Study of SGR-3515 In Participants With Advanced Solid Tumors.

Part of paid clinical trials in New Haven, Connecticut.

Sponsor
Schrödinger, Inc.
Study ID
NCT06463340
Phase
PHASE1
Status
Recruiting

Conditions

  • Advanced Solid Tumor

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • SGR-3515 — DRUG
    SGR-3515 will be administered orally with an intermittent schedule.

Study Details

The purpose of this study is to learn about the effects of a new study drug, called SGR-3515 that may be a treatment for advanced solid tumors.

Key Dates

Start date
Jun 18, 2024
Status verified
Jul 2025
Primary completion
Oct 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
52 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Dose Escalation
    28-day treatment cycle.

Primary Outcome Measure

Incidence and severity of adverse events (AEs) [ Time Frame: Day 1 to 28 days after the last dose of SGR-3515. ]

Central Contacts

Locations (13)

FacilityCityStateZIPSite coordinators
Yale University, Yale Cancer CenterNew HavenConnecticut06520
Patricia LoRusso, DO (PRINCIPAL_INVESTIGATOR)
Northwestern UniversityChicagoIllinois60611
Pedro de Viveiros, MD (PRINCIPAL_INVESTIGATOR)
University of MichiganAnn ArborMichigan48109
Jean Siedel, DO (PRINCIPAL_INVESTIGATOR)
Karmanos Cancer InstituteDetroitMichigan48201
Ira Winer, MD (PRINCIPAL_INVESTIGATOR)
Icahn School of Medicine at Mount SinaiNew YorkNew York10029
Deborah Doroshow, MD (PRINCIPAL_INVESTIGATOR)
Levine Cancer InstituteCharlotteNorth Carolina28204
Robert W Naumann, MD (PRINCIPAL_INVESTIGATOR)
University of Cincinnati Medical CenterCincinnatiOhio45267
Amanda Jackson, MD (PRINCIPAL_INVESTIGATOR)
Ohio State UniversityColumbusOhio43210
John Hays, MD (PRINCIPAL_INVESTIGATOR)
Stephenson Cancer CenterOklahoma CityOklahoma73104
Kathleen N Moore, MD (PRINCIPAL_INVESTIGATOR)
Sarah Cannon Research InstituteNashvilleTennessee37203
Vivek Subbiah, MD (PRINCIPAL_INVESTIGATOR)
Vanderbilt-Ingram Cancer Center/Henry-Joyce Cancer ClinicNashvilleTennessee37232
Michael K Gibson, MD (PRINCIPAL_INVESTIGATOR)
University of Texas SouthwesternDallasTexas75235
David Miller, MD (PRINCIPAL_INVESTIGATOR)
NEXT VirginiaFairfaxVirginia22031
Mohamad A Salkeni, MD (PRINCIPAL_INVESTIGATOR)

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