Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,656 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,656 clinical trials

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Periprosthetic Joint Infection Bubble Study

for Periprosthetic Joint Infection (PJI)

2 locations incl. Pittsburgh

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07599865·Phase 2·Not Yet Recruiting

A Study in Adults With Geographic Atrophy

for Geographic Atrophy

20 locations incl. Bakersfield

Sponsor: Sitala Bio LTD

Sex: All·Age: 60+

Code: NCT07606365·Phase 2·Not Yet Recruiting

A Study to Evaluate the Efficacy and Safety of Concomitant Use of Eplontersen and ALXN2220 Compared With Eplontersen and Placebo for Adults Participants With ATTR-CM

for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

24 locations incl. La Jolla

Sponsor: AstraZeneca

Sex: All·Age: 18 - 85

Code: NCT07608354·Phase 2·Not Yet Recruiting

FG001 Near-Infrared Fluorescence Imaging During Tumor Resection in Newly Diagnosed High-Grade Glioma

for High-Grade Glioma (WHO III-IV)

5 locations incl. Miami

Sponsor: FluoGuide A/S

Sex: All·Age: 18+

Code: NCT07609472·Phase 2·Not Yet Recruiting

Impact of Electronic Cigarette Temperature and Solvent on Biomarkers

for Oxidative Stress

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 21+

Code: NCT07612696·Not Yet Recruiting

An International Multicenter, Multivendor Evaluation of the Free-Running Framework for Cardiac Function

for Congenital Heart Diseases

9 locations incl. Los Angeles

Sponsor: Matthias Stuber

Sex: All·Age: All ages

Code: NCT07613398·Not Yet Recruiting

Decision Counseling and Follow-up for Shield+ Patients

for Colo-rectal Cancer

1 location in Philadelphia

Sponsor: Guardant Health, Inc.

Sex: All·Age: 45 - 75·Accepts healthy volunteers

Code: NCT07620535·Not Yet Recruiting

Pilot Deprescribing of Antimuscarinic Overactive Bladder Medications in Parkinson Disease

for Parkinson Disease (PD)

1 location in Philadelphia

Sponsor: Corporal Michael J. Crescenz VA Medical Center

Sex: All·Age: 60+

Code: NCT07627529·Phase 4·Not Yet Recruiting

VorAsidenib With Lomustine In Patients With rEcurrent IDH-mutaNT Glioma Harboring IDH1 and/or IDH2 Mutations

for Brain Cancer

Drug: Vorasidenib

1 location in Pittsburgh

Sponsor: Megan Mantica

Sex: All·Age: 18+

Code: NCT07629089·Phase 1·Not Yet Recruiting

Using Virtual Reality Applications for Younger Patients With Chronic Pain

for Chronic Pain Management

1 location in Allison Park

Sponsor: Elizabeth Pickle

Sex: All·Age: 7 - 21

Code: NCT07630350·Not Yet Recruiting

Bevonescein for Improved Intraoperative Nerve Visualization to Improve Voice Outcomes in Thyroidectomy Patients

for Head and Neck Disorder

1 location in Pittsburgh

Sponsor: Matthew Spector

Sex: All·Age: 18+

Code: NCT07631650·Phase 2·Not Yet Recruiting

AUR103 Calcium in Advanced Neuroendocrine Tumours (BHARAT-3 Study)

for Neuroendocrine (NE) Tumors

5 locations incl. Phoenix

Sponsor: Aurigene Discovery Technologies Limited

Sex: All·Age: 18 - 99

Code: NCT07640737·Phase 2·Not Yet Recruiting

Small Trial of Alendronate Impact on the Reservoir of HIV

for HIV

5 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 65

Code: NCT07216794·Phase 2·Not Yet Recruiting

A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis

for Systemic Sclerosis

Drug: Nerandomilast

30 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07497087·Phase 3·Not Yet Recruiting

A Phase I/II Trial of JR-446 in Mucopolysaccharidosis Type IIIB (MPS IIIB)

for Mucopolysaccharidosis IIIB

3 locations incl. Oakland

Sponsor: JCR Pharmaceuticals Co., Ltd.

Sex: All·Age: Up to 5

Code: NCT07640984·Phase 1, Phase 2·Not Yet Recruiting

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

for Atherosclerosis

11 locations incl. Beverly Hills

Sponsor: Genentech, Inc.

Sex: All·Age: 18 - 80

Code: NCT07448038·Phase 2·Recruiting

Apply to this trial

DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

for Extrapulmonary Neuroendocrine Cancer

Drug: Obrixtamig

21 locations incl. Scottsdale

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07544654·Phase 3·Not Yet Recruiting

A Study to Access Activity and Safety With SAR445399 Compared With Placebo in Participants Aged 18 to 80 Years of Age With Non-Cystic Fibrosis Bronchiectasis

for Non-cystic Fibrosis Bronchiectasis

Drug: SAR445399

3 locations incl. Loxahatchee Groves

Sponsor: Sanofi

Sex: All·Age: 18 - 80

Code: NCT07547436·Phase 2·Recruiting

Apply to this trial

A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection

for HIV-1-infection

10 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT06987318·Phase 1·Not Yet Recruiting

tSCS in Children With Spina Bifida

for Spina Bifida

1 location in Pittsburgh

Sponsor: Bailey Petersen

Sex: All·Age: 4 - 17

Code: NCT07615686·Recruiting

Apply to this trial

A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity

for Obesity

Drug: NNC0662-0419

24 locations incl. Montgomery

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07639021·Phase 2·Not Yet Recruiting

