Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,674 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,674 clinical trials

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Synovial Sarcoma Registry / Biospecimen Repository

for Synovial Sarcoma

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT05910307·Recruiting

Apply to this trial

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

for Crohn Disease

22 locations incl. Phoenix

Sponsor: Connecticut Children's Medical Center

Sex: All·Age: 6 - 17

Code: NCT05781152·Phase 4·Recruiting

Apply to this trial

Alzheimer's Disease Neuroimaging Initiative 4

for Mild Cognitive Impairment

59 locations incl. Birmingham

Sponsor: University of Southern California

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05617014·Enrolling By Invitation

Study of ALTO-300 in MDD

for Major Depressive Disorder

45 locations incl. Phoenix

Sponsor: Alto Neuroscience

Sex: All·Age: 18 - 70

Code: NCT05922878·Phase 2·Recruiting

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Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease

for Sickle Cell Disease

9 locations incl. Birmingham

Sponsor: RTI International

Sex: All·Age: 18+

Code: NCT06385886·Recruiting

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A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

for Cancer

11 locations incl. Los Angeles

Sponsor: Conjupro Biotherapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05948865·Phase 1·Recruiting

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SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for Glioma

40 locations incl. Birmingham

Sponsor: Nuvation Bio Inc.

Sex: All·Age: 18+

Code: NCT05303519·Phase 3·Recruiting

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Human Learning of New Structured Information Across Time and Sleep

for Learning

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT05910762·Recruiting

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An Augmented Reality Based System for Neglect Detection, Assessment, and Rehabilitation

for Stroke

2 locations incl. Boston

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04187131·Recruiting

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Evaluating the Safety and Efficacy of Polyethylene Glycol (PEG) Mediated Fusion (PEG Fusion)

for Peripheral Nerve Injuries

7 locations incl. Baltimore

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 80

Code: NCT04789044·Phase 2·Recruiting

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MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

for Recurrent Melanoma (Skin)

Drug: Nivolumab

13 locations incl. Orange

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT05655312·Phase 1, Phase 2·Recruiting

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Amygdala Neurofeedback for Depression - Large Scale Clinical Trial

for Major Depressive Disorder

1 location in Pittsburgh

Sponsor: Kymberly Young

Sex: All·Age: 18 - 55

Code: NCT05703256·Recruiting

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Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancer

for Metastatic Pancreatic Cancer

6 locations incl. Los Angeles

Sponsor: Cantex Pharmaceuticals

Sex: All·Age: 18 - 80

Code: NCT05766748·Phase 1, Phase 2·Recruiting

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Liposomal Bupivacaine and Transoral Robotic Surgery

for Oropharyngeal Cancer

1 location in Danville

Sponsor: Geisinger Clinic

Sex: All·Age: 18+

Code: NCT05862792·Recruiting

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ML-004 Open-Label Extension Study in Adults and Adolescents With Autism Spectrum Disorders (ASD)

for Autism Spectrum Disorder

18 locations incl. Dothan

Sponsor: MapLight Therapeutics

Sex: All·Age: 12 - 46

Code: NCT05889273·Phase 2·Enrolling By Invitation

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

for Heart Failure

20 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 29 Days - 17

Code: NCT05714085·Phase 2, Phase 3·Recruiting

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PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

for Infections

13 locations incl. Indianapolis

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18+

Code: NCT05699174·Phase 3·Recruiting

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Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck

for Aortic Aneurysm, Abdominal

16 locations incl. Washington

Sponsor: Rijnstate Hospital

Sex: All·Age: 18+

Code: NCT05484115·Recruiting

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Using Smartphones to Improve Physical Activity Levels of Individuals With Spinal Cord Injury

for Spinal Cord Injuries

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18 - 75

Code: NCT05317832·Phase 2·Recruiting

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GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma

for Refractory Neuroblastoma

1 location in Philadelphia

Sponsor: Stephan Grupp MD PhD

Sex: All·Age: 1+

Code: NCT05650749·Phase 1·Recruiting

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QOL and Sarcopenia in Patients With Ascites

for Ascites Hepatic

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT05726747·Recruiting

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Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

for Refractory Ewing Sarcoma

Drug: Lurbinectedin

14 locations incl. Los Angeles

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 2 - 30

Code: NCT05734066·Phase 1, Phase 2·Recruiting

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FOG-001 in Locally Advanced or Metastatic Solid Tumors

for Cancer

31 locations incl. Phoenix

Sponsor: Parabilis Medicines, Inc.

