The Effect of SPecialty cAre on Recovery From Cardiac Arrest Trial (the SPARC Trial)

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
University of Pittsburgh
Study ID
NCT07002294
Status
Not Yet Recruiting

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Conditions

  • Cardiac Arrest (CA)
  • Heart Arrest
  • Heart Arrest, Out-Of-Hospital

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Transfer to specialty care — OTHER
    Interfacility transport and treatment at the specialty care hospital
  • Usual care — OTHER
    Hospitalization and treatment at the closest appropriate facility

Study Details

This randomized clinical trial will determine if adult participants who are in the emergency department after being resuscitated from a cardiac arrest outside of the hospital benefit from care delivered at specialized centers. The main question that it will answer is whether transferring participants to a hospital with a specialized cardiac arrest service improves recovery of function after 90 days. Participants will receive all usual medical care, but some participants will be offered transfer to a regional cardiac arrest center and others will be offered care at the closest appropriate hospital. Investigators will interview participants after 90 days to assess their recovery.

Key Dates

Start date
Jun 30, 2026
Status verified
Jul 2025
Primary completion
Jun 30, 2031
Completion
Jan 31, 2032

Study Design

Enrollment
1,618 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Transfer to specialty care
    Participants randomized to receive specialty care will undergo immediate interfacility transport to and hospital treatment at the specialty care hospital
  • Active Comparator: Usual care
    Participants randomized to the usual care arm will be hospitalized at the first hospital or transferred to the closest appropriate hospital

Primary Outcome Measure

Modified Rankin Scale [ Time Frame: 90 Days post arrest ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Pittsburgh Department of Emergency MedicinePittsburghPennsylvania15213
Sara DiFiore-Sprouse
[email protected]
4128642284
Jonathan Elmer, MD, MS (PRINCIPAL_INVESTIGATOR)
Clifton Callaway, MD, PhD (SUB_INVESTIGATOR)
Francis Guyette, MD, MPH (SUB_INVESTIGATOR)

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By research site
University of Pittsburgh Department of Emergency Medicine· Pittsburgh, PA

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