RCT to Assess the Efficacy of Biophoton Therapy to Treat Type 2 Diabetes

for Type 2 Diabetes

2 locations incl. Tampa

Sponsor: First Institute of All Medicines

Sex: All·Age: 18 - 70

Code: NCT07124208·Not Yet Recruiting

Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease

for Sickle Cell Disease

Drug: Ruxolitinib

4 locations incl. Aurora

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: 12 - 45

Code: NCT07252050·Phase 1, Phase 2·Recruiting

Apply to this trial

Colorectal Cancer Screening Preventive Reminder Ordering AssistanCe Via Texting for Improved Visit Encounters

for Behavior, Health

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07636174·Not Yet Recruiting

Preventive Reminder Ordering AssistanCe Via Texting for Improved Visit Encounters

for Behavior, Health

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07636187·Not Yet Recruiting

Health-E You Efficacy Trial for Male Adolescents

for Sexually Transmitted Diseases

8 locations incl. Oakland

Sponsor: Johns Hopkins University

Sex: Male·Age: 13 - 21·Accepts healthy volunteers

Code: NCT06525064·Recruiting

Apply to this trial

Evaluation of the Efficacy, Safety, and Tolerability of LevoCept

for Contraception

27 locations incl. Berkeley

Sponsor: Sebela Women's Health Inc.

Sex: Female·Age: Up to 45·Accepts healthy volunteers

Code: NCT04457076·Phase 3·Not Yet Recruiting

Interpersonal Communication Training and Vaccination Workflow Training Alone and in Combination to Improve Communication and Recommendations About HPV Vaccination in Pharmacies, IMPACT HPV Trial

for Human Papillomavirus-Related Carcinoma

2 locations incl. University Park

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06926062·Not Yet Recruiting

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

for Left Ventricular Systolic Dysfunction

Drug: Finerenone

22 locations incl. Aurora

Sponsor: Bayer

Sex: All·Age: Up to 18

Code: NCT07192952·Phase 3·Recruiting

Apply to this trial

Autologous Fat Grafting Beneath Penile Split Thickness Skin Graft Placement During Penile Reconstruction

for Penis/Surgery

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Male·Age: 18+

Code: NCT07316491·Not Yet Recruiting

Do Video Recordings of Multidisciplinary Clinics Improve Quality of Life for People With ALS and Their Caregivers?

for Amyotrophic Lateral Sclerosis (ALS)

7 locations incl. Scottsdale

Sponsor: Trustees of Dartmouth College

Sex: All·Age: 18+

Code: NCT07454733·Not Yet Recruiting

Pilot and Feasibility Study of Intra-articular Anti-CD14 for the Treatment of Knee Osteoarthritis

for Knee Osteoarthritis (Knee OA)

1 location in Philadelphia

Sponsor: VA Office of Research and Development

Sex: All·Age: 50 - 80

Code: NCT07481474·Phase 1·Not Yet Recruiting

A Phase 2 Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma

for Severe Asthma

Drug: Frevecitinib

15 locations incl. Lancaster

Sponsor: Kinaset Therapeutics Inc

Sex: All·Age: 18 - 75

Code: NCT07532265·Phase 2·Not Yet Recruiting

Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies

for Acute Lymphocytic Leukemia (ALL)

1 location in Pittsburgh

Sponsor: Sawa Ito, MD

Sex: All·Age: 18+

Code: NCT07565220·Phase 1·Not Yet Recruiting

First-in-human Study of a New Treatment (4A10) for Patients With Relapsed or Hard-to-treat Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma, Focused on Safety and How the Drug Behaves in the Body and Early Signs of Effect.

for Lymphoblastic Lymphoma

4 locations incl. Aurora

Sponsor: Allterum Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT07586618·Phase 1·Recruiting

Apply to this trial

Combined Functional Electrical and Transcranial Direct Current Stimulation for Foot Drop

for Falls

1 location in Philadelphia

Sponsor: Saint Joseph's University, Philadelphia

Sex: All·Age: 18+

Code: NCT07592221·Recruiting

Apply to this trial

Imaging CRF X NOP Interactions in Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Pittsburgh

Sponsor: Rajesh Narendran

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07612631·EARLY_Phase 1·Recruiting

Apply to this trial

nVNS, CBD, and SoC for Persistent Post-Traumatic Headache

for Persistent Post Traumatic Headache

8 locations incl. Scottsdale

Sponsor: American Society of Pain and Neuroscience, Inc.

Sex: All·Age: 18 - 75

Code: NCT07624279·Phase 2·Not Yet Recruiting

Retreatment With CTL019/CTL119

for Lymphoma, B-Cell

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT04419909·Phase 1·Not Yet Recruiting

Precision Analgesia for Cardiac Surgery

for Analgesia

1 location in Pittsburgh

Sponsor: Kathirvel Subramaniam

Sex: All·Age: 60 - 110

Code: NCT05612399·Not Yet Recruiting