Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,674 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

Filter results

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

3,674 clinical trials

↓ Download CSV

Neoadjuvant Pembrolizumab and Lenvatinib for Renal Cell Carcinoma

for Renal Cell Carcinoma

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05733715·EARLY_Phase 1·Recruiting

Apply to this trial

Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

for Major Depressive Disorder

24 locations incl. Huntsville

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 18 - 65

Code: NCT05850689·Phase 3·Recruiting

Apply to this trial

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

for Episodic Migraine

Drug: Atogepant

42 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT05711394·Phase 3·Recruiting

Apply to this trial

The Ailliance Post-Market Clinical Study

for Spinal Deformity

22 locations incl. Tucson

Sponsor: Medtronic Spinal and Biologics

Sex: All·Age: 18+

Code: NCT05856370·Recruiting

Apply to this trial

Platform of Randomized Adaptive Clinical Trials in Critical Illness

for Respiratory Insufficiency

26 locations incl. Tucson

Sponsor: University Health Network, Toronto

Sex: All·Age: 18+

Code: NCT05440851·Recruiting

Apply to this trial

Comparison of Transforming Powder Dressing to NPIAP Recommended Standard of Care Therapies in Stage 2, 3 and 4 Pressure Injuries

for Pressure Ulcers Stage II

14 locations incl. San Diego

Sponsor: ULURU Inc.

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT05496296·Recruiting

Apply to this trial

Empathic Communication Skills (ECS) Training

for Lung Cancer

12 locations incl. Irvine

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT05456841·Recruiting

Apply to this trial

A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

for Metastatic Castration-resistant Prostate Neoplasms

Drug: Pasritamig

7 locations incl. Sarasota

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT05818683·Phase 1·Recruiting

Apply to this trial

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

for Recurrent Endometrial Carcinoma

Drug: Selumetinib

293 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05554328·Phase 2·Recruiting

Apply to this trial

An Open-label Study of XEN1101 in Epilepsy

for Focal Epilepsy

53 locations incl. Phoenix

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 12+

Code: NCT05718817·Phase 3·Enrolling By Invitation

Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for Cystic Fibrosis

59 locations incl. Birmingham

Sponsor: Chris Goss

Sex: All·Age: 6+

Code: NCT05548283·Phase 4·Recruiting

Apply to this trial

ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer

for Ovarian Cancer

1 location in Pittsburgh

Sponsor: Alexander B Olawaiye, MD

Sex: Female·Age: 18+

Code: NCT05071937·Phase 2·Recruiting

Apply to this trial

Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)

for Tachycardia, Ventricular

11 locations incl. Los Angeles

Sponsor: Varian, a Siemens Healthineers Company

Sex: All·Age: 18+

Code: NCT05765175·Recruiting

Apply to this trial

Prophylaxis With Direct-acting Antivirals for Kidney Transplantation From HCV-Infected Donors to Uninfected Recipients

for HCV

9 locations incl. La Jolla

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05653232·Recruiting

Apply to this trial

VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

for Solid Tumor

Drug: Atezolizumab

7 locations incl. Chicago

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 6 Months - 30

Code: NCT04796012·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study to Investigate the Safety, Tolerability, and Efficacy of BxC-I17e Single and Multiple Dose SC Injection in Patients With Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis

3 locations incl. North Little Rock

Sponsor: Brexogen Inc.

Sex: All·Age: 18+

Code: NCT06055361·Phase 1·Recruiting

Apply to this trial

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

for Heart Diseases

42 locations incl. Los Angeles

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18+

Code: NCT04124120·Recruiting

Apply to this trial

Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury

for Acute Kidney Injury

38 locations incl. Birmingham

Sponsor: SeaStar Medical

Sex: All·Age: 18+

Code: NCT05758077·Recruiting

Apply to this trial

SEEG-Guided DBS for OCD

for Obsessive-Compulsive Disorder

2 locations incl. Stanford

Sponsor: Casey H. Halpern, M.D.

