The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Part of paid clinical trials in Birmingham, Alabama.
- Sponsor
- PedAL BCU, LLC
- Study ID
- NCT04726241
- Phase
- PHASE1/PHASE2
- Status
- Recruiting
Conditions
- Acute Lymphoblastic Leukemia
- Acute Myeloid Leukemia
- Acute Myeloid Leukemia Post Cytotoxic Therapy
- Juvenile Myelomonocytic Leukemia
- Mixed Phenotype Acute Leukemia
- Myelodysplastic Syndrome
- Myelodysplastic Syndrome Post Cytotoxic Therapy
- Myeloid Leukemia Associated With Down Syndrome
Eligibility Criteria
- Sex
- ALL
- Age
- N/A - 22 Years
- Healthy Volunteers
- Not accepted
Interventions
- Biospecimen Collection — PROCEDUREUndergo collection of blood and/or bone marrow samples
Study Details
This study aims to use clinical and biological characteristics of acute leukemias to screen for patient eligibility for available pediatric leukemia sub-trials. Testing bone marrow and blood from patients with leukemia that has come back after treatment or is difficult to treat may provide information about the patient's leukemia that is important when deciding how to best treat it, and may help doctors find better ways to diagnose and treat leukemia in children, adolescents, and young adults.
Key Dates
- Start date
- Apr 18, 2022
- Status verified
- Apr 2026
- Primary completion
- Dec 31, 2030
- Completion
- Dec 31, 2030
Study Design
- Enrollment
- 960 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- SCREENING
Arms
- Experimental: Screening (biospecimen collection)Patients undergo collection of blood and/or bone marrow samples at baseline, end of treatment cycle(s), and at relapse/refractory disease status (if applicable).
Primary Outcome Measure
Proportion of patients with identification of a priori specified genomic and immunophenotypic targets who enroll on a sub-trial [ Time Frame: Up to 5 years ]
Locations (164)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Children's Hospital of Alabama | Birmingham | Alabama | 35233 | Matthew A. Kutny (PRINCIPAL_INVESTIGATOR) |
| USA Health Strada Patient Care Center | Mobile | Alabama | 36604 | Site Public Contact 800-388-8721 Hamayun Imran (PRINCIPAL_INVESTIGATOR) |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | Brenda J. Wittman (PRINCIPAL_INVESTIGATOR) |
| Banner Children's at Desert | Mesa | Arizona | 85202 | Site Public Contact 480-412-3100 Joseph C. Torkildson (PRINCIPAL_INVESTIGATOR) |
| Phoenix Childrens Hospital | Phoenix | Arizona | 85016 | Site Public Contact 602-546-0920 Dana B. Salzberg (PRINCIPAL_INVESTIGATOR) |
| Banner University Medical Center - Tucson | Tucson | Arizona | 85719 | Site Public Contact Monica M. Davini (PRINCIPAL_INVESTIGATOR) |
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202-3591 | Site Public Contact 501-364-7373 Michael W. Bishop (PRINCIPAL_INVESTIGATOR) |
| Kaiser Permanente Downey Medical Center | Downey | California | 90242 | Site Public Contact 626-564-3455 Robert M. Cooper (PRINCIPAL_INVESTIGATOR) |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | Site Public Contact 909-558-4050 Albert Kheradpour (PRINCIPAL_INVESTIGATOR) |
| Miller Children's and Women's Hospital Long Beach | Long Beach | California | 90806 | Site Public Contact 562-933-5600 Jacqueline N. Casillas (PRINCIPAL_INVESTIGATOR) |
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | Site Public Contact 323-361-4110 Jamie L. Stokke (PRINCIPAL_INVESTIGATOR) |
| Valley Children's Hospital | Madera | California | 93636 | Ruetima Titapiwatanakun (PRINCIPAL_INVESTIGATOR) |
| Kaiser Permanente-Oakland | Oakland | California | 94611 | Aarati V. Rao (PRINCIPAL_INVESTIGATOR) |
| UCSF Benioff Children's Hospital Oakland | Oakland | California | 94609 | Jennifer G. Michlitsch (PRINCIPAL_INVESTIGATOR) |
