As of June 2026, 1,330 paid clinical trials are recruiting in Pittsburgh, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Pittsburgh offers studies at sites including University of Pittsburgh for conditions such as Breast Cancer, Melanoma, Stroke, Endometrial Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Pittsburgh has approximately 1,330 recruiting research studies across a wide range of therapeutic areas. Pennsylvania hosts UPenn's Perelman School of Medicine and Children's Hospital of Philadelphia — pioneers in CAR-T cell therapy — alongside UPMC, Thomas Jefferson University, and Penn State Hershey.
Researchers run research studies in Pittsburgh, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Pittsburgh | Stroke, Traumatic Brain Injury, Dementia | 164 |
| University of Pittsburgh Medical Center | Chronic Pancreatitis, Cystic Fibrosis, Advanced Solid Tumor | 147 |
| UPMC Hillman Cancer Center | Melanoma, Glioma, Hepatocellular Carcinoma | 87 |
| University of Pittsburgh Cancer Institute (UPCI) | Acute Myeloid Leukemia, Metastatic Malignant Solid Neoplasm, Anatomic Stage IV Breast Cancer AJCC v8 | 87 |
| Allegheny General Hospital | Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Cancer | 67 |
| Children's Hospital of Pittsburgh of UPMC | B Acute Lymphoblastic Leukemia, Mixed Phenotype Acute Leukemia, Neuroblastoma | 61 |
| UPMC Children's Hospital of Pittsburgh | Biliary Atresia, Fabry Disease, Congenital Bone Marrow Failure Syndromes | 55 |
| UPMC-Passavant Hospital | Recurrent Endometrial Carcinoma, Anatomic Stage II Breast Cancer AJCC v8, Prostate Adenocarcinoma | 39 |
| Allegheny Health Network | Atrial Fibrillation, Bladder Cancer, Brain Tumor | 35 |
| UPMC-Saint Clair Hospital Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Head and Neck Squamous Cell Carcinoma | 30 |
| UPMC-Saint Margaret | Prostate Adenocarcinoma, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 27 |
| West Penn Hospital | Breast Cancer, Large B-cell Lymphoma, Stage IV Colorectal Cancer AJCC v8 | 27 |
| UPMC-Magee Womens Hospital | Breast Cancer, Recurrent Endometrial Carcinoma, Anatomic Stage II Breast Cancer AJCC v8 | 26 |
| UPMC-Shadyside Hospital | Stage IV Renal Cell Cancer AJCC v8, Breast Cancer, Head and Neck Squamous Cell Carcinoma | 26 |
| UPMC | Focal Epilepsy, Ovarian Cancer, ASD - Atrial Septal Defect | 23 |
| UPMC Presbyterian | Acute Kidney Injuries, Aneurysm of Aorta, Thoracic, Aneurysmal Disease | 20 |
| VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA | Cardiovascular Diseases, Stroke, Acute Kidney Injury | 20 |
| Children's Hospital of Pittsburgh | Diabetes Mellitus, Type 2, Hyperglycemia, Physical Inactivity | 19 |
| UPMC Presbyterian Hospital | Abdominal Surgery, Acute Ischemic Stroke, Acute Myocardial Infarction | 18 |
| UPMC Magee-Womens Hospital | ADHD, Behavioral Intervention, Breast Cancer | 9 |
| UPMC Shadyside Hospital | Opioid Use Disorder, Abdominal Surgery, Anxiety Preoperative | 9 |
| University of Pittsburgh School of Medicine | Adolescents, Anorexia Nervosa, Bipolar Disorder (BD) | 9 |
| AHN West Penn Hospital | Malignant Mesothelioma, Malignant Pleural Effusion, Metastasis to Pleura | 8 |
| University of Pittsburgh Medical Center (UPMC) | ALS, ALS (Amyotrophic Lateral Sclerosis), ALS - Amyotrophic Lateral Sclerosis | 8 |
| UPMC-Presbyterian Hospital | Metastatic Malignant Neoplasm in the Brain, Stage IV Lung Cancer AJCC v8, Adenocarcinoma of the Colon | 7 |
Recruiting trials in Pittsburgh grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in Pennsylvania are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Pennsylvania research additionally follows state public health department oversight and any applicable state privacy statutes.
Hipa.ai aggregates every recruiting study in Pittsburgh from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 1,330 recruiting clinical trials in Pittsburgh, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Pittsburgh compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Pittsburgh include Breast Cancer (26), Cancer (20), Melanoma (19), Stroke (18), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Pittsburgh on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Pittsburgh include University of Pittsburgh, University of Pittsburgh Medical Center, UPMC Hillman Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Pittsburgh are Cancer & tumors (440), Neurology & pain (87), Cardiovascular (74). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.