As of June 2026, 71 paid clinical trials are recruiting in Harrisburg, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Harrisburg offers studies at sites including UPMC Pinnacle Cancer Center/Community Osteopathic Campus for conditions such as Breast Cancer, Heart Failure, Anatomic Stage II Breast Cancer AJCC v8, Head and Neck Squamous Cell Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Harrisburg has approximately 71 recruiting research studies across a wide range of therapeutic areas. Pennsylvania hosts UPenn's Perelman School of Medicine and Children's Hospital of Philadelphia — pioneers in CAR-T cell therapy — alongside UPMC, Thomas Jefferson University, and Penn State Hershey.
Researchers run research studies in Harrisburg, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| UPMC Pinnacle Cancer Center/Community Osteopathic Campus | Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Head and Neck Squamous Cell Carcinoma | 33 |
| Susquehanna Research Group | Ankylosing Spondylitis, Autoimmune Diseases, Birdshot Chorioretinitis | 4 |
| UPMC Pinnacle Harrisburg | Anatomic Stage IV Breast Cancer AJCC v8, Diastolic Heart Failure, Elevated CA15-3 or CEA or CA27-29 | 4 |
| Pinnacle Health Cardiovascular Institute | Heart Failure, Peripheral Vascular Diseases | 3 |
| UPMC Harrisburg | Pulmonary Embolism, Cardiovascular Diseases, Hypertension | 3 |
| UPMC Pinnacle Harrisburg Campus | Coronary Artery Disease, Mitral Valve Regurgitation, Tricuspid Regurgitation | 3 |
| Pennsylvania Psychiatric Institute | Anxiety, Chemically-Induced Disorders, Chronic Stress | 2 |
| Susquehanna Research Group, LLC | Celiac Disease, Moderately to Severely Active Crohn Disease | 2 |
| UPMC Pinnacle | Tricuspid Valve Disease, Cardiovascular Diseases, Heart Failure | 2 |
| Investigational | Crohn's Disease, Ulcerative Colitis | 2 |
| Home-based telemedicine | Chronic Granulomatous Disease (CGD) | 1 |
| Magee-Woman's Hospital | Locally Advanced Solid Tumors, Metastatic Solid Tumors, Recurrent Solid Tumors | 1 |
| Parents and Children Together (PACT) Lab Space | Anxiety Symptoms, Conduct Problems, Depressive Symptoms | 1 |
| Penn State Health Medical Group - Andrews Patel | Breast Cancer | 1 |
| Penn State Health Medical Group - Andrews Patel Hematology/Oncology East | Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma, RISS Stage II Plasma Cell Myeloma | 1 |
| Penn State Hershey Medical Center-TLC Research and Treatment Center | Problematic Sexual Behavior Among Preteen Children | 1 |
| PennState Hershey Medical Center--PennState Health Children's Hospital | Hypoplastic Left Heart Syndrome (HLHS) | 1 |
| Pinnacle Transplant Associates | Development of Reporting System for Molecular Diagnosis, Incorporate Molecular Diagnosis Into Diagnostic Standards, Validation Study of Molecular Diagnostic System | 1 |
| Susquehanna Research Group - Gastroenterology | C. Diff Infection, C.Difficile Diarrhea, CDI | 1 |
| Susquehanna Valley Pain Management | Lumbar Spinal Stenosis | 1 |
| UPMC Heart & Vascular Institute | Mitral Valve Insufficiency | 1 |
| UPMC Hillman Cancer Center - Pinnacle (Community Osteopathic / Medical Sciences Pavillion) | Colorectal Neoplasms | 1 |
| Univ of Pittsburg Med Ctr Pinnacle | Early Breast Cancer | 1 |
| University of Pittsburg Medical Center - Harrisburg | Distal Femur Fracture | 1 |
| University of Pittsburgh Medical Center | Kidney Transplant Rejection | 1 |
Recruiting trials in Harrisburg grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in Pennsylvania are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Pennsylvania research additionally follows state public health department oversight and any applicable state privacy statutes.
Hipa.ai aggregates every recruiting study in Harrisburg from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 71 recruiting clinical trials in Harrisburg, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Harrisburg compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Harrisburg include Breast Cancer (5), Heart Failure (4), Anatomic Stage II Breast Cancer AJCC v8 (3), Head and Neck Squamous Cell Carcinoma (3), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Harrisburg on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Harrisburg include UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Susquehanna Research Group, UPMC Pinnacle Harrisburg, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Harrisburg are Cancer & tumors (37), Cardiovascular (8), Mental health & behavior (4). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.