RecruitingPhase 3Drug trialPulmonary Embolism - Thrombus Removal With Catheter-Directed TherapyPE-TRACT is an open-label, assessor-blinded, randomized trial, aiming to compare catheter-directed therapy (CDT) and anticoagulation (CDT group) with anticoagulation alone (No-CDT) in 500 patients with submassive PE, proximal pulmonary artery thrombus and right ventricular dilation.