HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets

Part of paid clinical trials in Sacramento, California.

Sponsor
Northwestern University
Study ID
NCT05873634
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
30 Years - N/A
Healthy Volunteers
Accepted

Study Details

HeartShare is a comprehensive study of heart failure, a common and serious medical condition which occurs when the heart is unable to keep up with the demands of the body, resulting in shortness of breath, fluid retention, and fatigue. HeartShare aims to better classify heart failure into subtypes to help develop more personalized treatments for patients, with the hope that this will improve the lives of heart failure patients. To do this, HeartShare is bringing together a large amount of data (including images, such as heart ultrasounds and MRIs and molecular data from the blood, such as genetics) from previously conducted studies and electronic health records, and is gathering new data through participants enrolled in the HeartShare Deep Phenotyping Study.

Key Dates

Start date
Mar 1, 2023
Status verified
Apr 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
1,000 participants (estimated)

Arms

  • Arm: HFpEF
    Participants with HFpEF
  • Arm: Non-HFpEF
    Participants without HFpEF

Primary Outcome Measure

Number of participants with Heart Failure with Preserved Ejection Fraction (HFpEF) [ Time Frame: Up to 5 years ]

Central Contacts

Locations (6)

FacilityCityStateZIPSite coordinators
University of California DavisSacramentoCalifornia95817
Maiya Her
916-734-0230
Nipavan Chiamvimonvat, MD (PRINCIPAL_INVESTIGATOR)
Javier Lopez, MD (SUB_INVESTIGATOR)
Martin Cadeiras, MD (SUB_INVESTIGATOR)
Northwestern UniversityChicagoIllinois60611
Laura Alagna
[email protected]
312-695-6765
Sadiya Khan, MD (PRINCIPAL_INVESTIGATOR)
Laura Rasmussen-Torvik, PhD, MPH (PRINCIPAL_INVESTIGATOR)
Mass General BrighamBostonMassachusetts02114
Diane Cocca-Spofford
[email protected]
617-726-8228
Greg Lewis, MD (PRINCIPAL_INVESTIGATOR)
Akshay Desai, MD, MPH (SUB_INVESTIGATOR)
Michael Givertz, MD (SUB_INVESTIGATOR)
Scott Solomon, MD (SUB_INVESTIGATOR)
Mayo ClinicRochesterMinnesota55905
Matthew Adolphsen
[email protected]
507-422-5919
Barry Borlaug, MD (PRINCIPAL_INVESTIGATOR)
Margaret Redfield, MD (SUB_INVESTIGATOR)
Wake Forest UniversityWinston-SalemNorth Carolina27157
Ben Nelson
336-716-6789
Dalane Kitzman, MD (PRINCIPAL_INVESTIGATOR)
Alain Bertoni, MD, MPH (SUB_INVESTIGATOR)
University of PennsylvaniaPhiladelphiaPennsylvania19104
Tiffany Sharkoski
215-615-2354
Julio Chirinos, MD, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Sacramento, CA

By condition
Heart failure
By specialty
CardiologyHeart disease
By research site
University of California Davis· Sacramento, CANorthwestern University· Chicago, ILMass General Brigham· Boston, MAMayo Clinic· Rochester, MNWake Forest University· Winston-Salem, NCUniversity of Pennsylvania· Philadelphia, PA

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