Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,674 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

Filter results

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

3,674 clinical trials

↓ Download CSV

Implementation and Evaluation of A Health Innovation to Support Medicaid-Insured Individuals Following Hospitalization

for Care Transitions

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 99

Code: NCT05714605·Enrolling By Invitation

Hands and Hearts Together

for Parent-Child Relations

2 locations incl. College Park

Sponsor: University of Maryland, College Park

Sex: All·Age: 8 Months+·Accepts healthy volunteers

Code: NCT05834907·Recruiting

Apply to this trial

Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts

for Breast Cancer

10 locations incl. Birmingham

Sponsor: American College of Radiology

Sex: Female·Age: 45 - 74·Accepts healthy volunteers

Code: NCT05625659·Recruiting

Apply to this trial

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

for Geographic Atrophy

15 locations incl. Beverly Hills

Sponsor: Genentech, Inc.

Sex: All·Age: 50+

Code: NCT05626114·Phase 2·Recruiting

Apply to this trial

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

for HIV Infection

11 locations incl. La Jolla

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 45 - 80

Code: NCT04949464·Recruiting

Apply to this trial

Applying pGz in Mitochondrial Disease

for Mitochondrial Myopathies

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 60·Accepts healthy volunteers

Code: NCT05569122·Phase 1·Recruiting

Apply to this trial

Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

for Lymphoma

45 locations incl. Tuscaloosa

Sponsor: University of Rochester

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05006482·Phase 3·Recruiting

Apply to this trial

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

for Recurrent Glioblastoma, IDH-Wildtype

Drug: Selinexor

36 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05432804·Phase 1, Phase 2·Recruiting

Apply to this trial

TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients

for Breast Cancer

3 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 65+

Code: NCT05535192·Recruiting

Apply to this trial

Music Listening: A Mechanistic Trial

for Critical Illness

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 2 Months - 17

Code: NCT05541029·Recruiting

Apply to this trial

A Prospective Natural History Study of Lymphatic Anomalies

for Lymphatic Diseases

2 locations incl. Bethesda

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All·Age: 1 Day - 100·Accepts healthy volunteers

Code: NCT05731141·Recruiting

Apply to this trial

Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)

for Von Willebrand Diseases

10 locations incl. Los Angeles

Sponsor: Vega Therapeutics, Inc

Sex: All·Age: 12 - 60·Accepts healthy volunteers

Code: NCT05776069·Phase 1, Phase 2·Recruiting

Apply to this trial

Observational Study Protocol: LIVER-R

for Hepatobiliary Cancers

21 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06252753·Recruiting

Apply to this trial

Vivistim Registry for Paired VNS Therapy (GRASP)

for Upper Extremity Problem

15 locations incl. Orlando

Sponsor: MicroTransponder Inc.

Sex: All·Age: 22+

Code: NCT05301140·Recruiting

Apply to this trial

Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)

for Gastric or Gastroesophageal Junction Adenocarcinoma

11 locations incl. Duarte

Sponsor: Phanes Therapeutics

Sex: All·Age: 18+

Code: NCT05482893·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition

for Primary Immune Regulatory Disorder

13 locations incl. San Francisco

Sponsor: Joseph Oved

Sex: All·Age: All ages

Code: NCT05787574·Phase 2·Recruiting

Apply to this trial

Iron Replacement to Reduce Anemia During Neoadjuvant Chemotherapy

for Anemia

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT05800600·Phase 2·Recruiting

Apply to this trial

Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)

for Alzheimer's Disease

2 locations incl. Boston

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 120

Code: NCT05658913·Recruiting

Apply to this trial

A Study of PYX-201 in Advanced Solid Tumors

for Solid Tumor

17 locations incl. Scottsdale

Sponsor: Pyxis Oncology, Inc

Sex: All·Age: 18+

Code: NCT05720117·Phase 1·Recruiting

Apply to this trial

Lymphoscintigraphy Directed Elective Neck Radiation for p16+ Favorable Risk Oropharynx Cancer

for Oropharynx Cancer

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT05800574·Phase 2·Recruiting