| Children's Hospital of Orange County | Orange | California | 92868 | Elyssa M. Rubin (PRINCIPAL_INVESTIGATOR) |
| Lucile Packard Children's Hospital Stanford University | Palo Alto | California | 94304 | Jay Michael S. Balagtas (PRINCIPAL_INVESTIGATOR) |
| Rady Children's Hospital - San Diego | San Diego | California | 92123 | Site Public Contact 858-966-5934 William D. Roberts (PRINCIPAL_INVESTIGATOR) |
| UCSF Medical Center-Mission Bay | San Francisco | California | 94158 | Elliot Stieglitz (PRINCIPAL_INVESTIGATOR) |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | Kelly E. Faulk (PRINCIPAL_INVESTIGATOR) |
| Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center | Denver | Colorado | 80218 | Florence Choo (PRINCIPAL_INVESTIGATOR) |
| Connecticut Children's Medical Center | Hartford | Connecticut | 06106 | Site Public Contact 860-545-9981 Michael S. Isakoff (PRINCIPAL_INVESTIGATOR) |
| Yale University | New Haven | Connecticut | 06520 | Stephanie A. Massaro (PRINCIPAL_INVESTIGATOR) |
| Alfred I duPont Hospital for Children | Wilmington | Delaware | 19803 | Sridhi Patel (PRINCIPAL_INVESTIGATOR) |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010 | Jeffrey S. Dome (PRINCIPAL_INVESTIGATOR) |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | - |
| Broward Health Medical Center | Fort Lauderdale | Florida | 33316 | Hector M. Rodriguez-Cortes (PRINCIPAL_INVESTIGATOR) |
| Golisano Children's Hospital of Southwest Florida | Fort Myers | Florida | 33908 | Emad K. Salman (PRINCIPAL_INVESTIGATOR) |
| UF Health Cancer Institute - Gainesville | Gainesville | Florida | 32610 | Site Public Contact 352-273-8010 Brian Stover (PRINCIPAL_INVESTIGATOR) |
| Memorial Regional Hospital/Joe DiMaggio Children's Hospital | Hollywood | Florida | 33021 | Iftikhar Hanif (PRINCIPAL_INVESTIGATOR) |
| Nemours Children's Clinic-Jacksonville | Jacksonville | Florida | 32207 | Sridhi Patel (PRINCIPAL_INVESTIGATOR) |
| Nicklaus Children's Hospital | Miami | Florida | 33155 | Site Public Contact 888-624-2778 Maggie E. Fader (PRINCIPAL_INVESTIGATOR) |
| Arnold Palmer Hospital for Children | Orlando | Florida | 32806 | Jaime M. Libes-Bander (PRINCIPAL_INVESTIGATOR) |
| Nemours Children's Hospital | Orlando | Florida | 32827 | Sridhi Patel (PRINCIPAL_INVESTIGATOR) |
| Nemours Children's Clinic - Pensacola | Pensacola | Florida | 32504 | Site Public Contact Jeffrey H. Schwartz (PRINCIPAL_INVESTIGATOR) |
| Sacred Heart Hospital | Pensacola | Florida | 32504 | - |
| Johns Hopkins All Children's Hospital | St. Petersburg | Florida | 33701 | Jennifer L. Mayer (PRINCIPAL_INVESTIGATOR) |
| Saint Joseph's Hospital/Children's Hospital-Tampa | Tampa | Florida | 33607 | Don E. Eslin (PRINCIPAL_INVESTIGATOR) |
| Saint Mary's Medical Center | West Palm Beach | Florida | 33407 | Site Public Contact 561-822-4745 Matthew D. Ramirez (PRINCIPAL_INVESTIGATOR) |
| Children's Healthcare of Atlanta - Arthur M Blank Hospital | Atlanta | Georgia | 30329 | Himalee S. Sabnis (PRINCIPAL_INVESTIGATOR) |
| Memorial Health University Medical Center | Savannah | Georgia | 31404 | Andrew L. Pendleton (PRINCIPAL_INVESTIGATOR) |
| Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | 96826 | Site Public Contact 808-983-6090 Wade T. Kyono (PRINCIPAL_INVESTIGATOR) |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | Martha M. Pacheco (PRINCIPAL_INVESTIGATOR) |
| Lurie Children's Hospital-Chicago | Chicago | Illinois | 60611 | Site Public Contact 773-880-4562 Jenna Rossoff (PRINCIPAL_INVESTIGATOR) |
| University of Chicago Comprehensive Cancer Center | Chicago | Illinois | 60637 | Gabrielle Lapping-Carr (PRINCIPAL_INVESTIGATOR) |
