Paid Clinical Trials in Erie, PA
As of June 2026, 94 paid clinical trials are recruiting in Erie, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Erie offers studies at sites including UPMC Hillman Cancer Center Erie for conditions such as Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Recurrent Endometrial Carcinoma, Amblyopia. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Erie
Trials by drug in Erie
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93 clinical trials
↓ Download CSVThe Effect of Osteopathic Manipulative Techniques on Human Tear Proteins
Study of ALK-001 on the Progression of Stargardt Disease
A Study in Adults With Geographic Atrophy
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration
A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)
A Clinical Study Evaluating Licaminlimab for Dry Eye Disease
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine
A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea
A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
A Study to Evaluate Safety and Efficacy of TP-05 in Healthy Participants With Tick Exposure
COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
A Multicenter, Randomized, Double-Masked, Placebo-Controlled Pilot Study to Evaluate the Efficacy and Safety of ZOC2017217 in Subjects With Age-Related Cataract
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer
A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 Months
Phase 2 Study of ADX-038 in Participants With Geographic Atrophy
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight
A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
A Phase 3 Clinical Trial to Compare RBS-001 to Eylea® in Subjects With Neovascular Age-Related Macular Degeneration
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK
Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE
E-Mindfulness Approaches for Living After Breast Cancer
Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer
High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer
Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)
Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
A Study to Evaluate the Efficacy and Safety of Orally Administered VX-01
A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy
About research studies in Erie
Erie has approximately 94 recruiting research studies across a wide range of therapeutic areas. Pennsylvania hosts UPenn's Perelman School of Medicine and Children's Hospital of Philadelphia — pioneers in CAR-T cell therapy — alongside UPMC, Thomas Jefferson University, and Penn State Hershey.
Top Research Study Locations in Erie
Researchers run research studies in Erie, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| UPMC Hillman Cancer Center Erie | Breast Cancer, Recurrent Endometrial Carcinoma, Anatomic Stage II Breast Cancer AJCC v8 | 43 |
| Saint Vincent Hospital | Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Stage IV Renal Cell Cancer AJCC v8 | 18 |
| Erie Retina Research | Geographic Atrophy, Macular Degeneration, Age-Related Macular Degeneration | 17 |
| Pediatric Ophthalmology of Erie | Amblyopia | 3 |
| Allegheny Health and Wellness Pavilion | Lyme Disease, Pneumococcal Disease | 2 |
| Central Erie Primary Care | Influenza, Lyme Disease | 2 |
| OB/GYN Associates of Erie | Endometrial Hyperplasia, Urinary Incontinence,Stress | 2 |
| UPMC Hamot | Previously Treated Non-Small Cell Lung Cancer, Pulmonary Embolism | 2 |
| ADARx Clinical Site | Geographic Atrophy Secondary to Age-related Macular Degeneration | 1 |
| AHN Saint Vincent Hospital | Pulmonary Embolism | 1 |
| Allegheny St. Vincent Hospital | Deep Venous Thrombosis, Post-Thrombotic Syndrome, Venous Thromboembolism | 1 |
| CBCC Global Research Site:002 | Age-related Wet Macular Degeneration | 1 |
| Erie | Endometriosis, Uterine Fibroids | 1 |
| Erie Retina Research LLC | Geographic Atrophy Secondary to Age-related Macular Degeneration | 1 |
| Erie Retina Research, LLC | Center Involved Diabetic Macular Edema, Diabetic Macular Edema | 1 |
| Erie Retina Research, LLC (Clinic) | Age - Related Macular Degeneration (AMD), Geographic Atrophy (GA) | 1 |
| Erie Retina Research, LLC - 300 State St | Diabetic Macular Edema | 1 |
| Erie Retinal Surgery & Erie Retina Research | Age-related Macular Degeneration (AMD), Geographic Atrophy (GA) | 1 |
| Erie, PA | Neovascular (Wet) Age-Related Macular Degeneration | 1 |
| Greater Erie Surgery Center | Lumbar Spinal Stenosis | 1 |
| Greater Erie Surgery Center, LLC | Lumbar Spinal Stenosis | 1 |
| OBGYN Associates of Erie | Functional Hypothalamic Amenorrhea (FHA) | 1 |
| Penn State Univercity | Anxiety, Depression, Stress | 1 |
| PennState the Beherend College/VAR Lab | Well-Being, Psychological | 1 |
| Plaza 38 Medical Offices | No Disease or Condition is Being Directly Studied, The Focus of the Study in Healthy Volunteers | 1 |
Active & Upcoming Studies in Erie (2026)
Recruiting trials in Erie grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (48 active studies)
- Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer · Phase 3 · National Cancer Institute (NCI)
- A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer · Phase 3 · National Cancer Institute (NCI)
Eye & vision (20 active studies)
- Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration · Phase 1, Phase 2 · Eyconis INC.
- A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME) · Phase 1 · Genentech, Inc.
Vaccines (3 active studies)
- A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine · Phase 3 · Pfizer
- A Study to Evaluate Safety and Efficacy of TP-05 in Healthy Participants With Tick Exposure · Phase 2 · Tarsus Pharmaceuticals, Inc.
Mental health & behavior (2 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Assessing the Impact of VR-Based Observational Mindfulness Meditation on Stress Reduction in Adults · Penn State University
Cardiovascular (2 active studies)
Common conditions studied in Erie
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Breast Cancer (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Recurrent Endometrial Carcinoma (4 active studies). ENT (otolaryngology) trials evaluate new treatments for hearing loss, swallowing disorders, and head and neck cancers — covering pharmacologic, surgical, and rehabilitative approaches.
- Amblyopia (3 active studies). Recruiting Amblyopia studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Diabetic Macular Edema (3 active studies). Recruiting Diabetic Macular Edema studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Geographic Atrophy (3 active studies). Recruiting Geographic Atrophy studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Erie
- National Cancer Institute (NCI)
- NRG Oncology
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- ECOG-ACRIN Cancer Research Group
Local regulations and guidelines
Clinical trials in Pennsylvania are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Pennsylvania research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Erie. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Erie
Hipa.ai aggregates every recruiting study in Erie from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Erie?
There are approximately 94 recruiting clinical trials in Erie, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Erie pay participants?
Most recruiting trials in Erie compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Erie?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Erie?
The most common conditions under active study in Erie include Anatomic Stage II Breast Cancer AJCC v8 (4), Breast Cancer (4), Recurrent Endometrial Carcinoma (4), Amblyopia (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Erie?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Erie on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Erie?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Erie?
Recruiting research sites in Erie include UPMC Hillman Cancer Center Erie, Saint Vincent Hospital, Erie Retina Research, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Erie right now?
The largest active categories in Erie are Cancer & tumors (48), Eye & vision (20), Vaccines (3). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.