Apply to this trial

Reducing Patient Memory Recall in the Burning Mouth Patient Population

for Burning Mouth Syndrome

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05819697·Recruiting

Apply to this trial

Frailty in Patients With Gastrointestinal Cancer Who Are Undergoing Major Surgery

for Gastrointestinal Cancer

2 locations incl. East Corning

Sponsor: The Guthrie Clinic

Sex: All·Age: 18+

Code: NCT05694338·Recruiting

Apply to this trial

An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter Disease

for Vanishing White Matter Disease

3 locations incl. Boston

Sponsor: Calico Life Sciences LLC

Sex: All·Age: 6 Months+

Code: NCT05757141·Phase 1, Phase 2·Recruiting

Apply to this trial

Prognostication of Recovery in Early Disorders of Consciousness Study

for Disorder of Consciousness

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07074678·Enrolling By Invitation

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for Alpha1-Antitrypsin Deficiency

37 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT05677971·Phase 3·Recruiting

Apply to this trial

iMmune SignAtures and Clinical outComes in AP

for Acute Pancreatitis

5 locations incl. Los Angeles

Sponsor: Ohio State University

Sex: All·Age: 18 - 75

Code: NCT05878236·Recruiting

Apply to this trial

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

for Metastatic Salivary Gland Carcinoma

150 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05408845·Phase 2·Recruiting

Apply to this trial

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

for High Grade Osteosarcoma

Drug: Cabozantinib

177 locations incl. Charlottesville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 40

Code: NCT05691478·Phase 2, Phase 3·Recruiting

Apply to this trial

A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies

for Advanced or Metastatic Solid Tumors

11 locations incl. Scottsdale

Sponsor: Incendia Therapeutics

Sex: All·Age: 18+

Code: NCT05753722·Phase 1·Recruiting

Apply to this trial

The GORE® VIABAHN® FORTEGRA Venous Stent Iliofemoral Study

for Venous Thromboses

27 locations incl. Stanford

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT05489588·Recruiting

Apply to this trial

FTT PET/CT in Metastatic Prostate Cancer

for Prostate Cancer Metastatic

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Male·Age: 18+

Code: NCT05242744·Recruiting

Apply to this trial

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

for Adenocarcinoma of Lung

6 locations incl. Beverly Hills

Sponsor: Lantern Pharma Inc.

Sex: All·Age: 18+

Code: NCT05456256·Phase 2·Recruiting

Apply to this trial

Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC

for Thyroid Cancer

6 locations incl. Washington D.C.

Sponsor: Massachusetts General Hospital

Sex: All·Age: 12+

Code: NCT05668962·Phase 2·Recruiting

Apply to this trial

Longitudinal Study for Central Nervous System Vasculitis

for Central Nervous System Vasculitis

4 locations incl. Rochester

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05734404·Recruiting

Apply to this trial

HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets

for Heart Failure

6 locations incl. Sacramento

Sponsor: Northwestern University

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT05873634·Recruiting

Apply to this trial

A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

for Areata Alopecia

Drug: Baricitinib

44 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 - 17

Code: NCT05723198·Phase 3·Recruiting

Apply to this trial

Collection of Circulating Biomarkers in Pancreatic Cancer

for Pancreas Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT05743049·Recruiting

Apply to this trial

Effect of Raised End-Tidal pCo2 on Choroidal Volume

for Intraocular Pressure

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: Up to 8·Accepts healthy volunteers

Code: NCT06275308·Recruiting

Apply to this trial

Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

for Acute Myeloid Leukemia

9 locations incl. Phoenix

Sponsor: Norman J. Lacayo

Sex: All·Age: Up to 21

Code: NCT05101551·Phase 1·Recruiting

Apply to this trial

Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors

for Lymphoblastic Leukemia

3 locations incl. Duarte

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 30

Code: NCT05194397·Phase 2·Recruiting

Apply to this trial