Paid Clinical Trials in Tennessee

Tennessee has 2,156 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,156 clinical trials

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Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1)

for Hidradenitis Suppurativa

Drug: Ruxolitinib

59 locations incl. Phoenix

Sponsor: Incyte Corporation

Sex: All·Age: 12+

Code: NCT06959225·Phase 3·Recruiting

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Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

for Pulmonary Disease, Chronic Obstructive

Drug: Depemokimab

55 locations incl. Sheffield

Sponsor: GlaxoSmithKline

Sex: All·Age: 40 - 80

Code: NCT06961214·Phase 3·Recruiting

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TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas

for Lymphoma

6 locations incl. Palo Alto

Sponsor: Treeline Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07082803·Phase 1·Recruiting

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A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Drug: Pegcetacoplan

68 locations incl. Gilbert

Sponsor: Apellis Pharmaceuticals, Inc.

Sex: All·Age: 60+

Code: NCT07215390·Phase 2·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701682·Phase 2·Recruiting

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A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

for Rheumatoid Arthritis

52 locations incl. Peoria

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06972446·Phase 2·Recruiting

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A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

for Prostate Cancer

10 locations incl. Huntsville

Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male·Age: 18+

Code: NCT07005154·Phase 2·Recruiting

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A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

for Graves' Disease

Drug: IMVT-1402

33 locations incl. Tucson

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 75

Code: NCT07018323·Phase 2·Recruiting

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Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

for Childhood Astrocytoma

20 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 22

Code: NCT06894979·Phase 1·Recruiting

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A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

for Parkinsons Disease (PD)

31 locations incl. Sun City

Sponsor: BlueRock Therapeutics

Sex: All·Age: 45 - 75

Code: NCT06944522·Phase 3·Recruiting

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An Observational Study of Individuals With Isolated Dystonia

for Isolated/Primary Dystonia That Affects More Than One Region of the Body

29 locations incl. Scottsdale

Sponsor: Vima Therapeutics

Sex: All·Age: 12 - 65

Code: NCT07111663·Recruiting

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Revealing Information Genuinely & Honestly Across Time - Communication Preferences Visit

for Cancer

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT06993688·Recruiting

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Neonatal Platelet Transfusion Threshold Trial

for Thrombocytopenia

20 locations incl. Birmingham

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: 1 Hour - 48 Hours·Accepts healthy volunteers

Code: NCT06676904·Recruiting

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Milrinone for Prevention of Post-ligation Cardiac Syndrome Trial

for Post-ligation Cardiac Syndrome

19 locations incl. Birmingham

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: Up to 3 Months

Code: NCT06679855·Phase 3·Recruiting

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Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC

for Non-small Cell Lung Cancer

5 locations incl. Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06745882·Phase 2·Recruiting

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Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

for Myelodysplastic Syndrome

138 locations incl. Berkeley

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06577441·Phase 2·Recruiting

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Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

for Childhood Fibrolamellar Carcinoma

21 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 39

Code: NCT06620302·Phase 1, Phase 2·Recruiting

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A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer

for Neoplasms, Prostate

2 locations incl. Denver

Sponsor: GlaxoSmithKline

Sex: Male·Age: 18+

Code: NCT06990880·Phase 1, Phase 2·Recruiting

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A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

34 locations incl. Laguna Hills

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06943872·Phase 3·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Cohort B: paridiprubart

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701669·Phase 2·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06703073·Phase 2·Recruiting

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Reverse Shoulder Arthroplasty vs Rotator Cuff Repair for 60+

for Shoulder Injuries

1 location in Germantown

Sponsor: Campbell Clinic

Sex: All·Age: 60 - 95

Code: NCT06848023·Enrolling By Invitation

REVEAL: A Phase 3 Study of ION582 in Angelman Syndrome

for Angelman Syndrome

15 locations incl. Los Angeles

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 2 - 50

Code: NCT06914609·Phase 3·Recruiting

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Project PAIR: Parent-implemented Articulation Intervention With Recast

for Hearing Impaired Children

1 location in Nashville

Sponsor: Vanderbilt University

Sex: All·Age: 4 - 10

Code: NCT06936696·Recruiting

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Clinical Trial Protocol: Alzheimer's Dementia Underlying Encephalopathy

for Alzheimer Dementia

6 locations incl. Crossville

Sponsor: Covenant Health, US

Sex: All·Age: 60 - 90

Code: NCT07222280·Recruiting

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Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

for Agitation

53 locations incl. Homewood

Sponsor: Celgene

Sex: All·Age: 55 - 90

Code: NCT06808984·Phase 2·Recruiting

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ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

for Autosomal Dominant Polycystic Kidney Disease

35 locations incl. Garden Grove

Sponsor: Calico Life Sciences LLC

Sex: All·Age: 18 - 55

Code: NCT06902558·Phase 2·Recruiting

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A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich's Ataxia

for Friedreich Ataxia

7 locations incl. Los Angeles

Sponsor: Biogen

Sex: All·Age: 2 - 15

Code: NCT06953583·Phase 3·Recruiting

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Attentional Mechanisms in SCD

for Subjective Cognitive Decline

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT06002477·EARLY_Phase 1·Recruiting

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Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for Acute Leukemia of Ambiguous Lineage

Drug: Venetoclax

112 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 365 Days

Code: NCT06317662·Phase 2·Recruiting

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A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

for Multiple Sclerosis Spasticity

15 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: 18 - 70

Code: NCT06782490·Phase 2·Recruiting

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A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema

for Macular Edema

23 locations incl. Arcadia

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06962839·Phase 2·Recruiting

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A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

for Leukemia, Myeloid, Acute

Drug: Venetoclax

50 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06852222·Phase 3·Recruiting

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A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome

for Dravet Syndrome

Drug: zorevunersen

31 locations incl. Phoenix

Sponsor: Stoke Therapeutics, Inc

Sex: All·Age: 2 - 17

Code: NCT06872125·Phase 3·Recruiting

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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for Cardiovascular Disease

315 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07000357·Phase 3·Recruiting

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Neural Basis of Human Working Memory

for Memory Disorders

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07617506·Recruiting

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Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors

for Childhood Cancer

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06819475·Recruiting

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Engaging Partners in Caring Communities

for Chronic Disease Prevention

1 location in Nashville

Sponsor: Tennessee State University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06932549·Enrolling By Invitation

Quadratus Lumborum Versus Placebo in Open Ventral Hernia Repair

for Hernia, Ventral

1 location in Knoxville

Sponsor: University of Tennessee Graduate School of Medicine

Sex: All·Age: 18+

Code: NCT06953635·Not Yet Recruiting

Team Lifestyle Immersion Hypertension Control Project

for Hypertension

1 location in Nashville

Sponsor: Meharry Medical College

Sex: All·Age: 30 - 80·Accepts healthy volunteers

Code: NCT07201948·Recruiting

Apply to this trial