Paid Clinical Trials in Illinois

Illinois has 2,953 paid clinical trials enrolling now across cities including Chicago, Peoria and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,953 clinical trials

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Towards Causal Mapping of Episodic Memory iEEG Networks Via Multi-method Brain Stimulation

for Memory Performance

3 locations incl. Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT07378332·Enrolling By Invitation

Intracranial EEG to Test How Noninvasive Stimulation Affects Hippocampal-dependent Memory

for Memory Performance

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT07397897·Enrolling By Invitation

A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases

for Interstitial Lung Diseases

Drug: Nerandomilast

33 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06806592·Phase 3·Recruiting

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Ischemic Preconditioning in Osteoarthritis and Back Pain

for Low Back Pain

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 50+

Code: NCT07003113·Recruiting

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Stable Isotopes- Adults With Obesity

for Obese Patients (BMI ≥ 30 kg/m²)

1 location in Urbana

Sponsor: University of Illinois at Urbana-Champaign

Sex: All·Age: 19 - 59·Accepts healthy volunteers

Code: NCT07020741·Recruiting

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A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO

for Neovascular Age-Related Macular Degeneration (NVAMD)

49 locations incl. Scottsdale

Sponsor: EyeBiotech Ltd.

Sex: All·Age: 18+

Code: NCT07205887·Phase 2·Recruiting

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A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

for Breast Neoplasms

46 locations incl. Hot Springs

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06926868·Phase 2, Phase 3·Recruiting

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Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema

for Pleural Infection Bacterial

6 locations incl. New Haven

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+

Code: NCT07095361·Phase 4·Recruiting

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Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

for Atrial Fibrillation (AF)

18 locations incl. Birmingham

Sponsor: Arga Medtech SA

Sex: All·Age: 18 - 80

Code: NCT06784466·Recruiting

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A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer

for Non-Muscle Invasive Bladder Neoplasms

22 locations incl. Sun City

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06919965·Phase 3·Recruiting

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Community-based Approach to Lowering Stress Through Mindfulness

for Depression

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06987799·Recruiting

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Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer

for Gastric Cancer

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT04107077·Phase 2·Recruiting

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Comparing Antibiotic Treatment Strategies for Children With Pneumonia in Outpatient Settings: (STAMPP)

for Community Acquired Pneumonia (CAP)

4 locations incl. Atlanta

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 12 Months - 71 Months

Code: NCT06986148·Recruiting

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Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)

for Kidney Disease

3 locations incl. Victorville

Sponsor: Bodyport Inc.

Sex: All·Age: 21+

Code: NCT07059962·Recruiting

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Hypofractionation (Radiation) Trial for Multiple Myeloma

for Multiple Myeloma

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT06270888·Phase 1·Recruiting

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Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

for Metastatic Clear Cell Renal Cell Carcinoma

Drug: Cabozantinib

40 locations incl. Gilbert

Sponsor: Arcus Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07011719·Phase 3·Recruiting

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Education & Mentorship of Advanced Practice Providers to Increase Community-based Research Within the NCORP Network, COACH-APP Trial

for Other

31 locations incl. Newark

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06904391·Recruiting

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A Study to Evaluate the Safety and Efficacy of BGB-16673 Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

36 locations incl. Phoenix

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06973187·Phase 3·Recruiting

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Emotion, Aging, and Decision Making

for Motivation

1 location in Chicago

Sponsor: DePaul University

Sex: All·Age: 65 - 80·Accepts healthy volunteers

Code: NCT06071130·Not Yet Recruiting

A Study to Evaluate the Dose Levels, Safety, and Drug Levels of Single KarXT Intramuscular Injection in Participants With Schizophrenia

for Schizophrenia

Drug: KarXT

8 locations incl. Los Alamitos

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 55

Code: NCT07061288·Phase 1·Recruiting

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Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

for Viral Pneumonia

22 locations incl. Sacramento

Sponsor: Synairgen Research Ltd.

Sex: All·Age: 18+

Code: NCT06999603·Phase 2·Recruiting

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Fight Fatigue: A Progressive Muscle Relaxation and Walking Intervention to Reduce Fatigue in Adults With ESKD

for End Stage Renal Disease on Dialysis

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT07014111·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

for Colorectal Cancer

22 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07023289·Phase 2·Recruiting

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OPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual Acuity

for Vision Loss Night

23 locations incl. Chandler

Sponsor: Ocuphire Pharma, Inc.

Sex: All·Age: 18+

Code: NCT07140783·Phase 3·Recruiting

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Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

for Elevated Lp(a)

Drug: Muvalaplin

121 locations incl. Gilbert

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07157774·Phase 3·Recruiting

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Parent-Educator Action Response

for Attention Deficit and Disruptive Behavior Disorders

1 location in Chicago

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: All ages

Code: NCT07203014·Enrolling By Invitation

Spinal Stimulation and Gait Training to Improve Mobility in TBI

for Traumatic Brain Injury

2 locations incl. Chicago

Sponsor: Kessler Foundation

Sex: All·Age: 18 - 65

Code: NCT06886152·Not Yet Recruiting

Pupillometry in Delayed Sleep Wake Phase Disorder

for Delayed Sleep-Wake Phase Disorder

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 16+

Code: NCT06949644·Recruiting

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Investigating Patient Satisfaction With Smart Knee Implants

for Total Knee Arthroplasty

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06968143·Recruiting

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A Study to Investigate the Effect of a Multivitamin, Multi-nutrient Supplement on Mental and Emotional Wellbeing

for Menopause

1 location in Chicago

Sponsor: Biologica Inc

Sex: Female·Age: 43 - 55·Accepts healthy volunteers

Code: NCT07146321·Not Yet Recruiting

Fall Prevention Among People With Spinal Cord Injury and Multiple Sclerosis Who Use Wheelchairs and Scooters

for Spinal Cord Injuries (SCI)

1 location in Urbana

Sponsor: University of Illinois at Urbana-Champaign

Sex: All·Age: 18+

Code: NCT07167680·Recruiting

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Emotional Well-being and Measures of Healthy Aging

for Aging

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 40 - 70·Accepts healthy volunteers

Code: NCT07334106·Recruiting

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PDT vs Peels for Treatment of Actinic Keratoses

for Actinic Keratoses

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04429308·Phase 2·Not Yet Recruiting

Pre-emptive Anakinra for Cytokine Event Reduction

for B-Acute Lymphoblastic Leukemia

1 location in Chicago

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 1 - 25

Code: NCT06703216·Phase 1, Phase 2·Not Yet Recruiting

Laterality Training and Pain Drawings

for Chronic Musculoskeletal Pain

2 locations incl. Moline

Sponsor: Hawaii Pacific University

Sex: All·Age: 18+

Code: NCT07078084·Not Yet Recruiting

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

for Schizophrenia

22 locations incl. Bryant

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18+

Code: NCT07105111·Phase 4·Recruiting

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Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

for Neurofibromatosis 1

Drug: Selumetinib

15 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 1 - 8

Code: NCT06188741·Phase 2·Recruiting

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Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection

for Liver Transplant Surgery

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06698146·Recruiting

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A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

for Metastatic Gastric Adenocarcinoma

19 locations incl. Chandler

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07043400·Phase 3·Recruiting

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A Study to Evaluate KYN-5356 in Adults With Cognitive Impairment Associated With Schizophrenia

for Cognitive Impairment Associated With Schizophrenia (CIAS)

13 locations incl. Little Rock

Sponsor: Kynexis B.V.

Sex: All·Age: 18 - 55

Code: NCT07191483·Phase 2·Recruiting

Apply to this trial