A Study in Adults With Geographic Atrophy

Part of paid clinical trials in Bakersfield, California.

Sponsor
Sitala Bio LTD
Study ID
NCT07606365
Phase
PHASE2
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
60 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • STL303 — DRUG
    STL303 arm participants will receive a specific dose of STL303
  • Placebo — DRUG
    Placebo arm participants will receive placebo

Study Details

The purpose of this clinical research study is to look at how safe STL303 is and whether it works when given to people with Geographic Atrophy (GA) secondary to Age-related Macular Degeneration (AMD). Geographic atrophy secondary to AMD is a condition where cells in the back part of the eye slowly die, causing a blurry, or missing spot in the centre of vision.

Key Dates

Start date
Jun 30, 2026
Status verified
May 2026
Primary completion
Jul 31, 2028
Completion
Aug 31, 2029

Study Design

Enrollment
300 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: STL303 dose level 1
    Participants will receive STL303 dose level 1
  • Experimental: STL303 dose level 2
    Participants will receive STL303 dose level 2
  • Placebo Comparator: Placebo
    Participants will receive placebo

Primary Outcome Measure

Reduction of rate of total EZ area loss [ Time Frame: From baseline to Week 52 ]

Central Contacts

Locations (20)

FacilityCityStateZIPSite coordinators
California Retina ConsultantsBakersfieldCalifornia93309
Dilsher Dhoot (PRINCIPAL_INVESTIGATOR)
Retina-Vitreous Associates Medical GroupBeverly HillsCalifornia90211
Homayoun Tabandeh (PRINCIPAL_INVESTIGATOR)
Kaiser Permanente - OaklandOaklandCalifornia94612
Robin Vora (PRINCIPAL_INVESTIGATOR)
Retina Specialists of ColoradoAuroraColorado80012
Michael Jansen (PRINCIPAL_INVESTIGATOR)
Retina Group of New England, PCWaterfordConnecticut06385
Nauman Chaudhry (PRINCIPAL_INVESTIGATOR)
Retina Vitreous Associates of FloridaSt. PetersburgFlorida33711-
Florida Retina InstituteWildwoodFlorida34785
Luis Leon Alvarado (PRINCIPAL_INVESTIGATOR)
University Retina and Macula Associates, P.C.LemontIllinois60439-
Associated Vitreoretinal and Uveitis ConsultantsCarmelIndiana46032
Ramana Moorthy (PRINCIPAL_INVESTIGATOR)
Cumberland Valley Retina Consultants,P.C.HagerstownMaryland21740
Allen Hu (PRINCIPAL_INVESTIGATOR)
Mid Atlantic Retina SpecialistsHagerstownMaryland21740
Adam Gerstenblith (PRINCIPAL_INVESTIGATOR)
Ophthalmic Consultants of BostonWalthamMassachusetts02451
Chirag Shah (PRINCIPAL_INVESTIGATOR)
Long Island and Queens Vitreoretinal Consultants of NY, P.C.HauppaugeNew York11788
Brett Rosenblatt (PRINCIPAL_INVESTIGATOR)
Erie Retina ResearchEriePennsylvania16507
David Almeida (PRINCIPAL_INVESTIGATOR)
Tennessee Retina, PCNashvilleTennessee37203
Carl Awh (PRINCIPAL_INVESTIGATOR)
Retina Consultants of TexasBellaireTexas77401
David Brown (PRINCIPAL_INVESTIGATOR)
Star Vision ResearchBurlesonTexas76028
Courtney Crawford (PRINCIPAL_INVESTIGATOR)
Retina Consultants of TexasSchertzTexas78154
Jeremiah Brown (PRINCIPAL_INVESTIGATOR)
Northeast Wisconsin Retina AssociatesAppletonWisconsin54914
Swati Agarwal Sinha (PRINCIPAL_INVESTIGATOR)
Eye Clinic of WisconsinWausauWisconsin54403
Deepak Sambhara (PRINCIPAL_INVESTIGATOR)

Find similar trials in Bakersfield, CA

By condition
Age-related macular degeneration
By specialty
OphthalmologyRetina
By research site
California Retina Consultants· Bakersfield, CARetina-Vitreous Associates Medical Group· Beverly Hills, CAKaiser Permanente - Oakland· Oakland, CARetina Specialists of Colorado· Aurora, CORetina Group of New England, PC· Waterford, CTRetina Vitreous Associates of Florida· St. Petersburg, FL

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