Clinical Trials at Johns Hopkins University

As of June 2026, 189 paid clinical trials are recruiting at Johns Hopkins University, located at Brain Injury Outcomes at Johns Hopkins University, 750 E Pratt St, Baltimore, MD 21202, phone (410) 361-7999 in Baltimore, Maryland. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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189 clinical trials at Johns Hopkins University

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Efficacy and Safety of Tirzepatide Versus Placebo or Lisdexamfetamine Dimesylate for Binge-Eating Disorder

for Obesity and Overweight

Drug: Tirzepatide

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06847399·Phase 2·Recruiting

Apply to this trial

Intent of Surgery for IPMN

for Intraductal Papillary Mucinous Neoplasm

8 locations incl. Phoenix

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT07216521·Recruiting

Apply to this trial

A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

for Metastatic Castration-resistant Prostate Neoplasms

Drug: Pasritamig

50 locations incl. La Jolla

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT07164443·Phase 3·Recruiting

Apply to this trial

Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

for Neurofibromatosis 1

Drug: Selumetinib

15 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 1 - 8

Code: NCT06188741·Phase 2·Recruiting

Apply to this trial

Administering NMT to Reestablish Infant Nasal Microbiome Diversity Following Intranasal Mupirocin Treatment

for Staphylococcal Aureus Infection

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 0 - 60·Accepts healthy volunteers

Code: NCT06805994·Phase 1·Recruiting

Apply to this trial

Change in Social Media Use and Well-being Among College Students Receiving a Two-week Exercise or Mindfulness Intervention

for Social Media Addiction

1 location in Baltimore

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07097545·Recruiting

Apply to this trial

Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

for Familial Adenomatous Polyposis (FAP)

18 locations incl. Arcadia

Sponsor: Rapamycin Holdings Inc.

Sex: All·Age: 18+

Code: NCT06950385·Phase 3·Recruiting

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Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

31 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting

Apply to this trial

Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Low-grade NMIBC

28 locations incl. Homewood

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06995677·Phase 2·Recruiting

Apply to this trial

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

for Heart Failure With Preserved Ejection Fraction

106 locations incl. Birmingham

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07037459·Phase 3·Recruiting

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A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

for Pancreatic Ductal Adenocarcinoma

13 locations incl. Los Angeles

Sponsor: Verastem, Inc.

Sex: All·Age: 18+

Code: NCT07020221·Phase 1, Phase 2·Recruiting

Apply to this trial

Effect of the HCC Liver-Link Intervention

for HCC

2 locations incl. Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 75

Code: NCT06728293·Recruiting

Apply to this trial

Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin

for Ototoxicity, Drug-Induced

7 locations incl. San Francisco

Sponsor: Kevin Winthrop

Sex: All·Age: 18 - 80

Code: NCT05730283·Phase 2·Recruiting

Apply to this trial

Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)

for Chronic Inducible Urticaria

27 locations incl. Birmingham

Sponsor: Blueprint Medicines Corporation

Sex: All·Age: 18+

Code: NCT06931405·Phase 2·Recruiting

Apply to this trial

Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia

for Severe Aplastic Anemia

25 locations incl. Birmingham

Sponsor: Medical College of Wisconsin

Sex: All·Age: 3 - 75

Code: NCT06517641·Phase 2·Recruiting

Apply to this trial

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

for Amyloidosis

Drug: Acoramidis

39 locations incl. La Jolla

Sponsor: Eidos Therapeutics, a BridgeBio company

Sex: All·Age: 18 - 75

Code: NCT06563895·Phase 3·Recruiting

Apply to this trial

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

for Cystic Fibrosis

18 locations incl. Birmingham

Sponsor: Boston Children's Hospital

Sex: All·Age: 6+

Code: NCT06683092·Recruiting

Apply to this trial

CardiolRx in Recurrent Pericarditis (MAVERIC Phase-3)

for Recurrent Pericarditis

21 locations incl. Phoenix

Sponsor: Cardiol Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06708299·Phase 3·Recruiting

Apply to this trial

Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis

for Osteonecrosis of the Femoral Head

10 locations incl. Los Angeles

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 90

Code: NCT06123481·Recruiting

Apply to this trial

Myofascial Dysfunction in Post Stroke Shoulder Pain

for Stroke

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06718413·Phase 2·Recruiting

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A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

for Gastrointestinal Stromal Tumor (GIST)

32 locations incl. Birmingham

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06655246·Phase 1·Recruiting

Apply to this trial

Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

for Suicide, Attempted

6 locations incl. St. Petersburg

Sponsor: Johns Hopkins University

Sex: All·Age: 12 - 24

Code: NCT06151158·Recruiting

Apply to this trial

Embryonal Tumor With Multilayered Rosettes

for Embryonal Tumor With Multilayered Rosettes

7 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: All ages

Code: NCT06861244·Phase 2·Recruiting

Apply to this trial

Rilonacept in Subjects With Cardiac Sarcoidosis

for Cardiac Sarcoidosis

2 locations incl. Baltimore

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80

Code: NCT06660732·Phase 2·Recruiting

Apply to this trial

SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization

for Prostate Cancer

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18 - 100

Code: NCT06389097·Recruiting

Apply to this trial

Remote Sputum Collection in Cystic Fibrosis

for Cystic Fibrosis

3 locations incl. Denver

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06950892·Recruiting

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A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Patients With Bladder Cancer (MK-2870-027)

for Non-Muscle Invasive Bladder Cancer

4 locations incl. Bakersfield

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06637423·Phase 1, Phase 2·Recruiting

Apply to this trial

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

for Asthma

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06273072·Phase 2·Recruiting

Apply to this trial

Preliminary Characterization of Commercial Kratom Extract Products

for Kratom Pharmacodynamics

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06640569·Recruiting

Apply to this trial

Strategies to AchieVe Viral Suppression for Youth With HIV

for Human Immunodeficiency Virus (HIV) Infection

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 12 - 30

Code: NCT06886971·Recruiting

Apply to this trial

Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

for Heart Failure

6 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT06517186·Recruiting

Apply to this trial

Achieving Cardiovascular Health Equity in Community Mental Health: Optimizing Implementation Strategies

for Cardiovascular Risk Factors

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06674616·Enrolling By Invitation

Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06401577·Recruiting

Apply to this trial

Social Needs App for Oncology Patients Phase II

for Cancer

3 locations incl. Baltimore

Sponsor: JHSPH Center for Clinical Trials

Sex: All·Age: 18+

Code: NCT06688513·Enrolling By Invitation

A Multi-Site Break Through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib

for Acute Myeloid Leukemia

Drug: Venetoclax

4 locations incl. Baltimore

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 12+

Code: NCT06284486·Phase 1, Phase 2·Recruiting

Apply to this trial

text4FATHER R21: Social Media - Efficacy Trial

for Fathers

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06289101·Recruiting

Apply to this trial

Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome

for Staphylococcus Aureus

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 0 - 60·Accepts healthy volunteers

Code: NCT06283355·Phase 1·Recruiting

Apply to this trial

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

for Lung Transplant

18 locations incl. Los Angeles

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06399302·Recruiting

Apply to this trial

Resilient, Engaged, and Connected Study

for Parenting

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06197997·Recruiting

Apply to this trial

SCRIPT: Sickle Cell Risk in Pregnancy Tool

for Sickle Cell Disease

1 location in Baltimore

Sponsor: Mount Sinai Hospital, Canada

Sex: Female·Age: 16 - 60

Code: NCT06529042·Enrolling By Invitation