Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

Part of paid clinical trials in Los Angeles, California.

Sponsor: Duke University
Study ID: NCT06399302
Status: Recruiting

Conditions

Lung Transplant Failure
Lung Transplant Rejection
Lung Transplant; Complications
Lung Transplant; Infection or Inflammation

Eligibility Criteria

Sex: ALL
Age: 18 Years - N/A
Healthy Volunteers: Not accepted

Study Details

This project aims to collect detailed clinical data, blood samples, and patient-reported outcomes from 2,600 lung transplant candidates, donors, and recipients at Lung Transplant Centers. The goal is to create a robust resource for various research objectives, including studying the impact of variations in donor and medical practices on clinical outcomes. The project also seeks to identify serum biomarkers associated with or predictive of specific post-transplant complications and conditions.

Key Dates

Start date: Sep 3, 2024
Status verified: Jul 2025
Primary completion: Jun 30, 2027
Completion: Jun 30, 2027

Study Design

Enrollment: 2,600 participants (estimated)

Arms

Arm: Lung transplant donors and recipients
Lung transplant donors and adult (18 years and up) lung transplant candidates and recipients

Primary Outcome Measure

Number of participants enrolled and critical variable completeness [ Time Frame: 3 years ]

Central Contacts

Allyn Damman
919-259-4414
[email protected]
Carl Schuler, RN
919-695-2721
[email protected]

Locations (18)

Facility	City	State	ZIP	Site coordinators
University of California Los Angeles	Los Angeles	California	90095	Jennifer Perez [email protected] 000-000-0000 Shahrzad Lari [email protected] John Belperio (PRINCIPAL_INVESTIGATOR)
University of California at San Francisco	San Francisco	California	94143	Jon Singer, MD, MS [email protected] 415-476-6030 Legna Betancourt [email protected] 415-476-8073
Stanford University Medical Center	Stanford	California	94305	Gundeep S. Dhillon, MD [email protected] (650) 723-6381 Mykah D. Llaguno Dela Rima [email protected]
University of Miami	Miami	Florida	33136	Moni Lissett [email protected] 305-355-5418 Walter Brauchle [email protected] Juan Fernandez Castillo (PRINCIPAL_INVESTIGATOR)
Johns Hopkins University	Baltimore	Maryland	21205	Joby Matthew [email protected] 443-416-7573 Kelley Matt [email protected] Christian Merlo (PRINCIPAL_INVESTIGATOR)
Brigham and Womens Hospital	Boston	Massachusetts	02115	Nusrath Abdulla [email protected] 857-763-8868 Sam Wong [email protected] 000-000-0000 Hilary Goldberg (PRINCIPAL_INVESTIGATOR)
University of Michigan	Ann Arbor	Michigan	48109	Jules Lin [email protected] 734-936-5738 Nicholas Demchuk [email protected] 734-936-3502
University of Minnesota	Minneapolis	Minnesota	55455	Adeline Beck [email protected] 000-000-0000 Henry Madden [email protected] 612-725-5665 Stephen Huddleston (PRINCIPAL_INVESTIGATOR)
Columbia University	New York	New York	10032	Shreena Patel [email protected] 973-722-6835 Leonor Suarez [email protected] 646-528-9006 Luke Benvenuto (PRINCIPAL_INVESTIGATOR)
New York University	New York	New York	10016	Shushaunna Bennett [email protected] 646-630-2408 Cecilia Deterville [email protected] Stephanie Chang (PRINCIPAL_INVESTIGATOR)
Duke University Medical Center	Durham	North Carolina	27710	Laurie Snyder, MD, MHS [email protected] 919-684-2240 Erika Buckley [email protected] 919-660-7222
University of Pennsylvania	Philadelphia	Pennsylvania	19104	Jessica Johnson [email protected] 610-731-1661 Jason Christie (PRINCIPAL_INVESTIGATOR)
University of Pittsburgh Medical Center	Pittsburgh	Pennsylvania	15261	Ritchie Koshy [email protected] 412-802-8624 Amanda Zeng [email protected] 412-383-1818 John McDyer (PRINCIPAL_INVESTIGATOR)
Vanderbilt University Medical Center	Nashville	Tennessee	37232	Lisa Smithson [email protected] 615-875-8253 Tansy Gaines [email protected] 256-348-1431 Lorraine Ware (PRINCIPAL_INVESTIGATOR)
Houston Methodist Hospital, Texas Medical Center	Houston	Texas	77030	Howard J. Huang, MD [email protected] (713) 441-5451 Serene Shaham [email protected] 346-238-5653 Howard J. Huang, MD (PRINCIPAL_INVESTIGATOR)
Inova Fairfax Hospital	Falls Church	Virginia	22042	Thao-chi Vo [email protected] 703-776-8041 Edwinia Battle [email protected] 703-776-7691 Shambhu Aryal (PRINCIPAL_INVESTIGATOR)
University of Washington	Seattle	Washington	98109	Chelsea Schmitz [email protected] 916-247-5438 Michaela Blanchard [email protected] 408-834-2141 Michael Mulligan (PRINCIPAL_INVESTIGATOR)
University of Wisconsin Hospital and Clinics	Madison	Wisconsin	53792	Megan Devereaux [email protected] 000-000-0000 Melanie Nelson [email protected] 000-000-0000 Erin Lowery (PRINCIPAL_INVESTIGATOR)

Find similar trials in Los Angeles, CA

By research site

University of California Los Angeles· Los Angeles, CA University of California at San Francisco· San Francisco, CA Stanford University Medical Center· Stanford, CA University of Miami· Miami, FL Johns Hopkins University· Baltimore, MD Brigham and Womens Hospital· Boston, MA

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