Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,656 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,656 clinical trials

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Testing the Use of VA Peer Specialists to Prevent Veteran Suicide

for Suicide Risk

3 locations incl. Baltimore

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07286383·Phase 3·Not Yet Recruiting

Effect of cTBS on Startle and TMS-evoked BOLD

for Anxiety

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07415772·Not Yet Recruiting

Validation of NAD+ Measurements for Human Clinical Studies

for Healthy Adults

2 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 110·Accepts healthy volunteers

Code: NCT07416786·Not Yet Recruiting

Efficacy of Integrating Next Generation Sequencing for Treatment of Surgical Site Infection After Fracture Fixation:

for Next Generation Sequencing (NGS)

18 locations incl. Tuscaloosa

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18 - 84

Code: NCT07458230·Phase 3·Not Yet Recruiting

DaxibotulinumtoxinA for Blepharospasm

for Blepharospasm of Both Eyelids

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07489430·Phase 2·Not Yet Recruiting

Testing an Adaptive Intervention for Peer-Supported Mobile Health for Primary Care Veterans With Psychological Distress

for Psychological Distress

5 locations incl. Palo Alto

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07507747·Not Yet Recruiting

Optimizing Stimulation Parameters for Electroconvulsive Therapy

for Depression - Major Depressive Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages

Code: NCT07561307·Not Yet Recruiting

The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial

for Surgical Wounds

1 location in Danville

Sponsor: Geisinger Clinic

Sex: All·Age: 18+

Code: NCT07583862·Phase 2·Not Yet Recruiting

A Widely Inclusive, Hybrid-Decentralized Pilot Trial Utilizing β-hydroxy-β-methylbutyrate to Lower IGFBP7 Levels in People With ALS

for Amyotrophic Lateral Sclerosis ALS

2 locations incl. Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT07589764·Phase 1·Not Yet Recruiting

mHealth Service Linkage for Young Adults Impacted by the Criminal Legal System

for HIV Prevention

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 29·Accepts healthy volunteers

Code: NCT07599722·Not Yet Recruiting

Assessing the Effects of Hormones on Noninvasive Transcranial Stimulation

for Cortical Excitability

1 location in Pittsburgh

Sponsor: Carnegie Mellon University

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT07635017·Not Yet Recruiting

Nature as Medicine for the Healing Brain: Utilization of a Nature-based Exposure Intervention for Decreasing Concussion Recovery Timeline and Symptom Load

for Concussion (Diagnosis)

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 14 - 35

Code: NCT07642739·Not Yet Recruiting

Prediction and Prevention of Postoperative Mortality and Morbidity

for Dementia

5 locations incl. Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 65+

Code: NCT06042413·Not Yet Recruiting

TRACK-TBI Precision Medicine Part 3 - Option II

for Traumatic Brain Injury

2 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 65

Code: NCT06790095·Phase 2·Enrolling By Invitation

Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 65

Code: NCT06807918·Phase 2, Phase 3·Not Yet Recruiting

An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)

for REM Sleep Behavior Disorder

19 locations incl. Los Angeles

Sponsor: Yale University

Sex: All·Age: 50 - 80

Code: NCT06996652·Phase 2·Not Yet Recruiting

The Effect of SPecialty cAre on Recovery From Cardiac Arrest Trial (the SPARC Trial)

for Cardiac Arrest (CA)

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07002294·Not Yet Recruiting

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

for Lymphoma, Non-Hodgkin

23 locations incl. Duarte

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07101328·Phase 1·Not Yet Recruiting

IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)

for Relapsed/Refractory Primary Central Nervous System Lymphoma

Drug: Rituximab

14 locations incl. Phoenix

Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT07104032·Phase 3·Recruiting

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Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

for Epilepsy

12 locations incl. Phoenix

Sponsor: Epiminder America, Inc.

