödinger, Inc.
- Study ID
- NCT06463340
- Phase
- PHASE1
- Status
- Recruiting
Conditions
- Advanced Solid Tumor
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- SGR-3515 — DRUGSGR-3515 will be administered orally with an intermittent schedule.
Study Details
The purpose of this study is to learn about the effects of a new study drug, called SGR-3515 that may be a treatment for advanced solid tumors.
Key Dates
- Start date
- Jun 18, 2024
- Status verified
- Jul 2025
- Primary completion
- Oct 31, 2026
- Completion
- Dec 31, 2026
Study Design
- Enrollment
- 52 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: Dose Escalation28-day treatment cycle.
Primary Outcome Measure
Incidence and severity of adverse events (AEs) [ Time Frame: Day 1 to 28 days after the last dose of SGR-3515. ]
Central Contacts
- Study Physician+15032991150
Locations (13)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Yale University, Yale Cancer Center | New Haven | Connecticut | 06520 | Patricia LoRusso, DO (PRINCIPAL_INVESTIGATOR) |
| Northwestern University | Chicago | Illinois | 60611 | Pedro de Viveiros, MD (PRINCIPAL_INVESTIGATOR) |
| University of Michigan | Ann Arbor | Michigan | 48109 | Jean Siedel, DO (PRINCIPAL_INVESTIGATOR) |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | Ira Winer, MD (PRINCIPAL_INVESTIGATOR) |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | Deborah Doroshow, MD (PRINCIPAL_INVESTIGATOR) |
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | Robert W Naumann, MD (PRINCIPAL_INVESTIGATOR) |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45267 | Amanda Jackson, MD (PRINCIPAL_INVESTIGATOR) |
| Ohio State University | Columbus | Ohio | 43210 | John Hays, MD (PRINCIPAL_INVESTIGATOR) |
| Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | Kathleen N Moore, MD (PRINCIPAL_INVESTIGATOR) |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | Vivek Subbiah, MD (PRINCIPAL_INVESTIGATOR) |
| Vanderbilt-Ingram Cancer Center/Henry-Joyce Cancer Clinic | Nashville | Tennessee | 37232 | Michael K Gibson, MD (PRINCIPAL_INVESTIGATOR) |
| University of Texas Southwestern | Dallas | Texas | 75235 | David Miller, MD (PRINCIPAL_INVESTIGATOR) |
| NEXT Virginia | Fairfax | Virginia | 22031 | Mohamad A Salkeni, MD (PRINCIPAL_INVESTIGATOR) |
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