| University of Illinois | Chicago | Illinois | 60612 | Site Public Contact 312-355-3046 Dipti S. Dighe (PRINCIPAL_INVESTIGATOR) |
| Loyola University Medical Center | Maywood | Illinois | 60153 | Site Public Contact 708-226-4357 Eugene Suh (PRINCIPAL_INVESTIGATOR) |
| Advocate Children's Hospital-Oak Lawn | Oak Lawn | Illinois | 60453 | Site Public Contact 847-723-7570 Rebecca E. McFall (PRINCIPAL_INVESTIGATOR) |
| Advocate Children's Hospital-Park Ridge | Park Ridge | Illinois | 60068 | Site Public Contact Rebecca E. McFall (PRINCIPAL_INVESTIGATOR) |
| Saint Jude Midwest Affiliate | Peoria | Illinois | 61637 | Site Public Contact 888-226-4343 Prerna Kumar (PRINCIPAL_INVESTIGATOR) |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | Site Public Contact 217-545-7929 Gregory P. Brandt (PRINCIPAL_INVESTIGATOR) |
| Northwestern Medicine Central DuPage Hospital | Winfield | Illinois | 60190 | Jenna Rossoff (PRINCIPAL_INVESTIGATOR) |
| Ascension Saint Vincent Indianapolis Hospital | Indianapolis | Indiana | 46260 | Bassem I. Razzouk (PRINCIPAL_INVESTIGATOR) |
| Riley Hospital for Children | Indianapolis | Indiana | 46202 | Site Public Contact 800-248-1199 Sandeep Batra (PRINCIPAL_INVESTIGATOR) |
| Blank Children's Hospital | Des Moines | Iowa | 50309 | Samantha L. Mallory (PRINCIPAL_INVESTIGATOR) |
| University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | Site Public Contact 800-237-1225 Andrew P. Groves (PRINCIPAL_INVESTIGATOR) |
| University of Kentucky/Markey Cancer Center | Lexington | Kentucky | 40536 | Site Public Contact 859-257-3379 James T. Badgett (PRINCIPAL_INVESTIGATOR) |
| Norton Children's Hospital | Louisville | Kentucky | 40202 | Michael J. Ferguson (PRINCIPAL_INVESTIGATOR) |
| Children's Hospital New Orleans | New Orleans | Louisiana | 70118 | Site Public Contact 504-894-5377 Maria C. Velez-Yanguas (PRINCIPAL_INVESTIGATOR) |
| Ochsner Medical Center Jefferson | New Orleans | Louisiana | 70121 | Craig Lotterman (PRINCIPAL_INVESTIGATOR) |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | Site Public Contact 207-973-4274 Daniel L. Callaway (PRINCIPAL_INVESTIGATOR) |
| Maine Children's Cancer Program | Scarborough | Maine | 04074 | Sei-Gyung K. Sze (PRINCIPAL_INVESTIGATOR) |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Baltimore | Maryland | 21287 | Stacy L. Cooper (PRINCIPAL_INVESTIGATOR) |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | Site Public Contact 410-601-9083 Jason M. Fixler (PRINCIPAL_INVESTIGATOR) |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889-5600 | - |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | Site Public Contact 877-442-3324 Jessica A. Pollard (PRINCIPAL_INVESTIGATOR) |
| C S Mott Children's Hospital | Ann Arbor | Michigan | 48109 | Site Public Contact 800-865-1125 Joshua W. Goldman (PRINCIPAL_INVESTIGATOR) |
| Children's Hospital of Michigan | Detroit | Michigan | 48201 | Site Public Contact Meret Henry (PRINCIPAL_INVESTIGATOR) |
| Michigan State University | East Lansing | Michigan | 48823 | - |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | Kathleen Y. Butler (PRINCIPAL_INVESTIGATOR) |
| Bronson Methodist Hospital | Kalamazoo | Michigan | 49007 | Kathleen Y. Butler (PRINCIPAL_INVESTIGATOR) |
| Corewell Health Children's | Royal Oak | Michigan | 48073 | Site Public Contact 248-551-7695 Marie V. Nelson (PRINCIPAL_INVESTIGATOR) |
| Children's Hospitals and Clinics of Minnesota - Minneapolis | Minneapolis | Minnesota | 55404 | Michael K. Richards (PRINCIPAL_INVESTIGATOR) |
| University of Minnesota/Masonic Cancer Center | Minneapolis | Minnesota | 55455 | Site Public Contact 612-624-2620 Peter M. Gordon (PRINCIPAL_INVESTIGATOR) |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | Site Public Contact 855-776-0015 Wendy Allen-Rhoades (PRINCIPAL_INVESTIGATOR) |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | - |
