Paid Clinical Trials in Maryland

Maryland has 2,891 paid clinical trials enrolling now across cities including Baltimore, Bethesda and Rockville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Maryland include Johns Hopkins Medicine and NIH Clinical Center, running studies across oncology, cardiology, neurology, and more. The most actively recruiting conditions are Breast Cancer, Prostate Cancer, Obesity, Healthy Volunteers — browse the full list or use the filters to match your diagnosis. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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Healthy volunteers only

2,891 clinical trials

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Tracheostomy Robotics and Cutting-edge Health Education for Airway Safety

for Tracheostomy

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06236542·Not Yet Recruiting

Addressing Health Disparities in Normal Pressure Hydrocephalus (NPH) in Maryland

for Normal Pressure Hydrocephalus

2 locations incl. Baltimore

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06426004·Not Yet Recruiting

Fall Prevention in Mild Cognitive Impairment

for Cognitive Impairment

1 location in Baltimore

Sponsor: VA Office of Research and Development

Sex: All·Age: 65+

Code: NCT07507812·Not Yet Recruiting

Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors

for Critical Illness

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 60 - 99

Code: NCT05326633·EARLY_Phase 1·Not Yet Recruiting

A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep

for ADHD

1 location in Baltimore

Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Sex: All·Age: 8 - 18

Code: NCT07061470·Phase 1, Phase 2·Not Yet Recruiting

Decision Support Tool to Integrate PrEP Into Emergency Departments

for HIV

2 locations incl. Washington D.C.

Sponsor: George Washington University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07279129·Phase 1·Not Yet Recruiting

Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer

for Metastatic Colorectal Adenocarcinoma

Drug: Cemiplimab

1 location in Baltimore

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07147231·Phase 1, Phase 2·Recruiting

Apply to this trial

Improving Functioning Among Aging Women Veterans

for Menopause

2 locations incl. Baltimore

Sponsor: VA Office of Research and Development

Sex: Female·Age: 45+

Code: NCT06580470·Not Yet Recruiting

ED Patient's Perceptions and Acceptability Toward a Novel POC HCV Viral Load Testing

for Hepatitis C

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 100

Code: NCT03767231·Not Yet Recruiting

Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.

for Achilles Tendon Repairs/Reconstructions

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07004764·Phase 1·Not Yet Recruiting

A Study to Evaluate the Efficacy and Safety of CBL-514 Injection for Reducing Subcutaneous Fat ( SUPREME-02 )

for Subcutaneous Fat

Drug: CBL-514

11 locations incl. Encinitas

Sponsor: Caliway Biopharmaceuticals Co., Ltd.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07526974·Phase 3·Not Yet Recruiting

Targeting the Hip Abductors to Reduce Falls in Older Veterans Through A Virtual Multimodal Balance Intervention

for Falls

1 location in Baltimore

Sponsor: VA Office of Research and Development

Sex: All·Age: 65+

Code: NCT07109466·Not Yet Recruiting

Facilitation to Increase Tobacco Treatment

for Serious Mental Illness

1 location in Baltimore

Sponsor: VA Office of Research and Development

Sex: All·Age: All ages

Code: NCT07455526·Not Yet Recruiting

Longitudinal Natural History Protocol for PRKN- and PINK1-Linked PD

for PARKINSON DIS

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 18 - 100

Code: NCT07613112·Not Yet Recruiting

To Investigate the Efficacy of Treatment With Oral NA-921 (Bionetide) Versus Placebo in Females With Rett Syndrome

for Rett Syndrome

14 locations incl. Phoenix

Sponsor: Biomed Industries, Inc.

Sex: Female·Age: 5 - 20

Code: NCT06840496·Phase 3·Recruiting

Apply to this trial

Impact of Exogenous Ketones on Sleep Apnea

for Obstructive Sleep Apnea

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 65

Code: NCT06687655·Phase 1, Phase 2·Not Yet Recruiting

Pivotal Study of N-acetyl-L-leucine for CACNA1A

for CACNA1A

3 locations incl. Baltimore

Sponsor: IntraBio Inc

Sex: All·Age: 4+

Code: NCT07221292·Phase 3·Not Yet Recruiting

OER Glibenclamide for Neuropathic Pain in Multiple Sclerosis

for Multiple Sclerosis

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 65

Code: NCT07221799·Phase 1·Not Yet Recruiting

Ceftriaxone Dosage for Non-Critical Community-Acquired Pneumonia

for Community Acquired Pneumonia (CAP)

