Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,656 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,656 clinical trials

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Evaluating Care Integration Between Pediatric Primary Care Providers and WIC Nutritionists

for Weight Gain Trajectory

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT07494097·Not Yet Recruiting

Intensive Locoregional Chemoimmunotherapy, Intradermal Autologous Alpha-DC1 Vaccines, and Systemic Pembrolizumab for Advanced-Stage Ovarian Cancer

for Ovarian Cancer

1 location in Pittsburgh

Sponsor: Kalinski, Pawel, MD, PhD

Sex: Female·Age: 18+

Code: NCT07634094·Phase 2·Not Yet Recruiting

FIBRONEER-ACT: A Study to Test Whether Nerandomilast Helps People With Fibrosing Interstitial Lung Disease at Risk for Disease Progression

for Interstitial Lung Diseases

Drug: Nerandomilast

18 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07540988·Phase 3·Not Yet Recruiting

The Impact of Yoga on Endometriosis-Related Pain

for Endometriosis

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 45

Code: NCT06559852·Recruiting

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Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

for Recurrent Mantle Cell Lymphoma

Drug: Glofitamab

7 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07003295·Phase 2·Recruiting

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Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

for Locally Advanced Lung Non-Small Cell Carcinoma

Drug: Sotorasib

9 locations incl. Sacramento

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07012031·Phase 1, Phase 2·Recruiting

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A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes

for Diabetes Mellitus, Type 2

21 locations incl. New Haven

Sponsor: Novo Nordisk A/S

Sex: All·Age: 10 - 18

Code: NCT07282613·Phase 3·Not Yet Recruiting

Care Coordination and Passive Mobile Data Monitoring to Improve Mental Health Care

for Severe Mental Illness

2 locations incl. West Los Angeles

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07549178·Not Yet Recruiting

Prescribe to Prevent HIV: A Hybrid Trial Helping Addiction Clinics Prevent HIV & Infections Through Safer Drug Use Support

for People Who Use Opioids/People With Opioid Use Disorder (OUD)

4 locations incl. Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07073924·Not Yet Recruiting

Lions Hearts: A Community Approach to Multigenerational Cardiovascular Disease Risk

for Cardiovascular (CV) Risk

1 location in State College

Sponsor: Penn State University

Sex: All·Age: 10+·Accepts healthy volunteers

Code: NCT07147387·Not Yet Recruiting

Testing a Mobile Health Application to Improve HIV Prevention and Substance Use Treatment Among Women Involved in the Carceral System

for Substance Abuse

1 location in Philadelphia

Sponsor: Temple University

Sex: Female·Age: 18+

Code: NCT07432555·Not Yet Recruiting

SnapChole: An International, Time-Bound Prospective Platform Study of Management Strategies and Outcomes in Acute Calculous Cholecystitis

for Cholecystitis, Acute

1 location in Philadelphia

Sponsor: European Society for Trauma and Emergency Surgery

Sex: All·Age: 18+

Code: NCT07568080·Not Yet Recruiting

Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate Cancer

for Prostate Carcinoma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Male·Age: 18+

Code: NCT06024772·Phase 3·Not Yet Recruiting

Real-time Engagement for Learning to Effectively Control Type 2 Diabetes

for Diabetes Mellitus, Type 2

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 16 - 24

Code: NCT06375460·Not Yet Recruiting

Improving the Quality of Care for Asthma Patients at Risk of Exacerbations

for Asthma

6 locations incl. New Haven

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 75

Code: NCT06596512·Not Yet Recruiting

Study to Evaluate the Use of Triheptanoin in Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)

for Medium-chain Acyl-CoA Dehydrogenase Deficiency

1 location in Pittsburgh

Sponsor: Jerry Vockley, MD, PhD

Sex: All·Age: 4+

Code: NCT07097311·Phase 2·Recruiting

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NANT 2021-02: Randomized MIBG With Vorinostat/Dinutuximab/Vorinostat + Dinutuximab

for Neuroblastoma

Drug: Vorinostat

13 locations incl. Los Angeles

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 1 - 30

Code: NCT07261241·Phase 2·Not Yet Recruiting

Psilocybin After Trauma Surgery for Pain

for Pain Management

1 location in Pittsburgh

Sponsor: Trent Emerick

Sex: All·Age: 25 - 65

Code: NCT07406828·Phase 1·Not Yet Recruiting

CD45BE-HSPC + CART-45 Cells

for B-Cell Non-Hodgkin Lymphoma (NHL)