| University of Missouri Children's Hospital | Columbia | Missouri | 65212 | Barbara A. Gruner (PRINCIPAL_INVESTIGATOR) |
| Children's Mercy Hospitals and Clinics | Kansas City | Missouri | 64108 | Kevin F. Ginn (PRINCIPAL_INVESTIGATOR) |
| Cardinal Glennon Children's Medical Center | St Louis | Missouri | 63104 | Site Public Contact 314-268-4000 William S. Ferguson (PRINCIPAL_INVESTIGATOR) |
| Mercy Hospital Saint Louis | St Louis | Missouri | 63141 | Site Public Contact 314-251-7066 Robin D. Hanson (PRINCIPAL_INVESTIGATOR) |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Laura G. Schuettpelz (PRINCIPAL_INVESTIGATOR) |
| Children's Hospital and Medical Center of Omaha | Omaha | Nebraska | 68114 | Site Public Contact 402-955-3949 Jill C. Beck (PRINCIPAL_INVESTIGATOR) |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | Jill C. Beck (PRINCIPAL_INVESTIGATOR) |
| Alliance for Childhood Diseases/Cure 4 the Kids Foundation | Las Vegas | Nevada | 89135 | Alan K. Ikeda (PRINCIPAL_INVESTIGATOR) |
| Summerlin Hospital Medical Center | Las Vegas | Nevada | 89144 | Alan K. Ikeda (PRINCIPAL_INVESTIGATOR) |
| Renown Regional Medical Center | Reno | Nevada | 89502 | Alan K. Ikeda (PRINCIPAL_INVESTIGATOR) |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center | Lebanon | New Hampshire | 03756 | Angela Ricci (PRINCIPAL_INVESTIGATOR) |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | Site Public Contact 551-996-2897 Jing Chen (PRINCIPAL_INVESTIGATOR) |
| Morristown Medical Center | Morristown | New Jersey | 07960 | Site Public Contact 973-971-5900 Kathryn L. Laurie (PRINCIPAL_INVESTIGATOR) |
| Jersey Shore Medical Center | Neptune City | New Jersey | 07753 | Site Public Contact 732-776-4240 Jing Chen (PRINCIPAL_INVESTIGATOR) |
| Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital | New Brunswick | New Jersey | 08903 | Site Public Contact 732-235-8675 Richard A. Drachtman (PRINCIPAL_INVESTIGATOR) |
| Saint Peter's University Hospital | New Brunswick | New Jersey | 08901 | Nibal A. Zaghloul (PRINCIPAL_INVESTIGATOR) |
| Saint Joseph's Regional Medical Center | Paterson | New Jersey | 07503 | Alissa Kahn (PRINCIPAL_INVESTIGATOR) |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87106 | Jessica M. Valdez (PRINCIPAL_INVESTIGATOR) |
| Albany Medical Center | Albany | New York | 12208 | Site Public Contact 518-262-5513 Lauren R. Weintraub (PRINCIPAL_INVESTIGATOR) |
| Maimonides Medical Center | Brooklyn | New York | 11219 | Site Public Contact 718-765-2500 Mahmut Y. Celiker (PRINCIPAL_INVESTIGATOR) |
| NYU Langone Hospital - Long Island | Mineola | New York | 11501 | Chana L. Glasser (PRINCIPAL_INVESTIGATOR) |
| The Steven and Alexandra Cohen Children's Medical Center of New York | New Hyde Park | New York | 11040 | Site Public Contact 718-470-3460 Arlene S. Redner (PRINCIPAL_INVESTIGATOR) |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | Site Public Contact Elizabeth A. Raetz (PRINCIPAL_INVESTIGATOR) |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Site Public Contact 212-639-7592 Maria Luisa Sulis (PRINCIPAL_INVESTIGATOR) |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | Nobuko Hijiya (PRINCIPAL_INVESTIGATOR) |
| University of Rochester | Rochester | New York | 14642 | - |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | Site Public Contact 800-862-2215 Laura E. Hogan (PRINCIPAL_INVESTIGATOR) |
| State University of New York Upstate Medical University | Syracuse | New York | 13210 | Site Public Contact 315-464-5476 Melanie A. Comito (PRINCIPAL_INVESTIGATOR) |
