Intent of Surgery for IPMN

Part of paid clinical trials in Phoenix, Arizona.

Sponsor
NYU Langone Health
Study ID
NCT07216521
Status
Recruiting
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Conditions

  • Intraductal Papillary Mucinous Neoplasm

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

This multicenter retrospective observational cohort study seeks to: 1. Classify surgical intent in patients with resected Intraductal Papillary Mucinous Neoplasms (IPMN) and quantify the proportion of IPMN-associated cancers diagnosed as overt pancreatic cancer with incidental IPMN association on pathology. 2. Compare clinicopathologic features and outcomes between surveillance-detected and incidentally detected IPMN-derived pancreatic cancers. 3. Revise and redefine risk features limited to patients undergoing surgery for IPMN-related indications, identifying optimal predictors of malignant IPMN (high-grade dysplasia or invasive cancer).

Key Dates

Start date
Sep 15, 2025
Status verified
Oct 2025
Primary completion
Dec 31, 2025
Completion
Dec 31, 2025

Study Design

Enrollment
2,000 participants (estimated)

Arms

  • Arm: Patients who underwent surgical resection for IPMN
    Pathology reports on patients (18 years old of greater) who underwent surgical resection for IPMN will be accessed for analysis.

Primary Outcome Measure

Grade of IPMN on Final Pathology [ Time Frame: Day 0 (Retrospective Analysis) ]

Central Contacts

Locations (8)

FacilityCityStateZIPSite coordinators
Mayo ClinicPhoenixArizona85054
Zhi Fong, MD, PhD (PRINCIPAL_INVESTIGATOR)
Johns Hopkins UniversityBaltimoreMaryland21287
Jin He, MD, PhD (PRINCIPAL_INVESTIGATOR)
Massachusetts General HospitalBostonMassachusetts02114
Carlos Fernandez-del Castillo, MD (PRINCIPAL_INVESTIGATOR)
Mayo ClinicRochesterMinnesota55905
Cornelius Thiels, D.O., MBA (PRINCIPAL_INVESTIGATOR)
Memorial Sloan KetteringNew YorkNew York10022
Kevin Soares, MD (PRINCIPAL_INVESTIGATOR)
NYU Langone HealthNew YorkNew York10016
Greg Sacks, MD MPH PhD (PRINCIPAL_INVESTIGATOR)
Duke UniversityDurhamNorth Carolina27710
Daniel Nussbaum, MD (PRINCIPAL_INVESTIGATOR)
MD Anderson Cancer CenterHoustonTexas77030
Michael Kim, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Phoenix, AZ

By research site
Mayo Clinic· Phoenix, AZJohns Hopkins University· Baltimore, MDMassachusetts General Hospital· Boston, MAMayo Clinic· Rochester, MNMemorial Sloan Kettering· New York, NYNYU Langone Health· New York, NY

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