Sex: All·Age: 22 - 75

Code: NCT05623306·Recruiting

Apply to this trial

Cervical Ripening as an Outpatient Method Using the Foley (COMFORT)

for Induction of Labor Affected Fetus / Newborn

6 locations incl. Newark

Sponsor: University of Pennsylvania

Sex: Female·Age: 18 - 60·Accepts healthy volunteers

Code: NCT05759988·Recruiting

Apply to this trial

Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer

for Prostate Cancer

5 locations incl. Duarte

Sponsor: Varian, a Siemens Healthineers Company

Sex: Male·Age: 18+

Code: NCT05804318·Recruiting

Apply to this trial

Exenatide Pharmacokinetics and Pharmacodynamics in Gestational Diabetes

for Gestational Diabetes

1 location in Pittsburgh

Sponsor: Maisa N. Feghali, MD

Sex: Female·Age: 18 - 50

Code: NCT05482789·Phase 4·Recruiting

Apply to this trial

Task Switching Between Target Templates During Visual Search in Healthy Adults

for Healthy

1 location in Bethlehem

Sponsor: Lehigh University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05709743·Enrolling By Invitation

Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

for Neurotrophic Keratopathy

29 locations incl. Laguna Hills

Sponsor: ReGenTree, LLC

Sex: All·Age: 18+

Code: NCT05555589·Phase 3·Recruiting

Apply to this trial

Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant

for Pre-Bronchiolitis Obliterans Syndrome

20 locations incl. Phoenix

Sponsor: Renovion, Inc.

Sex: All·Age: 18 - 75

Code: NCT05654922·Phase 3·Recruiting

Apply to this trial

Distal Radius Interventions for Fracture Treatment

for Fracture Distal Radius

25 locations incl. Phoenix

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 4 - 10

Code: NCT05131685·Recruiting

Apply to this trial

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

475 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting

Apply to this trial

Pain and Disability Outcomes in Post Amputation Patients

for Limb Pain, Phantom

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 89

Code: NCT05716321·Recruiting

Apply to this trial

Extracorporeal Photopheresis in Sezary Syndrome

for Sezary Syndrome

3 locations incl. Atlanta

Sponsor: Oleg E. Akilov, MD, PhD

Sex: All·Age: 18 - 100

Code: NCT05157581·Recruiting

Apply to this trial

Linking Brain Network Dynamics to Imminent Smoking Lapse Risk and Behavior

for Smoking

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT05572671·Recruiting

Apply to this trial

Optimizing Tracheal Intubation Outcomes and Neonatal Safety

for Infant

7 locations incl. Little Rock

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 1

Code: NCT05838690·Recruiting

Apply to this trial

Testing Strategies to Improve Substance Misuse Prevention Research Use in State Policy Contexts

for Substance Abuse

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06856148·Recruiting

Apply to this trial

Second Window Indocyanine Green for All Nervous System Tumors

for Nervous System Tumor

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT05746104·Phase 1·Enrolling By Invitation

Ultrasound Guided Serratus Anterior Plane Block for Rib Fractures

for Rib Fracture Multiple

1 location in York

Sponsor: WellSpan Health

Sex: All·Age: 18+

Code: NCT05748366·Recruiting

Apply to this trial

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

for Breast Cancer, Early Breast Cancer

Drug: Camizestrant

127 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT05774951·Phase 3·Recruiting

Apply to this trial

SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma

for Ovarian Cancer

5 locations incl. Tampa

Sponsor: Verismo Therapeutics

Sex: All·Age: 18+

Code: NCT05568680·Phase 1·Recruiting

Apply to this trial

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

for Metastatic Melanoma

Drug: Lifileucel

22 locations incl. Birmingham

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT05727904·Phase 3·Recruiting

Apply to this trial

Cannabis Use and Outcomes in Black and White Patients With Cancer

for Cancer

3 locations incl. Buffalo

Sponsor: State University of New York at Buffalo

Sex: All·Age: 21 - 99

Code: NCT06037681·Recruiting

Apply to this trial

Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms

for T-Cell Neoplasm

Drug: Pacritinib

6 locations incl. Duarte

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18+

Code: NCT04858256·Phase 2·Recruiting

Apply to this trial

Home Apnea Testing in CHildren Trial

for Sleep Apnea, Obstructive

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 5 - 12

Code: NCT05382754·Recruiting

Apply to this trial