| Montefiore Medical Center - Moses Campus | The Bronx | New York | 10467 | - |
| New York Medical College | Valhalla | New York | 10595 | Site Public Contact 914-594-3794 Jessica C. Hochberg (PRINCIPAL_INVESTIGATOR) |
| Mission Hospital | Asheville | North Carolina | 28801 | Douglas J. Scothorn (PRINCIPAL_INVESTIGATOR) |
| UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | Thomas B. Alexander (PRINCIPAL_INVESTIGATOR) |
| Carolinas Medical Center/Levine Cancer Institute | Charlotte | North Carolina | 28203 | Site Public Contact 800-804-9376 Joel A. Kaplan (PRINCIPAL_INVESTIGATOR) |
| Novant Health Presbyterian Medical Center | Charlotte | North Carolina | 28204 | Holly Edington (PRINCIPAL_INVESTIGATOR) |
| Duke University Medical Center | Durham | North Carolina | 27710 | Site Public Contact 888-275-3853 Jessica M. Sun (PRINCIPAL_INVESTIGATOR) |
| East Carolina University | Greenville | North Carolina | 27834 | Andrea R. Whitfield (PRINCIPAL_INVESTIGATOR) |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | Site Public Contact 336-713-6771 Sarah Supples (PRINCIPAL_INVESTIGATOR) |
| Sanford Broadway Medical Center | Fargo | North Dakota | 58122 | Samuel J. Milanovich (PRINCIPAL_INVESTIGATOR) |
| Children's Hospital Medical Center of Akron | Akron | Ohio | 44308 | Site Public Contact 330-543-3193 Erin Wright (PRINCIPAL_INVESTIGATOR) |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | Lauren Pommert (PRINCIPAL_INVESTIGATOR) |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | - |
| Rainbow Babies and Childrens Hospital | Cleveland | Ohio | 44106 | Site Public Contact 216-844-5437 Duncan S. Stearns (PRINCIPAL_INVESTIGATOR) |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | Mark A. Ranalli (PRINCIPAL_INVESTIGATOR) |
| Dayton Children's Hospital | Dayton | Ohio | 45404 | Site Public Contact 800-228-4055 Jordan M. Wright (PRINCIPAL_INVESTIGATOR) |
| ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital | Toledo | Ohio | 43606 | Jamie L. Dargart (PRINCIPAL_INVESTIGATOR) |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | Rene Y. McNall-Knapp (PRINCIPAL_INVESTIGATOR) |
| Legacy Emanuel Children's Hospital | Portland | Oregon | 97227 | Site Public Contact 503-413-2560 Jason M. Glover (PRINCIPAL_INVESTIGATOR) |
| Oregon Health and Science University | Portland | Oregon | 97239 | Bill H. Chang (PRINCIPAL_INVESTIGATOR) |
| Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | 18103 | Jacob A. Troutman (PRINCIPAL_INVESTIGATOR) |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | Jagadeesh Ramdas (PRINCIPAL_INVESTIGATOR) |
| Penn State Children's Hospital | Hershey | Pennsylvania | 17033 | Site Public Contact 717-531-6012 Lisa M. McGregor (PRINCIPAL_INVESTIGATOR) |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | Sarah K. Tasian (PRINCIPAL_INVESTIGATOR) |
| Saint Christopher's Hospital for Children | Philadelphia | Pennsylvania | 19134 | Site Public Contact 215-427-8991 Gregory E. Halligan (PRINCIPAL_INVESTIGATOR) |
| Children's Hospital of Pittsburgh of UPMC | Pittsburgh | Pennsylvania | 15224 | Erika Friehling (PRINCIPAL_INVESTIGATOR) |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | Site Public Contact 401-444-1488 Bradley DeNardo (PRINCIPAL_INVESTIGATOR) |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | Jacqueline M. Kraveka (PRINCIPAL_INVESTIGATOR) |
| Prisma Health Richland Hospital | Columbia | South Carolina | 29203 | Stuart L. Cramer (PRINCIPAL_INVESTIGATOR) |
| BI-LO Charities Children's Cancer Center | Greenville | South Carolina | 29605 | Aniket Saha (PRINCIPAL_INVESTIGATOR) |
| Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota | 57117-5134 | Kayelyn J. Wagner (PRINCIPAL_INVESTIGATOR) |
