Paid Clinical Trials in Alabama

Alabama has 1,359 paid clinical trials enrolling now across cities including Birmingham, Mobile and Huntsville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Alabama include University of Alabama at Birmingham, National Cancer Institute (NCI) and AstraZeneca, running studies across oncology, cardiology, neurology, and more. The most actively recruiting conditions are Breast Cancer, Heart Failure, Obesity, Hypertension — browse the full list or use the filters to match your diagnosis. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

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1,359 clinical trials

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Low-Dose Naltrexone For ME/CFS: Dose-Finding

for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
1 location in Birmingham
Sponsor: University of Alabama at Birmingham
Sex: All·Age: 18 - 65
Code: NCT07285473·Phase 2·Not Yet Recruiting

TearCare in Young Adults

for Meibomian Gland Dysfunction (Disorder)
1 location in Birmingham
Sponsor: University of Alabama at Birmingham
Sex: All·Age: 18 - 29
Code: NCT07579156·Not Yet Recruiting

About research studies in Alabama

Alabama has approximately 1,359 recruiting research studies across a wide range of therapeutic areas. Alabama hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.

Common conditions studied in Alabama

  • Breast Cancer (22 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
  • Heart Failure (21 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
  • Obesity (20 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
  • Hypertension (15 active studies). Hypertension research tests new antihypertensive drug classes, renal denervation devices, and fixed-dose combinations for resistant disease.
  • Multiple Myeloma (15 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
  • Sickle Cell Disease (14 active studies). Sickle cell disease studies test gene therapies, gene editing, and new small molecules aimed at reducing pain crises and organ damage.

Leading research sponsors in Alabama

  • University of Alabama at Birmingham
  • National Cancer Institute (NCI)
  • AstraZeneca
  • Children's Oncology Group
  • Eli Lilly and Company

Local regulations and guidelines

Clinical trials in Alabama are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Alabama research additionally follows state public health department oversight and any applicable state privacy statutes.

Compensation & what to expect

How payment typically works
Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
Healthy volunteers
Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Alabama. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
What's included beyond payment
Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
Travel and time
Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
Asking about compensation
Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.

How to find a clinical trial in Alabama

Hipa.ai aggregates every recruiting study in Alabama from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.

Frequently asked questions

How many paid clinical trials are currently recruiting in Alabama?

There are approximately 1,359 recruiting clinical trials in Alabama listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Alabama pay participants?

Most recruiting trials in Alabama compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Alabama?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Alabama?

The most common conditions under active study in Alabama include Breast Cancer (22), Heart Failure (21), Obesity (20), Hypertension (15), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Alabama?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Alabama on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Alabama?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Browse more clinical trials

All cities in Alabama

Birmingham, AL(1,064)Mobile, AL(123)Huntsville, AL(91)Dothan, AL(46)Fairhope, AL(36)Tuscaloosa, AL(28)Auburn, AL(27)Daphne, AL(24)Anniston, AL(17)Homewood, AL(17)Montgomery, AL(17)Cullman, AL(15)Saraland, AL(13)Alexander City, AL(12)Foley, AL(10)Sheffield, AL(9)Alabaster, AL(7)Guntersville, AL(6)Athens, AL(4)Centreville, AL(3)Decatur, AL(3)Jasper, AL(3)Vestavia Hills, AL(3)Bessemer, AL(2)Gardendale, AL(2)Pelham, AL(2)South Birmingham, AL(2)Andalusia, AL(1)Bay Minette, AL(1)Burmingham, AL(1)Fort Novosel, AL(1)Hobson City, AL(1)Hoover, AL(1)Irondale, AL(1)Madison, AL(1)Multiple Locations, AL(1)Opelika, AL(1)Scottsboro, AL(1)Trussville, AL(1)

Related healthcare resources in Alabama

Behavioral health news in AlabamaLatest Alabama clinical trials research report

Trials by condition in Alabama

Breast Cancer· 22Heart Failure· 21Obesity· 20Hypertension· 15Multiple Myeloma· 15Sickle Cell Disease· 14Ovarian Cancer· 13