Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,674 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,674 clinical trials

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Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer

for Breast Cancer

8 locations incl. Columbia

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT05748834·Phase 2·Recruiting

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A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors

for Solid Tumors

11 locations incl. Los Angeles

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05836324·Phase 1·Recruiting

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Restoring Spindle and Thalamocortical Efficiency in Early-Course Schizophrenia Patients Using Auditory Stimulation

for Schizophrenia

1 location in Pittsburgh

Sponsor: Fabio Ferrarelli

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT05956951·Recruiting

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Study of Biodistribution, Metabolism, Excretion and Brain Uptake of 11C-HY-2-15

for Tauopathies

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 40 - 80·Accepts healthy volunteers

Code: NCT06032026·EARLY_Phase 1·Recruiting

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CW2IP2: Imaging and Diagnostic Assessments

for Tauopathies

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 40 - 85·Accepts healthy volunteers

Code: NCT06083467·Recruiting

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A Study to Evaluate the Safety, Efficacy, PK, PD and Immunogenicity of Cipaglucosidase Alfa/Miglustat in IOPD Subjects Aged 0 to <18

for Glycogen Storage Disease Type II Infantile Onset

6 locations incl. Gainesville

Sponsor: Amicus Therapeutics

Sex: All·Age: Up to 17

Code: NCT04808505·Phase 3·Recruiting

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A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

for Acute Myeloid Leukemia

Drug: Venetoclax

44 locations incl. Phoenix

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05735184·Phase 1·Recruiting

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

40 locations incl. Birmingham

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting

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Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients

for Psoriatic Arthritis

Drug: Guselkumab

14 locations incl. Loxahatchee Groves

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 80

Code: NCT05669833·Phase 3·Recruiting

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Project e-PBI+ - Parent Intervention to Reduce College Student Drinking and Cannabis Use

for Underage Drinking

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 18 - 19·Accepts healthy volunteers

Code: NCT05345951·Recruiting

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

93 locations incl. Phoenix

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting

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Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care

for Suicide

3 locations incl. Pittsburgh

Sponsor: Elizabeth Arnold

Sex: All·Age: 18 - 24

Code: NCT05869552·Recruiting

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Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for Locally Advanced Lung Non-Small Cell Carcinoma

470 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05624996·Phase 3·Recruiting

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A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

for Non-small Cell Lung Cancer

18 locations incl. Gilbert

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05877599·Phase 1·Recruiting

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24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

for Chronic Spontaneous Urticaria

12 locations incl. Bakersfield

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 17

Code: NCT05677451·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe Asthma

for Moderate to Severe Asthma

Drug: Povorcitinib

26 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18 - 65

Code: NCT05851443·Phase 2·Recruiting

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Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)

for Familial Adenomatous Polyposis

17 locations incl. Scottsdale

Sponsor: Recursion Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT05552755·Phase 1, Phase 2·Recruiting

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Autologous Dendritic Cell Vaccine in Kidney Cancer

for Carcinoma, Renal Cell

1 location in Pittsburgh

Sponsor: Jodi Maranchie

Sex: All·Age: 18+

Code: NCT05127824·Phase 2·Recruiting

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Limited-duration Teclistamab

for Myeloma Multiple

Drug: Teclistamab

5 locations incl. Little Rock

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT05932680·Phase 2·Recruiting

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Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks

for Pain, Chronic

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT05961800·Recruiting

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In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and Paraganglioma

for Pheochromocytoma

1 location in Philadelphia

Sponsor: Heather Wachtel

Sex: All·Age: 18+

Code: NCT05636540·EARLY_Phase 1·Recruiting

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Pregnancy 24/7 Offspring Study

for Healthy

3 locations incl. Iowa City

Sponsor: Kara Whitaker

Sex: All·Age: 0 - 47·Accepts healthy volunteers

Code: NCT07172880·Recruiting

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Study of ART6043 in Advanced/Metastatic Solid Tumors Patients (POLKA)

for Advanced Solid Tumor

7 locations incl. Grand Rapids

Sponsor: Artios Pharma Ltd

Sex: All·Age: 18+

Code: NCT05898399·Phase 1, Phase 2·Recruiting

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Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

for Lymphoid Leukemia

22 locations incl. Tucson

Sponsor: Stanford University

Sex: All·Age: Up to 26

Code: NCT05865301·Recruiting

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ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors

for Non Small Cell Lung Cancer

46 locations incl. Dothan

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT05671510·Phase 3·Recruiting

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A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

for Chronic Obstructive Pulmonary Disease

68 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 40 - 90

Code: NCT05878769·Phase 3·Recruiting

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Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study

for Friedreich Ataxia

9 locations incl. Los Angeles

Sponsor: Friedreich's Ataxia Research Alliance

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06016946·Recruiting

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The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency or ABCC6 Deficiency

for Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency

5 locations incl. San Diego

Sponsor: Inozyme Pharma

Sex: All·Age: Up to 1

Code: NCT05734196·Phase 1·Recruiting

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A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

Drug: Iberdomide

44 locations incl. Aurora

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT05827016·Phase 3·Recruiting

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A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

for Hidradenitis Suppurativa

Drug: Upadacitinib

87 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 12+

Code: NCT05889182·Phase 3·Recruiting

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Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers

for Diabetic Foot Ulcer

30 locations incl. Mesa

Sponsor: Piomic Medical

Sex: All·Age: 22 - 90

Code: NCT05758545·Recruiting

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Characterization of Gastric Evoked Potentials

for Healthy

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 21 - 60·Accepts healthy volunteers

Code: NCT05924009·Recruiting

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A Retrospective Study to Characterize Participants With Propionic Acidemia

for Propionic Acidemia

6 locations incl. Stanford

Sponsor: ModernaTX, Inc.

Sex: All·Age: 2+

Code: NCT05769621·Recruiting

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Safety and Tolerability Subretinal OPGx-001 for LCA5-Associated Inherited Retinal Degeneration (LCA5-IRD) and Non-interventional Arm With Untreated Patients

for LCA5

2 locations incl. Philadelphia

Sponsor: Opus Genetics, Inc

Sex: All·Age: 4+

Code: NCT05616793·Phase 1, Phase 2·Recruiting

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DFC 004 Biomarkers for Active Diabetic Foot Ulcers

for Diabetic Foot Ulcer

8 locations incl. Tucson

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06104969·Recruiting

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Neuro-affective Response to Light in Depressed Adolescents and Young Adults

for Depression in Adolescence

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 12 - 30

Code: NCT05712772·Recruiting

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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

820 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting

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A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia

for Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands

18 locations incl. Gilbert

Sponsor: MeiraGTx, LLC

Sex: All·Age: 18+

Code: NCT05926765·Phase 2·Recruiting

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Reducing Alcohol Involved Sexual Violence in Higher Education

for Sexual Violence

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 24·Accepts healthy volunteers

Code: NCT05185440·Recruiting

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Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

for Diffuse Large B-Cell Lymphoma

87 locations incl. Tucson

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05633615·Phase 2·Recruiting

Apply to this trial