| East Tennessee Childrens Hospital | Knoxville | Tennessee | 37916 | Site Public Contact 865-541-8266 Susan E. Spiller (PRINCIPAL_INVESTIGATOR) |
| Saint Jude Children's Research Hospital | Memphis | Tennessee | 38105 | Seth E. Karol (PRINCIPAL_INVESTIGATOR) |
| The Children's Hospital at TriStar Centennial | Nashville | Tennessee | 37203 | Site Public Contact 615-342-1919 Clinton M. Carroll (PRINCIPAL_INVESTIGATOR) |
| Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | 37232 | Site Public Contact 800-811-8480 Christine M. Smith (PRINCIPAL_INVESTIGATOR) |
| Dell Children's Medical Center of Central Texas | Austin | Texas | 78723 | Shannon M. Cohn (PRINCIPAL_INVESTIGATOR) |
| Driscoll Children's Hospital | Corpus Christi | Texas | 78411 | Nkechi I. Mba (PRINCIPAL_INVESTIGATOR) |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | Site Public Contact 972-566-5588 Maurizio L. Ghisoli (PRINCIPAL_INVESTIGATOR) |
| UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | 75390 | Kathleen (Wiertel) Ludwig (PRINCIPAL_INVESTIGATOR) |
| El Paso Children's Hospital | El Paso | Texas | 79905 | Benjamin Carcamo (PRINCIPAL_INVESTIGATOR) |
| Cook Children's Medical Center | Fort Worth | Texas | 76104 | Holly Pacenta (PRINCIPAL_INVESTIGATOR) |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Houston | Texas | 77030 | Michele S. Redell (PRINCIPAL_INVESTIGATOR) |
| M D Anderson Cancer Center | Houston | Texas | 77030 | Najat C. Daw (PRINCIPAL_INVESTIGATOR) |
| Covenant Children's Hospital | Lubbock | Texas | 79410 | Kishor M. Bhende (PRINCIPAL_INVESTIGATOR) |
| UMC Cancer Center / UMC Health System | Lubbock | Texas | 79415 | Site Public Contact 806-775-8590 Erin K. Barr (PRINCIPAL_INVESTIGATOR) |
| Children's Hospital of San Antonio | San Antonio | Texas | 78207 | Julie Voeller (PRINCIPAL_INVESTIGATOR) |
| Methodist Children's Hospital of South Texas | San Antonio | Texas | 78229 | Jose M. Esquilin (PRINCIPAL_INVESTIGATOR) |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | Allison C. Grimes (PRINCIPAL_INVESTIGATOR) |
| Primary Children's Hospital | Salt Lake City | Utah | 84113 | Site Public Contact 801-585-5270 David S. Mangum (PRINCIPAL_INVESTIGATOR) |
| University of Virginia Cancer Center | Charlottesville | Virginia | 22908 | Brian C. Belyea (PRINCIPAL_INVESTIGATOR) |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042 | Robin Y. Dulman (PRINCIPAL_INVESTIGATOR) |
| Children's Hospital of The King's Daughters | Norfolk | Virginia | 23507 | Melissa S. Mark (PRINCIPAL_INVESTIGATOR) |
| VCU Massey Comprehensive Cancer Center | Richmond | Virginia | 23298 | Jordyn R. Griffin (PRINCIPAL_INVESTIGATOR) |
| Carilion Children's | Roanoke | Virginia | 24014 | Erwood G. Edwards (PRINCIPAL_INVESTIGATOR) |
| Seattle Children's Hospital | Seattle | Washington | 98105 | Site Public Contact 866-987-2000 Sarah E. Leary (PRINCIPAL_INVESTIGATOR) |
| Providence Sacred Heart Medical Center and Children's Hospital | Spokane | Washington | 99204 | Judy L. Felgenhauer (PRINCIPAL_INVESTIGATOR) |
| Madigan Army Medical Center | Tacoma | Washington | 98431 | Melissa A. Forouhar (PRINCIPAL_INVESTIGATOR) |
| Mary Bridge Children's Hospital and Health Center | Tacoma | Washington | 98405 | Robert G. Irwin (PRINCIPAL_INVESTIGATOR) |
| West Virginia University Healthcare | Morgantown | West Virginia | 26506 | Ashley E. Meyer (PRINCIPAL_INVESTIGATOR) |
| University of Wisconsin Carbone Cancer Center - University Hospital | Madison | Wisconsin | 53792 | Kenneth B. De Santes (PRINCIPAL_INVESTIGATOR) |
| Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | 54449 | Michelle A. Manalang (PRINCIPAL_INVESTIGATOR) |
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