2 locations incl. Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT07537413·Phase 4·Not Yet Recruiting

Clinical Trial of an IL-23 Inhibitor for Immune Activation in Clinical Trial of an IL-23 Inhibitor for Immune Activation in People With Schizophrenia

for Schizophrenia

1 location in Catonsville

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT07615075·Phase 4·Not Yet Recruiting

Pediatric Electrocutaneous Analgesia for Children Experiencing Neuropathic Pain

for Neuropathic Pain

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 5 - 26

Code: NCT07264920·Not Yet Recruiting

Peer Support for Liver Transplant Recipients With History of ALD

for Alcohol Use Disorder

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07397598·Not Yet Recruiting

A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

for Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC))

Drug: Ipilimumab

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 12+

Code: NCT07430202·Phase 1·Not Yet Recruiting

The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens

for Anxiety

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 9 - 17

Code: NCT02998502·Not Yet Recruiting

Use of N-Acetylcysteine in the Treatment of Repetitive and Self-Injurious Behaviors in Cornelia de Lange Syndrome

for Cornelia de Lange Syndrome

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 13 - 35

Code: NCT04381897·Phase 2·Not Yet Recruiting

Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance

for Cannabis Use

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06351540·Phase 1·Not Yet Recruiting

Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving

for Alcohol Use Disorder (AUD)

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21 - 65

Code: NCT07148843·Phase 2, Phase 3·Not Yet Recruiting

A Wearable Sensor Platform for Remote Monitoring of Individuals on the Frontotemporal Dementia Spectrum

for Frontotemporal Lobar Degeneration (FTLD)

2 locations incl. Lutherville

Sponsor: BioSensics

Sex: All·Age: 40+

Code: NCT07569367·Not Yet Recruiting

Erector Spinae Plane Block Versus Trigger Point Injection for Chronic Thoracic Myofascial Pain

for Back Pain

5 locations incl. Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80

Code: NCT07632820·Phase 4·Recruiting

Apply to this trial

Behavioral Pharmacology of THC and Beta-Myrcene

for Cannabis Use

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT05432284·Phase 1·Not Yet Recruiting

C-CAR168 CAR T Cell Therapy for Refractory Autoimmune Disease

for Lupus Nephritis (LN)

1 location in Rockville

Sponsor: AbelZeta Inc.

Sex: All·Age: 18 - 70

Code: NCT06935474·Phase 1, Phase 2·Not Yet Recruiting

A Study to Evaluate the Efficacy and Safety of CBL-514 Injection for Reducing Subcutaneous Fat

for Subcutaneous Fat

Drug: CBL-514

11 locations incl. Encinitas

Sponsor: Caliway Biopharmaceuticals Co., Ltd.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07140939·Phase 3·Not Yet Recruiting

Combination Therapy for Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Havre de Grace

Sponsor: Johns Hopkins University

Sex: All·Age: 21 - 65

Code: NCT07249554·Phase 2·Not Yet Recruiting

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

for Colorectal Cancer

Drug: Cemiplimab

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT07281768·Phase 2·Not Yet Recruiting

Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE): An Intervention to Support Decision Making for Critically Ill Children

for Decision Making

3 locations incl. San Francisco

Sponsor: Duke University

Sex: All·Age: All ages

Code: NCT07390773·Not Yet Recruiting

Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR Locally Advanced Rectal Cancer

for Rectal Cancer

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT07580339·Phase 2·Not Yet Recruiting

Psilocybin Efficacy With or Without Pimavanserin Pretreatment

for Mood (Psychological Function)

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT07610135·Phase 1, Phase 2·Not Yet Recruiting

Bempedoic Acid Therapy for Polycystic Kidney Disease

for ADPKD (Autosomal Dominant Polycystic Kidney Disease)

Drug: Bempedoic acid

3 locations incl. Baltimore

Sponsor: Kenneth Hallows

Sex: All·Age: 18 - 60

Code: NCT07282821·Phase 2·Not Yet Recruiting

A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)

for Fibrosing Interstitial Lung Disease

Drug: Nerandomilast

7 locations incl. Los Angeles

Sponsor: Boehringer Ingelheim

Sex: All·Age: 2 - 17

Code: NCT07366034·Phase 3·Not Yet Recruiting

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

for Solid Tumors

18 locations incl. San Francisco

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07492680·Phase 2·Not Yet Recruiting

About research studies in Maryland

Maryland has approximately 2,891 recruiting research studies across a wide range of therapeutic areas. Maryland hosts Johns Hopkins Medicine and the NIH Clinical Center in Bethesda, giving participants access to some of the most advanced early-phase research in the country.

