Behavioral Pharmacology of THC and Beta-Myrcene

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
Johns Hopkins University
Study ID
NCT05432284
Phase
PHASE1
Status
Not Yet Recruiting

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Conditions

  • Cannabis Use

Eligibility Criteria

Sex
ALL
Age
18 Years - 55 Years
Healthy Volunteers
Accepted

Interventions

  • Placebo — DRUG
    Placebo (ambient air)
  • THC — DRUG
    Pure THC vapor
  • Beta-Myrcene — DRUG
    Pure beta-myrcene vapor

Study Details

This study will evaluate the pharmacokinetics and pharmacodynamics of vaporized b-myrcene and THC administered via inhalation.

Key Dates

Start date
Jul 31, 2026
Status verified
Feb 2026
Primary completion
Nov 30, 2027
Completion
Nov 30, 2027

Study Design

Enrollment
32 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Placebo Comparator: Placebo
    Placebo (ambient air)
  • Experimental: Vaporized high THC alone
    30mg of vaporized pure THC
  • Experimental: Vaporized low THC alone
    15mg of vaporized pure THC
  • Experimental: Vaporized low beta-myrcene
    2mg of vaporized beta-myrcene
  • Experimental: Vaporized high beta-myrcene
    9mg of vaporized beta-myrcene
  • Experimental: Vaporized low THC and low beta-myrcene
    15mg vaporized THC with 2mg vaporized beta-myrcene
  • Experimental: Vaporized low THC and high beta-myrcene
    15mg vaporized THC with 9mg vaporized beta-myrcene
  • Experimental: Vaporized high THC and low beta-myrcene
    30mg vaporized THC with 2mg vaporized beta-myrcene
  • Experimental: Vaporized high THC and high beta-myrcene
    30mg vaporized THC with 9mg vaporized beta-myrcene

Primary Outcome Measure

Self-reported Drug Effect as assessed by the Drug Effect Questionnaire (DEQ) [ Time Frame: 6 hours ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Johns Hopkins School of Medicine Behavioral Pharmacology Research UnitBaltimoreMaryland21224-

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