Diagnostic and Therapeutic Applications of Microarrays in Lung Transplantation

Part of paid clinical trials in Phoenix, Arizona.

Sponsor
University of Alberta
Study ID
NCT02812290
Status
Recruiting
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Conditions

  • Lung Transplant Rejection

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Lung transplant biopsy bites. — PROCEDURE
    In the second phase of the study, two biopsy bites from the same patient will be collected to assess tissue sampling variability.

Study Details

Objective: To evaluate the potential impact of molecular phenotyping of transbronchial biopsies in lung transplant recipients with allograft dysfunction, and the potential for developing a safer endobronchial mucosal biopsy format.

Key Dates

Start date
May 31, 2016
Status verified
May 2026
Primary completion
Jun 30, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
700 participants (estimated)

Primary Outcome Measure

Report the molecular scores (probability) of lung transplant disease in a reference set of 600 transbronchial biopsies. [ Time Frame: two years ]

Central Contacts

Locations (4)

FacilityCityStateZIPSite coordinators
St. Joseph's Hospital and Medical Center 350 West Thomas Road, Floor 8HLTPhoenixArizona85013
Chanti F Smith
[email protected]
214-820-1771
Rajat Walia, MD (PRINCIPAL_INVESTIGATOR)
University of Maryland School of MedicineBaltimoreMaryland21201-
Division of Pulmonary and Critical Care, Washington University School of MedicineSt LouisMissouri63110-
University of Texas at San AntonioSan AntonioTexas21201-

Find similar trials in Phoenix, AZ

By research site
St. Joseph's Hospital and Medical Center 350 West Thomas Road, Floor 8HLT· Phoenix, AZUniversity of Maryland School of Medicine· Baltimore, MDDivision of Pulmonary and Critical Care, Washington University School of Medicine· St Louis, MOUniversity of Texas at San Antonio· San Antonio, TX

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