Precision Analgesia for Cardiac Surgery

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
Kathirvel Subramaniam
Study ID
NCT05612399
Status
Not Yet Recruiting

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Conditions

  • Analgesia
  • Cardiac Surgery

Eligibility Criteria

Sex
ALL
Age
60 Years - 110 Years
Healthy Volunteers
Not accepted

Study Details

The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research. This research focuses on two of the most commonly used oral opioid analgesics, oxycodone, and methadone in elderly adults undergoing cardiac surgery.

Key Dates

Start date
May 31, 2026
Status verified
Apr 2025
Primary completion
Dec 1, 2026
Completion
Dec 1, 2026

Study Design

Enrollment
400 participants (estimated)

Primary Outcome Measure

Determine Genetic Factors - Opioid Related Adverse Events (RD) [ Time Frame: Immediately post-surgery during hospital stay ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UPMC Presbyterian HospitalPittsburghPennsylvania15213
Kathirvel Subramaniam, MD, MPH
[email protected]
Amy Monroe, MPH, MBA
[email protected]
412-623-6382

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By research site
UPMC Presbyterian Hospital· Pittsburgh, PA

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