Clinical Trials at Walter Reed National Military Medical Center

As of June 2026, 75 paid clinical trials are recruiting at Walter Reed National Military Medical Center, located at 8901 ROCKVILLE PIKE, BETHESDA, MD 20889-0001, phone (301) 295-4455 in Bethesda, Maryland. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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75 clinical trials at Walter Reed National Military Medical Center

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Confirmatory Clinical Evaluation of Novilase® Laser Therapy for Focal Destruction of Malignant Breast Tumors

for Malignant Neoplasm of Breast

7 locations incl. Duarte

Sponsor: Novian Health Inc.

Sex: Female·Age: 18+

Code: NCT03463954·Recruiting

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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

820 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting

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A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Drug: Nivolumab

390 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 5 - 60

Code: NCT05675410·Phase 3·Recruiting

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Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

for Recurrent Endometrial Carcinoma

Drug: Selumetinib

293 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05554328·Phase 2·Recruiting

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

475 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting

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A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

for High Grade Osteosarcoma

Drug: Cabozantinib

175 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 40

Code: NCT05691478·Phase 2, Phase 3·Recruiting

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Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for Endometrial Carcinoma

403 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05256225·Phase 3·Recruiting

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Pre- and Post-neuromusculoskeletal Injury Risk Evaluation for Return-to-Duty Enhancement

for Musculoskeletal Injuries

2 locations incl. Bethesda

Sponsor: Womack Army Medical Center

Sex: All·Age: 18 - 44·Accepts healthy volunteers

Code: NCT05111925·Recruiting

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Post-Concussion Musculoskeletal Injury Risks

for Musculoskeletal Injury

3 locations incl. Athens

Sponsor: Walter Reed National Military Medical Center

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT05122728·Recruiting

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Vaginal Estradiol vs Oral Beta-3 Agonist for Overactive Bladder Syndrome

for Overactive Bladder Syndrome

1 location in Bethesda

Sponsor: Walter Reed National Military Medical Center

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT05221021·Phase 4·Recruiting

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Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Postoperative Pain After Mastectomy

for Mastectomy

5 locations incl. Los Angeles

Sponsor: University of California, San Diego

Sex: All·Age: 18+

Code: NCT05444361·Enrolling By Invitation

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

746 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting

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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

164 locations incl. Birmingham

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

219 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting

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Open Versus Arthroscopic Stabilization of Shoulder Instability With Subcritical Bone Loss: The OASIS Trial

for Shoulder Dislocation

15 locations incl. Tempe

Sponsor: University of Pittsburgh

Sex: All·Age: 17 - 50

Code: NCT04809064·Recruiting

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The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction

for Thyroid Eye Disease

1 location in Bethesda

Sponsor: Walter Reed National Military Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06275373·Recruiting

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The Effect of Sex Steroid Replacement Therapy in the Hypogonadism and Transgender Active-Duty Population

for Hypogonadism

1 location in Bethesda

Sponsor: Walter Reed National Military Medical Center

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06247267·Recruiting

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

621 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting

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Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

for Advanced Lung Non-Squamous Non-Small Cell Carcinoma

Drug: Bevacizumab

604 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04181060·Phase 3·Recruiting

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A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

for Down Syndrome

Drug: Nivolumab

202 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 - 30

Code: NCT04546399·Phase 2·Recruiting

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A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

539 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

185 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting

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AMI Construction in Lower Extremity Residual Limbs

for Amputation

3 locations incl. Bethesda

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT04063592·Recruiting

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A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for Low Grade Astrocytoma

Drug: Selumetinib

124 locations incl. Aurora

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 - 21

Code: NCT04166409·Phase 3·Recruiting

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

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Standard Injections Versus Reduced Injections for Intravesical onabotulinumtoxinA Treatment of Overactive Bladder

for Overactive Bladder

1 location in Bethesda

Sponsor: Walter Reed National Military Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04020510·Phase 4·Recruiting

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A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception

for Amputation

4 locations incl. Bethesda

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT03882073·Recruiting

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An Evaluation of Two PTSD Assessments in an Active Duty and Military Veteran Sample

for Stress Disorders, Post-Traumatic

3 locations incl. Honolulu

Sponsor: U.S. Army Medical Research and Development Command

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04180930·Recruiting

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Defense and Veterans Center for Integrative Pain Management (DVCIPM) Pain Registry Biobank

for Pain

2 locations incl. San Diego

Sponsor: Defense and Veterans Center for Integrative Pain Management

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT04004286·Recruiting

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Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

73 locations incl. Tucson

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

152 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting

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Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

for Childhood Extracranial Germ Cell Tumor

566 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT03067181·Phase 3·Recruiting

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

245 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting

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SC2i Tissue and Data Repository Protocol

for Critical Illness

4 locations incl. Atlanta

Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT02182180·Recruiting

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Spinal Cord Injury Registry - North American Clinical Trials Network

for Spinal Cord Injury

13 locations incl. Miami

Sponsor: Robert G. Grossman, MD

Sex: All·Age: 18+

Code: NCT00178724·Recruiting

Apply to this trial