Metformin IN Asthma for Overweight and Obese Individuals (MINA)

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
Johns Hopkins University
Study ID
NCT06273072
Phase
PHASE2
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Metformin hydrochloride extended-release tablets — DRUG
    titrated to 2000 mg once daily
  • Visually identical placebo Metformin hydrochloride extended-release tablets — DRUG
    placebo

Study Details

This is a randomized clinical trial of metformin among overweight or obese adults with not well-controlled asthma despite maintenance inhaler therapy.

Key Dates

Start date
Dec 9, 2024
Status verified
Jan 2026
Primary completion
Sep 30, 2026
Completion
Dec 31, 2028

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Metformin hydrochloride extended-release tablets
    Metformin hydrochloride extended-release tablets 2000 mg once daily
  • Placebo Comparator: Visually identical placebo tablets
    Placebo tablet once daily

Primary Outcome Measure

Number of completed telemedicine visits [ Time Frame: Baseline to week 24 ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Johns Hopkins UniversityBaltimoreMaryland21224
Rachelle Koehl
[email protected]
410-955-1530
Meredith C McCormack, M.D., M.H.S. (PRINCIPAL_INVESTIGATOR)
Baylor College of MedicineHoustonTexas77030
Tianshi D Wu, M.D., M.H.S.

Find similar trials in Baltimore, MD

By condition
AsthmaObesity / overweight
By specialty
PulmonologyLung diseaseEndocrinologyMetabolic healthWeight loss
By research site
Johns Hopkins University· Baltimore, MDBaylor College of Medicine· Houston, TX

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