Increasing CRC Screening in Community Health Centers Through Mobile Messaging Optimization

Conditions

• Colorectal Cancer

Eligibility Criteria

Sex

ALL

Age

45 Years - 75 Years

Healthy Volunteers

Accepted

Interventions

• Personalized Text Message — BEHAVIORAL
  Message includes personalized content.
• Screening Concerns Text Message — BEHAVIORAL
  Emotional concerns or barriers related to CRC screening.
• Message Framing Text Message — BEHAVIORAL
  Use gain-framed language to influence motivation.
• Autonomy Support Outreach — BEHAVIORAL
  Provide patients with choices or options to increase sense of control.
• Impediments Support Outreach — BEHAVIORAL
  Include information or resources to help overcome barriers to care.
• Live Support Outreach — BEHAVIORAL
  Offer access to live assistance.
• Data Reporting and Visualization System Tools — OTHER
  Electronic alerts, dashboards, and tracking systems used to identify and follow up with patients due for CRC screening or abnormal results.

Study Details

The goal of this interventional study is to create and test a comprehensive and low burden text message program within existing Community Health Centers (CHC) electronic records system to encourage patients to complete at home colorectal cancer (CRC) screening and to make sure they get follow-up care if their results are abnormal. First, the investigators will learn from clinic staff and patients what their needs and preferences are in terms of use of technology. This information will be used to design the text messages program. * Clinic patients will participate in focus groups * Clinic staff will participate in interviews Second, the investigators will test a series of different message versions in two batches (experiments): * Clinic patients with orders for an at-home colorectal cancer screening kit will receive the different message versions. * In the first batch, the messages that get the most engagement from patients will be selected to be used in the second experiment. * In the second batch, the investigators will test which messages lead to the most colorectal cancer screening completion. * This will be rolled-out within the clinics existing electronic record system. The study team will not receive any information that will identify individual patients. Lastly, the investigators will check again with clinic staff to learn how the program performed, and what would be needed to continue using the text message program in the long run. -Clinic staff will participate in interviews and surveys.

Key Dates

Start date

Dec 31, 2026

Status verified

Jun 2026

Primary completion

Oct 31, 2031

Completion

Jan 31, 2032

Study Design

Enrollment

7,220 participants (estimated)

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

HEALTH_SERVICES_RESEARCH

Arms

• Experimental: Standard Message - Gain Frame
  No personalization, no concerns/negative emotion, gain-framed message.
• Experimental: Concern Message - Gain Frame
  No personalization, screening concerns/negative emotions, gain-framed message.
• Experimental: Concern Message - No Gain Frame
  No personalization, screening concerns/negative emotions, no gain-framed message.
• Experimental: Standard Message - No Gain Frame
  No personalization, no screening concerns/negative emotions, no gain-framed message.
• Experimental: Personalized Message - Gain Frame
  Personalization included, no screening concerns/negative emotions, gain-framed message.
• Experimental: Personalized Message - No Gain Frame
  Personalization included, no screening concerns/negative emotions, no gain-framed message.
• Experimental: Personalized - Concern Message - Gain Frame
  Personalization and screening concerns/negative emotions, gain framed message.
• Experimental: Personalized - Concern Message - No Gain Frame
  Personalization and screening concerns/negative emotions, no gain-framed message.
• Experimental: Basic Outreach Only
  No autonomy support, no impediments support, no live support.
• Experimental: Outreach + Impediments Support
  No autonomy support, no live support. Impediment support.
• Experimental: Outreach + Impediments + Live Support
  No autonomy support. Impediment support and live support included.
• Experimental: Outreach + Live Support
  Live support included. No autonomy or impediments support.
• Experimental: Autonomy Outreach Support
  Autonomy support included, no impediments or live support.
• Experimental: Autonomy + Live Support
  Autonomy and live support with impediments support.
• Experimental: Autonomy + Impediments Support
  Autonomy and impediments support included. No live support included.
• Experimental: Autonomy + Impediments + Live Support
  Autonomy, impediments, and live support included.

Primary Outcome Measure

Text message engagement [ Time Frame: 14 days after reminder message delivery ]

Central Contacts

• Yamila Sierra
  303-724-4811
  [email protected]

Locations (4)

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