As of June 2026, 42 paid clinical trials are recruiting for Heart failure in Boston, Massachusetts. Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Boston has approximately 3,013 recruiting research studies across a wide range of therapeutic areas. Massachusetts is a global epicenter of biomedical research, anchored by Harvard-affiliated hospitals (MGH, Brigham and Women's, Dana-Farber), Boston Children's Hospital, and the Kendall Square biotech corridor in Cambridge.
Researchers run research studies in Boston, MA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Massachusetts General Hospital | Breast Cancer, Advanced Solid Tumor, Colorectal Cancer | 710 |
| Brigham and Women's Hospital | Prostate Cancer, Breast Cancer, Obesity | 365 |
| Dana-Farber Cancer Institute | Breast Cancer, Acute Myeloid Leukemia, Multiple Myeloma | 349 |
| Beth Israel Deaconess Medical Center | Breast Cancer, Multiple Myeloma, Acute Myeloid Leukemia | 281 |
| Boston Children's Hospital | Congenital Heart Disease, Cystic Fibrosis, Sickle Cell Disease | 266 |
| Dana Farber Cancer Institute | Breast Cancer, Ovarian Cancer, Prostate Cancer | 235 |
| Tufts Medical Center | Heart Failure, Breast Cancer, Acute Myeloid Leukemia | 123 |
| Boston Medical Center | Amblyopia, Atrial Fibrillation, Sickle Cell Disease | 106 |
| Massachusetts General Hospital Cancer Center | Breast Cancer, Coping Skills, Glioma | 64 |
| VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA | Chronic Obstructive Pulmonary Disease, Mild Traumatic Brain Injury, Opioid Use Disorder | 29 |
| Boston University | Gulf War Illness, Gulf War Syndrome, Obsessive-Compulsive Disorder | 28 |
| Brigham & Women's Hospital | Attention, Chronic Lymphocytic Leukemia, Critical Illness | 28 |
| Joslin Diabetes Center | Type 1 Diabetes Mellitus, Diabetes Mellitus, Type 1, T1D | 22 |
| Mass General Brigham | Heart Failure, Heart Failure With Preserved Ejection Fraction, Advanced Solid Tumors | 22 |
| Northeastern University | Cognitive Change, Healthy, Adults Without Language Disorder | 20 |
| Massachusetts Eye and Ear | Cone Rod Dystrophy, Glaucoma, Juvenile Macular Degeneration | 17 |
| Clinical Trial Site | Transthyretin Amyloidosis With Cardiomyopathy, ATTR Amyloidosis, Acid Cholesteryl Ester Hydrolase Deficiency, Type 2 | 15 |
| Brigham and Womens Hospital | Asthma, Advanced Prostate Cancer, Alpha1-Antitrypsin Deficiency | 13 |
| Massachusetts Eye and Ear Infirmary | Laryngeal Dystonia, Stargardt Disease, Age-related Macular Degeneration | 12 |
| Ophthalmic Consultants of Boston | Macular Edema Secondary to Inflammation, Neovascular Age-related Macular Degeneration, AMD | 12 |
| Adams Clinical Boston | Major Depressive Disorder, Alcohol Use Disorder, Alzheimers Disease | 11 |
| Beth Israel Deaconess Medical Center (BIDMC) | Ovarian Cancer, Prostate Cancer, Advanced Melanoma | 11 |
| Boston Childrens Hospital | CSTB-related Disease, Crohn's Disease, Cystic Fibrosis | 11 |
| Mass General Hospital | ALL, Adult, AML, Acute Lower Limb Arterial Occlusion | 10 |
| Boston Clinical Trials | Focal Epilepsy, Chronic Low-back Pain, Depressive Disorder, Major | 9 |
Recruiting trials in Boston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in Massachusetts are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Massachusetts trials follow additional state privacy requirements enforced under 201 CMR 17.00 and oversight from the Massachusetts Department of Public Health.
Hipa.ai aggregates every recruiting study in Boston from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 3,013 recruiting clinical trials in Boston, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Boston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Boston include Breast Cancer (64), Prostate Cancer (43), Heart Failure (36), Ovarian Cancer (36), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Boston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Boston include Massachusetts General Hospital, Brigham and Women's Hospital, Dana-Farber Cancer Institute, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Boston are Cancer & tumors (932), Neurology & pain (228), Cardiovascular (187). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.