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07451054·Phase 1·Recruiting

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Creation of a Decision Aid for Coronary Anomalies

for AAOCA

5 locations incl. Boston

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 10 - 35

Code: NCT07544979·Not Yet Recruiting

Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion

for Mild Autonomous Cortisol Secretion (MACS)

Drug: Tirzepatide

1 location in Pittsburgh

Sponsor: Alaa Sada

Sex: All·Age: 18+

Code: NCT07573163·Phase 2·Not Yet Recruiting

TCR1188-ABC Cells in KRAS-mutated Cancers

for Cholangiocarcinoma

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07594067·Phase 1·Not Yet Recruiting

Tiprelestat Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH)

for Pulmonary Arterial Hypertension (PAH)

10 locations incl. Tucson

Sponsor: Stanford University

Sex: All·Age: 18 - 75

Code: NCT07601295·Phase 2·Not Yet Recruiting

Axelopran in Patients With Anti-PD-1 Refractory Metastatic or Locoregionally Unresectable Cutaneous Melanoma

for Unresectable Cutaneous Melanoma

1 location in Pittsburgh

Sponsor: John Kirkwood

Sex: All·Age: 18+

Code: NCT07631325·Phase 1, Phase 2·Not Yet Recruiting

The Effect of Osteopathic Manipulative Techniques on Human Tear Proteins

for No Disease or Condition is Being Directly Studied

1 location in Erie

Sponsor: Lake Erie College of Osteopathic Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07633496·Not Yet Recruiting

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain

for Chronic Pain

Drug: LY4065967

36 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07641504·Phase 2·Not Yet Recruiting

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain

for Osteoarthritis, Knee

Drug: LY4065967

36 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 40+

Code: NCT07641517·Phase 2·Not Yet Recruiting

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

for Major Depression

5 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT07226232·Phase 3·Not Yet Recruiting

Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

for Glioma

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 - 21

Code: NCT05555550·EARLY_Phase 1·Recruiting

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A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)

for Fibrosing Interstitial Lung Disease

Drug: Nerandomilast

7 locations incl. Los Angeles

Sponsor: Boehringer Ingelheim

Sex: All·Age: 2 - 17

Code: NCT07366034·Phase 3·Not Yet Recruiting

A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

for Acute Myeloid Leukemia Post Cytotoxic Therapy

5 locations incl. Minneapolis

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT07012044·Phase 1·Recruiting

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Exercise-based Frailty Intervention in Lung Transplantation (XFIT)

for Frailty

4 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 75

Code: NCT06960421·Not Yet Recruiting

Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy

for HIV -1 Infection

10 locations incl. La Jolla

Sponsor: International Maternal Pediatric Adolescent AIDS Clinical Trials Group

Sex: Female·Age: 18+

Code: NCT07637942·Not Yet Recruiting

Patient Navigation to Improve Surgical Access in Primary Hyperparathyroidism

for Hyperparathyroidism, Primary

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06562881·Recruiting

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Improving Heart Health in Individuals With SCI Using Home-Based Virtual Gaming

for Spinal Cord Injuries (SCI)

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18+

Code: NCT06690372·Recruiting

Apply to this trial

Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease

for Overactive Bladder

3 locations incl. Decatur

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07187466·Phase 4·Not Yet Recruiting

Transition From Acute to Chronic Opioid Use and Chronic Pain

for Opioid Use Disorder

1 location in Pittsburgh

Sponsor: Jacques E. Chelly

Sex: All·Age: 18+

Code: NCT07211399·EARLY_Phase 1·Not Yet Recruiting

Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial to Evaluate the Efficacy and Safety of a GLP-1 Receptor Agonist Semaglutide in U.S. Veterans With Alcohol Use Disorder

for Alcohol Use Disorder

Drug: Semaglutide

1 location in Philadelphia

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07218354·Phase 3·Not Yet Recruiting

Development of an Eating Behavior Risk Score

for Obesity

1 location in State College

Sponsor: Penn State University

Sex: All·Age: 7 - 9·Accepts healthy volunteers

Code: NCT07266506·Not Yet Recruiting

COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"

for New Onset Refractory Status Epilepticus

Drug: Tocilizumab

25 locations incl. Phoenix

Sponsor: Yale University

Sex: All·Age: 2+

Code: NCT07281027·Phase 3·Not Yet Recruiting