Common conditions studied in Maryland

Breast Cancer (46 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
Prostate Cancer (46 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
Obesity (33 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
Healthy Volunteers (29 active studies). Healthy-volunteer studies examine how new drugs behave in the body, helping researchers understand safety and dosing before later-phase trials.
Multiple Myeloma (25 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Cancer (24 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.

Leading research sponsors in Maryland

Johns Hopkins University
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
University of Maryland, Baltimore
AstraZeneca

Local regulations and guidelines

Clinical trials in Maryland are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Maryland research additionally follows state public health department oversight and any applicable state privacy statutes.

Compensation & what to expect

How payment typically works: Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
Healthy volunteers: Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Maryland. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
What's included beyond payment: Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
Travel and time: Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
Asking about compensation: Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.

How to find a clinical trial in Maryland

Hipa.ai aggregates every recruiting study in Maryland from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.

Frequently asked questions

How many paid clinical trials are currently recruiting in Maryland?

There are approximately 2,891 recruiting clinical trials in Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Maryland pay participants?

Most recruiting trials in Maryland compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Maryland?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Maryland?

The most common conditions under active study in Maryland include Breast Cancer (46), Prostate Cancer (46), Obesity (33), Healthy Volunteers (29), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Maryland?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Maryland on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Maryland?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Browse more clinical trials

All cities in Maryland

Baltimore, MD(1,638)Bethesda, MD(931)Rockville, MD(104)Columbia, MD(81)Glen Burnie, MD(70)Silver Spring, MD(70)Towson, MD(51)Annapolis, MD(48)Gaithersburg, MD(39)Hagerstown, MD(39)Chevy Chase, MD(37)Bel Air, MD(34)Frederick, MD(33)Elkton, MD(29)Lutherville, MD(25)Largo, MD(24)Salisbury, MD(23)Westminster, MD(21)College Park, MD(20)Cumberland, MD(20)Bowie, MD(17)Clinton, MD(17)Olney, MD(17)Easton, MD(16)Oxon Hill, MD(15)Hyattsville, MD(14)Lanham, MD(12)Glenn Dale, MD(11)Beltsville, MD(10)Marriottsville, MD(10)White Marsh, MD(10)Brandywine, MD(8)Ft. Washington, MD(8)Hanover, MD(8)Ocean Pines, MD(8)Wheaton, MD(8)Greenbelt, MD(7)Hunt Valley, MD(7)Pikesville, MD(7)Potomac, MD(7)Randallstown, MD(7)Catonsville, MD(6)Germantown, MD(6)Nottingham, MD(6)Aberdeen, MD(5)Ellicott City, MD(5)Kensington, MD(5)Brooklyn, MD(4)Pasadena, MD(4)Havre de Grace, MD(3)Laurel, MD(3)Lutherville-Timonium, MD(3)Owings Mills, MD(3)Denton, MD(2)Elkridge, MD(2)Fort Deterick, MD(2)Gambrills, MD(2)La Plata, MD(2)Leonardtown, MD(2)Mount Airy, MD(2)Takoma Park, MD(2)Timonium, MD(2)Upper Marlboro, MD(2)Arnold, MD(1)Batlimore, MD(1)Belcamp, MD(1)Berlin, MD(1)Berwyn Heights, MD(1)Bethseda, MD(1)Calverton, MD(1)Charlotte Hall, MD(1)Cheverly, MD(1)District Heights, MD(1)Dundalk, MD(1)Glendale, MD(1)Linthicum, MD(1)Linthicum Heights, MD(1)Multiple Locations, MD(1)New Market, MD(1)Odenton, MD(1)Owing Mills, MD(1)Perry Point, MD(1)Prince Frederick, MD(1)Rosedale, MD(1)Stevensville, MD(1)Waldorf, MD(1)White Plains, MD(1)Windsor Mill, MD(1)

Related healthcare resources in Maryland

Behavioral health news in Maryland Latest Maryland clinical trials research report

Trials by condition in Maryland

Breast Cancer· 46 Prostate Cancer· 46 Obesity· 33 Multiple Myeloma· 25 Stroke· 24 Bladder Cancer· 23