Sex: All·Age: 18+

Code: NCT05919264·Phase 1, Phase 2·Recruiting

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Targeted Immunotherapy After Myeloablative TBI-Based Conditioning & AlloHCT in CAYA With High Risk T-Cell ALL & Lymphoma

for T-cell Acute Lymphoblastic Leukemia

16 locations incl. Phoeniz

Sponsor: New York Medical College

Sex: All·Age: Up to 39

Code: NCT04972942·Phase 1·Recruiting

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Phase IB/II of CPX-351 for Relapse Prevention in AML

for Acute Myeloid Leukemia (AML) in Remission

3 locations incl. Washington D.C.

Sponsor: Georgetown University

Sex: All·Age: 18+

Code: NCT04990102·Phase 1, Phase 2·Recruiting

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Randomized Assessment of TcMS for VT Storm

for Ventricular Tachycardia

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05599022·Recruiting

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A Study to Understand How the Study Medicine (PF-06823859) Works in People With Active Idiopathic Inflammatory Myopathies [Dermatomyositis (DM) and Polymyositis (PM)]

for Myositis

47 locations incl. Glendale

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT05895786·Phase 3·Recruiting

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MASA Valve Early Feasibility Study

for Tetrology of Fallot

5 locations incl. Peoria

Sponsor: PECA Labs

Sex: All·Age: 0 - 22

Code: NCT05452720·Recruiting

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A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)

for Esophageal Squamous Cell Carcinoma

5 locations incl. Tucson

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT05319730·Phase 1, Phase 2·Recruiting

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A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

for Ulcerative Colitis

22 locations incl. Mobile

Sponsor: Takeda

Sex: All·Age: 2+

Code: NCT05442567·Phase 3·Recruiting

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Comparing Direct vs Indirect Methods for Cascade Screening

for Long QT Syndrome

1 location in Lancaster

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT05348564·Recruiting

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Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

for Osteomyelitis Tibia

14 locations incl. Gainesville

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05421741·Phase 4·Recruiting

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Vismodegib Combined With Atezolizumab in Platinum Resistant Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

for Platinum-Resistant Fallopian Tube Carcinoma

Drug: Atezolizumab

1 location in Pittsburgh

Sponsor: Ronald Buckanovich

Sex: Female·Age: 18+

Code: NCT05538091·Phase 2·Recruiting

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Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

for Inherited Retinal Degeneration

19 locations incl. Little Rock

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4+

Code: NCT05589714·Recruiting

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A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Drug: Nivolumab

390 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 5 - 60

Code: NCT05675410·Phase 3·Recruiting

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XTX301 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

11 locations incl. Sacramento

Sponsor: Xilio Development, Inc.

Sex: All·Age: 18+

Code: NCT05684965·Phase 1, Phase 2·Recruiting

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Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

for Relapsed Non-Hodgkin Lymphoma

32 locations incl. Irvine

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT05826535·Phase 1, Phase 2·Recruiting

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A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation

for Heart Failure

Drug: Ziltivekimab

184 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT05636176·Phase 3·Recruiting

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A Non-interventional, International, Multicentre Clinical Research Study to Build the Largest Collection of Multimodal Data (Including Clinical Data, Imaging Data and Omics Data) in Oncology

for Diffuse Large B Cell Lymphoma

1 location in Pittsburgh

Sponsor: OWKIN

Sex: All·Age: 18+

Code: NCT06625203·Recruiting

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Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

454 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642572·Phase 2·Recruiting

Apply to this trial