GLP1 Fasting Status and Gastric Retention Using Gastric Ultrasound

Conditions

• Gastric Retention

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Gastric Ultrasound — DIAGNOSTIC_TEST
  All participants will undergo a gastric ultrasound in the preoperative area prior to their scheduled procedure. The patient will be placed in supine position. A curvilinear ultrasound probe will be placed on the sagittal plane below the xiphoid process. The probe will then slide along the costal margin to the right until the gastric antrum is identified. At this point, the ultrasound image will be obtained, and appropriate measurements will be taken. The patient will be placed in the right lateral decubitus position (RLD), and the above procedure will be repeated. The measurement of gastric antral cross-sectional area while in the RLD position will be recorded and used to calculate the gastric volume.

Study Details

This study will enroll patients 18 years and older who are taking a GLP-1/GIP medication and 1) are scheduled for elective surgery and meet ASA fasting guidelines (nothing by mouth for at least 8 hours prior), or 2) scheduled elective colonoscopy and have been on a clear liquid diet for at least 24 hours prior. Participants will have a gastric ultrasound prior to surgery to measure any retained gastric contents. The purpose of this study is to determine if people taking GLP-1 receptor agonists and who fast normally are at an equal risk for having retained gastric contents after appropriately fasting for surgery, compared to patients who are on a liquid only diet for 24 hours prior to surgery.

Key Dates

Start date

Feb 3, 2026

Status verified

Feb 2026

Primary completion

Dec 31, 2026

Completion

Dec 31, 2026

Study Design

Enrollment

150 participants (estimated)

Arms

• Arm: ASA fasting guidelines
  Scheduled elective surgery and meet ASA fasting guidelines (NPO for at least 8 hours prior)
• Arm: 24-hour clear liquid diet
  Scheduled elective colonoscopy and have been on a clear liquid diet for at least 24 hours prior

Primary Outcome Measure

Pre-operative gastric volume per unit of weight (ml/kg) as assessed by gastric ultrasound. [ Time Frame: From enrollment until completion of pre-operative gastric ultrasound (typically within 3 hours of scheduled procedure). ]

Central Contacts

• Haley Nitchie, MHA
  843-792-1869
  [email protected]

Locations (1)

Find similar trials in Charleston, SC