Sex: All·Age: 18 - 75

Code: NCT07110454·Recruiting

Apply to this trial

Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) Trial

for Burn Injury

1 location in Pittsburgh

Sponsor: Jason Sperry

Sex: All·Age: 18 - 75

Code: NCT07212998·Phase 3·Not Yet Recruiting

Novel Self-charging, Medical-Grade Smart Insoles With AI/ML Edge Computing to Monitor Biometrics.

for No Applicable Condition

1 location in Williamsport

Sponsor: Spectrum Ergonomics and Occupational Health Services

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT07273422·Recruiting

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Investigating Real-Time Immunotherapy Symptoms Study

for Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07280715·Not Yet Recruiting

A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With HR+, HER2- Advanced Breast Cancer

for Advanced Breast Cancer

11 locations incl. Hot Springs

Sponsor: TerSera Therapeutics LLC

Sex: Female·Age: 18 - 55

Code: NCT07310420·Phase 1·Recruiting

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A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications

for Parkinson's Disease

26 locations incl. Phoenix

Sponsor: Bayer

Sex: All·Age: 45 - 75

Code: NCT07330258·Recruiting

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A Study of CDX-622 in Participants With Mild to Moderate Asthma

for Mild to Moderate Asthma

4 locations incl. San Francisco

Sponsor: Celldex Therapeutics

Sex: All·Age: 18+

Code: NCT07330778·Phase 1·Recruiting

Apply to this trial

Topical Cryotherapy and Keloid/Hypertrophic Scars

for Keloid Scars

1 location in Pittsburgh

Sponsor: Sonal Choudhary

Sex: All·Age: 18+

Code: NCT07336368·Phase 3·Recruiting

Apply to this trial

Sleep and Circadian Interventions for College Students at High Risk of Suicide

for Sleep Disturbance

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 25

Code: NCT07346014·Not Yet Recruiting

Study of ALK-001 on the Progression of Stargardt Disease

for Stargardt Disease

4 locations incl. Phoenix

Sponsor: Alkeus Pharmaceuticals, Inc.

Sex: All·Age: 8 - 45

Code: NCT07419334·Phase 3·Recruiting

Apply to this trial

T4/T3 Therapy in Hypothyroidism

for Hypothyroidism Primary

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 70

Code: NCT07424183·Phase 2·Not Yet Recruiting

NeuroCuple to Mitigate Post-Wisdom Teeth Extraction Opioid Risks

for Wisdom Teeth

1 location in Pittsburgh

Sponsor: nCap Medical

Sex: All·Age: 18 - 50

Code: NCT07461506·Not Yet Recruiting

H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC)

for Oral Cavity Squamous Cell Carcinoma

3 locations incl. Atlanta

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07484139·Phase 2·Not Yet Recruiting

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability Evaluation of CTAP101 Extended-release Capsules in Pediatric Participants

for CKD Stage 3

5 locations incl. Kansas City

Sponsor: OPKO Health, Inc.

Sex: All·Age: 1 Month - 17

Code: NCT07494045·Phase 2·Not Yet Recruiting

Nanozymes in Endodontics

for Apical Periodontitis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07518901·Phase 4·Not Yet Recruiting

Impact of Loss Aversion Messaging and Anticipated Regret for Inaction on Exercise Adherence in Older Adults

for Mobility Disability

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 65+

Code: NCT07540052·Not Yet Recruiting

Bilevel Positive Airway Pressure (BPAP) for Severe Asthma

for Pediatric Asthma

3 locations incl. New York

Sponsor: Columbia University

Sex: All·Age: 5 - 17

Code: NCT07582211·Not Yet Recruiting

Safety And Tolerability Of Gamma Glutamylcysteine (GGC) Oral Supplementation In MCI Patients

for Mild Cognitive Impairment (MCI)

1 location in Pittsburgh

Sponsor: Pravat Mandal

Sex: All·Age: 55 - 80

Code: NCT07583251·Phase 1·Recruiting

Apply to this trial

Automated IADL Sensing to Refine Measurement of Older Adult Daily Activity

for Cognitive Ability General

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 75+·Accepts healthy volunteers

Code: NCT07585864·Not Yet Recruiting

Modified Coronally Advanced Tunnel for Mandibular Lingual Root Coverage

for Gingival Recession

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 65

Code: NCT07590960·Not Yet Recruiting

Mobile Health Program for Post-Preeclampsia Hypertension

for Hypertension (HTN)

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 18+

Code: NCT07599579·Not Yet Recruiting