Ischemic Preconditioning in Osteoarthritis and Back Pain

Part of paid clinical trials in Chicago, Illinois.

Sponsor
University of Illinois at Chicago
Study ID
NCT07003113
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Ischemic Preconditioning — DEVICE
    The intervention arm will include full blood flow occlusion in one thigh for 5 minutes followed by 5 minutes of reperfusion for a cycle of 50 minutes.
  • Sham Intervention — DEVICE
    This intervention includes 25mmHg of pressure, which is not sufficient for blodo flow occlusion.

Study Details

We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in individuals with knee osteoarthritis and low back pain.

Key Dates

Start date
Sep 12, 2025
Status verified
Jun 2025
Primary completion
Jul 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
24 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: IC Arm
  • Sham Comparator: Sham Arm

Primary Outcome Measure

Preferred walking speed [ Time Frame: At baseline (from enrollment) until end of intervention (3 weeks). ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Human and Sport Performance LabChicagoIllinois60608
Shraddha Sudhir
[email protected]
312-413-5118

Find similar trials in Chicago, IL

By condition
Osteoarthritis (other)
By specialty
OrthopedicsMusculoskeletal disorders
By research site
Human and Sport Performance Lab· Chicago, IL

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