Paid Clinical Trials in Allentown, PA
As of June 2026, 139 paid clinical trials are recruiting in Allentown, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Allentown offers studies at sites including Lehigh Valley Hospital-Cedar Crest for conditions such as Acute Myeloid Leukemia, Major Depressive Disorder, Anatomic Stage IV Breast Cancer AJCC v8, B Acute Lymphoblastic Leukemia. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Allentown
Trials by drug in Allentown
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139 clinical trials
↓ Download CSVPost Approval Effectiveness and Durability Evaluation of the Altaviva™ Tibial Device
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
Lead Evaluation for Defibrillation and Reliability Post Approval Study
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE)
Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients
Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment
A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant Tumors
An Open-Label Study of Azetukalner in Major Depressive Disorder
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Prevail Global Study
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE
Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body
Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)
Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)
About research studies in Allentown
Allentown has approximately 139 recruiting research studies across a wide range of therapeutic areas. Pennsylvania hosts UPenn's Perelman School of Medicine and Children's Hospital of Philadelphia — pioneers in CAR-T cell therapy — alongside UPMC, Thomas Jefferson University, and Penn State Hershey.
Top Research Study Locations in Allentown
Researchers run research studies in Allentown, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Lehigh Valley Hospital-Cedar Crest | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy | 70 |
| Lehigh Valley Health Network | AAA, AAA - Abdominal Aortic Aneurysm, Acute Leukemia | 16 |
| Saint Luke's Cancer Center - Allentown | Metastatic Malignant Neoplasm in the Brain, Pancreatic Neoplasm, Stage IV Lung Cancer AJCC v8 | 13 |
| Lehigh Center for Clinical Research | Bipolar Depression, Bipolar Disorder, Bipolar I Disorder | 9 |
| Lehigh Valley Hospital | Aneurysm, Aortic Arch, Aortic Diseases | 6 |
| Lehigh Valley Health Network (Data Collection Only) | Breast Cancer, Clinical Stage: Stage II (T3-4, N-), ER+ Breast Cancer | 5 |
| Lehigh Valley Hospital - Cedar Crest | Advanced Solid Tumors, Atrial Fibrillation, Coronary Artery Disease | 4 |
| Lehigh Valley Topper Cancer Institute | AML, AML With Mutated NPM1, Acute Leukemia | 2 |
| 008 | Diabetic Foot Ulcer | 1 |
| Carepath Injury Ctr of Pennsylvania | Lumbar Spinal Stenosis | 1 |
| Cedar Crest Surg Ctr | Lumbar Spinal Stenosis | 1 |
| Institute for Female Pelvic Medicine and Reconstructive Surgery | Urge Urinary Incontinence | 1 |
| Jefferson Health - Lehigh Valley Health Network | Upper Extremity Problem | 1 |
| Lehigh Valley Health Network- Cedar Crest | Langerhans Cell Histiocytosis | 1 |
| Lehigh Valley Hospital Inc. | AV Block, Heart Failure, Heart Failure With Reduced Ejection Fraction | 1 |
| Lehigh Valley Topper Cancer Center Institute | Large B-cell Lymphoma, Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma | 1 |
| Local Institution - 0020 | Advanced Malignant Tumors | 1 |
| Local Institution - 0037 | Cancer | 1 |
| Local Institution - 0359 | Relapsed or Refractory Multiple Myeloma | 1 |
| Local Institution - 0433 | Metastatic Castration-resistant Prostate Cancer | 1 |
| Local Institution - 1019 | Psychosis Associated With Alzheimer's Disease | 1 |
| Local Institution - Unk041 | Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer | 1 |
| Seaport Investigator Site | Major Depressive Disorder (MDD), Major Depressive Disorder With Anxious Distress | 1 |
| St Luke's University Health, Sacred Heart Campus | Brain Tumor, Brain Tumor - Metastatic, Brain Tumor, Adult Meningioma | 1 |
| St. Luke's University Health Network | AV Block, Heart Failure, Heart Failure With Reduced Ejection Fraction | 1 |
Active & Upcoming Studies in Allentown (2026)
Recruiting trials in Allentown grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (84 active studies)
- Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays · Alliance for Clinical Trials in Oncology
- A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer · Phase 2, Phase 3 · Bristol-Myers Squibb
Cardiovascular (7 active studies)
- LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2 · Phase 3 · Tenax Therapeutics, Inc.
- Prevail Global Study · Medtronic Vascular
Mental health & behavior (5 active studies)
- An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE) · Phase 3 · Xenon Pharmaceuticals Inc.
- Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder · Phase 2 · AbbVie
Neurology & pain (2 active studies)
- Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study · Stanford University
- GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study · W.L.Gore & Associates
Common conditions studied in Allentown
- Acute Myeloid Leukemia (8 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Major Depressive Disorder (5 active studies). Major depressive disorder research examines rapid-acting agents, augmentation strategies, and digital therapeutics for treatment-resistant cases.
- Anatomic Stage IV Breast Cancer AJCC v8 (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- B Acute Lymphoblastic Leukemia (4 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Acute Myeloid Leukemia Post Cytotoxic Therapy (3 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
Leading research sponsors in Allentown
- National Cancer Institute (NCI)
- Children's Oncology Group
- SWOG Cancer Research Network
- Memorial Sloan Kettering Cancer Center
- NRG Oncology
Local regulations and guidelines
Clinical trials in Pennsylvania are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Pennsylvania research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Allentown. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Allentown
Hipa.ai aggregates every recruiting study in Allentown from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Allentown?
There are approximately 139 recruiting clinical trials in Allentown, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Allentown pay participants?
Most recruiting trials in Allentown compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Allentown?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Allentown?
The most common conditions under active study in Allentown include Acute Myeloid Leukemia (8), Major Depressive Disorder (5), Anatomic Stage IV Breast Cancer AJCC v8 (4), B Acute Lymphoblastic Leukemia (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Allentown?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Allentown on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Allentown?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Allentown?
Recruiting research sites in Allentown include Lehigh Valley Hospital-Cedar Crest, Lehigh Valley Health Network, Saint Luke's Cancer Center - Allentown, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Allentown right now?
The largest active categories in Allentown are Cancer & tumors (84), Cardiovascular (7), Mental health & behavior (5). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.