Clinical Trials at Medical University of South Carolina

As of June 2026, 407 paid clinical trials are recruiting at Medical University of South Carolina, located at 96 JONATHAN LUCAS ST, SUITE 309, CHARLESTON, SC 29425-8900, phone (843) 792-3221 in Charleston, South Carolina. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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407 clinical trials at Medical University of South Carolina

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The REPOSE (Reach for Equity in Pediatric Sleep Evaluation) Navigation Intervention

for Sleep Apnea, Obstructive

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 2 - 12

Code: NCT06828835·Recruiting

Apply to this trial

GLP1 Fasting Status and Gastric Retention Using Gastric Ultrasound

for Gastric Retention

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07251803·Recruiting

Apply to this trial

A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

11 locations incl. Birmingham

Sponsor: Rein Therapeutics

Sex: All·Age: 40+

Code: NCT06968845·Phase 2·Recruiting

Apply to this trial

Behavioral Health Collaborative Care Model in an ICU Recovery Clinic

for PICS

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07372586·Recruiting

Apply to this trial

Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot

for Critical Illness Recovery

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07390786·Recruiting

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Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)

for Hepatitis

Drug: Larsucosterol

48 locations incl. Birmingham

Sponsor: Bausch Health Americas, Inc.

Sex: All·Age: 18+

Code: NCT07428538·Phase 3·Recruiting

Apply to this trial

Feasibility of a Technology-Based Intervention for Depression Referral Uptake in Cancer Survivors

for Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07091968·Recruiting

Apply to this trial

Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)

for Heart Failure

4 locations incl. Los Angeles

Sponsor: Echosens

Sex: All·Age: 18+

Code: NCT07222813·Not Yet Recruiting

SUPPORT-T in Patients With Progressive Pulmonary Fibrosis and Their Caregivers

for Progressive Pulmonary Fibrosis

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07269262·Recruiting

Apply to this trial

Methadone in THA for Post-op Pain and Opioid Reduction

for Post Operative Pain

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 75

Code: NCT07227064·Phase 3·Recruiting

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Methadone in TKA for Post-op Pain and Opioid Reduction

for Post Operative Pain

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 75

Code: NCT07226076·Phase 3·Recruiting

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Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

15 locations incl. Little Rock

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting

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A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis

for Atopic Dermatitis

Drug: Tapinarof

37 locations incl. Birmingham

Sponsor: Organon and Co

Sex: All·Age: 3 Months - 23 Months

Code: NCT07265479·Phase 3·Recruiting

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A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

for Breast Neoplasms

117 locations incl. Anchorage

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07174336·Phase 3·Recruiting

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Autophagy Maintenance (AUTOMAIN)

for Ovarian Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06971744·Phase 2·Recruiting

Apply to this trial

A Long-term Follow-up Study in Patients Who Received BEAM-101

for Hemoglobinopathy

17 locations incl. Birmingham

Sponsor: Beam Therapeutics Inc.

Sex: All·Age: 14 - 37

Code: NCT07373639·Recruiting

Apply to this trial

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

for Miscellaneous Neoplasm, Nos

231 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07091617·Recruiting

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A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis

for Plaque Psoriasis

Drug: Zasocitinib

11 locations incl. Chula Vista

Sponsor: Takeda

Sex: All·Age: 4 - 17

Code: NCT07250802·Phase 3·Recruiting

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Evaluating the Communication Between Patients and Providers in Cancer Clinics

for Cancer

3 locations incl. Chicago

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+

Code: NCT06985953·Recruiting

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Formoterol in Diabetes

for Diabetic Nephropathies

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 75

Code: NCT07022418·Phase 2·Recruiting

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A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)

for Inflammatory Arthritis

6 locations incl. Phoenix

Sponsor: Smith & Nephew, Inc.

Sex: All·Age: 18 - 80

Code: NCT07199738·Not Yet Recruiting

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

for Systemic Lupus Erythematosus (With and Without Nephritis)

12 locations incl. Phoenix

Sponsor: Allogene Therapeutics

Sex: All·Age: 18 - 69

Code: NCT07085104·Phase 1·Recruiting

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A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

for Ovarian Cancer

Drug: INCB123667

42 locations incl. Mobile

Sponsor: Incyte Corporation

Sex: Female·Age: 18 - 99

Code: NCT07023627·Phase 2·Recruiting

Apply to this trial

Remimazolam vs Propofol in Laser Burn Cases

for Burn Scar

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07213544·Phase 4·Recruiting

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A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

for Eosinophilic Esophagitis (EoE)

Drug: Dupilumab

10 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 6 Months - 6

Code: NCT07112378·Phase 3·Recruiting

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sTMS Combined With CIMT and taVNS In Infants With Hemiplegia

for Hemiplegia

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 8 Months - 24 Months

Code: NCT07063446·Recruiting

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Technology-Enhanced Therapy vs. Medication Monitoring for Buprenorphine Retention in Pregnant Persons

for Opioid Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: Female·Age: 18 - 45

Code: NCT06999811·Recruiting

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Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for Locally Advanced Cervical Adenocarcinoma

260 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07061977·Phase 3·Recruiting

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Examining Whether Project Support Works

for Parent-Child Relations

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 6 - 13

Code: NCT06963554·Recruiting

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A Study of Zasocitinib in Adults With Nonsegmental Vitiligo

for Nonsegmental Vitiligo

Drug: Zasocitinib

23 locations incl. Bryant

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT07108283·Phase 2·Recruiting

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Motoneuron Recruitment and Motor Evoked Potential Up-Conditioning (MEP) in Spinal Cord Injury (SCI)

for Spinal Cord Injuries and Disorders (SCI/D)

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07179822·Recruiting

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Closed-loop rTMS-EEG During Visuomotor Integration.

for Visuomotor Skills

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07249801·Recruiting

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SPI-1005 for the Treatment of Meniere's Disease (Open Label)

for Meniere's Disease

9 locations incl. Los Angeles

Sponsor: Sound Pharmaceuticals, Incorporated

Sex: All·Age: 18 - 75

Code: NCT06859788·Phase 3·Recruiting

Apply to this trial

OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

for Cardiac Failure

7 locations incl. Los Angeles

Sponsor: Inova Health Care Services

Sex: All·Age: 18 - 99

Code: NCT06939751·Recruiting

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Outcomes Tracking in Unilateral Vocal Fold Paralysis (UVFP) and Atrophy After Medialization Laryngeal Surgery

for Unilateral Vocal Cord Paralysis

10 locations incl. La Jolla

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT07579364·Enrolling By Invitation

Peripheral Nerve Stimulation With the SPRINT® System in Chronic PSIJC Pain

for Lower Back Pain

2 locations incl. Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07166952·Recruiting

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A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

for Ovarian Neoplasms

82 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213804·Phase 3·Recruiting

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NeoCARD: Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Triple-Negative Breast Cancer Patients

for Triple Negative Breast Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06845319·Phase 2·Recruiting

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Evaluating the Long-term Safety and Tolerability of Imatinib in Patients With Lymphangioleiomyomatosis (LAM)

for Lymphangioleiomyomatosis (LAM)

2 locations incl. New York

Sponsor: Columbia University

Sex: Female·Age: 18 - 64

Code: NCT06889168·Phase 1·Recruiting

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Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for Colorectal Cancer Stage II

376 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07018869·Phase 3·Recruiting

Apply to this trial