Closed-loop rTMS-EEG During Visuomotor Integration.

Part of paid clinical trials in Charleston, South Carolina.

Sponsor
Medical University of South Carolina
Study ID
NCT07249801
Status
Recruiting
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Conditions

  • Brain Lesion (General)
  • Visuomotor Skills

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • repetitive transcranial magnetic stimulation (rTMS) — DEVICE
    rTMS will be applied time-locked to the intrinsic brain rhythms to individually-defined brain regions

Study Details

This pilot study aims at establishing personalized state-based rTMS for precision neurorehabilitation, we designed a within-subject cross-over study to test closed-loop repetitive transcranial magnetic stimulation and electroencephalography (rTMS-EEG) comparing the targeting of two key nodes in the frontoparietal network during bimanual visuomotor force tracking in persons with upper extremity sensorimotor impairment affecting eye-hand control.

Key Dates

Start date
Nov 1, 2025
Status verified
Nov 2025
Primary completion
Aug 31, 2026
Completion
Aug 31, 2027

Study Design

Enrollment
20 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Arms

  • Experimental: state-dependent repetitive transcranial magnetic stimulation (rTMS)
    Repetitive TMS will be applied to cortical targets based on task-based (visuomotor) brain activation.

Primary Outcome Measure

Change of whole hand grip force precision [ Time Frame: 90 minutes ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Medical University of South CarolinaCharlestonSouth Carolina29425-

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Medical University of South Carolina· Charleston, SC