Clinical Trial Protocol: Alzheimer's Dementia Underlying Encephalopathy

Part of paid clinical trials in Crossville, Tennessee.

Sponsor
Covenant Health, US
Study ID
NCT07222280
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
60 Years - 90 Years
Healthy Volunteers
Not accepted

Interventions

  • Quest AD-Detect blood test — DIAGNOSTIC_TEST
    Blood will be collected and sent for testing using the Quest AD-Detect blood test

Study Details

The goal of this clinical trial is to determine if utilizing the Quest AD-Detect blood test, while patient's are hospitalized for a cognitive diagnosis (such as delirium or encephalopathy), will result in an earlier diagnosis of underlying Alzheimer's disease. * Will this blood test have the ability to distinguish between Alzheimer's disease and other causes of cognitive impairment in the inpatient setting? * Neurology Clinic will complete a 6-month post-hospitalization follow up with patients who have had the Quest AD-Detect Alzheimer's Disease blood test completed while they were inpatient to discuss the risk assessment portfolio

Key Dates

Start date
Jun 10, 2025
Status verified
Oct 2025
Primary completion
Mar 31, 2026
Completion
Mar 31, 2026

Study Design

Enrollment
30 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC

Arms

  • Other: All eligible patients will receive a Quest AD-Detect blood test
    All patients that meet the inclusion criteria, and none of the exclusion criteria, will have their blood tested with the Quest AD-Detect

Primary Outcome Measure

To show the percentage of patients (21 patients in the study) who presented with a cognitive diagnosis (including but not limited to delirium, encephalopathy, etc.) that have a positive biomarker for Alzheimer's dementia [ Time Frame: From enrollment to 6 month follow up appointment with Neurology Clinic. ]

Central Contacts

Locations (6)

FacilityCityStateZIPSite coordinators
Cumberland Medical CenterCrossvilleTennessee38555
Clinical Research Nurse Coordinator
[email protected]
865-331-1337
Samuel A. Moore, MD (PRINCIPAL_INVESTIGATOR)
Roane Medical CenterHarrimanTennessee37748
Clinical Research Nurse Coordinator
[email protected]
865-331-1337
Samuel A. Moore, MD (PRINCIPAL_INVESTIGATOR)
Fort Sanders Regional Medical CenterKnoxvilleTennessee37916
Clinical Research Nurse Coordinator
[email protected]
865-331-1337
Samuel A. Moore, MD (PRINCIPAL_INVESTIGATOR)
Fort Loudon Medical CenterLenoir CityTennessee37772
Clinical Research Nurse Coordinator
[email protected]
865-331-1337
Samuel A. Moore, MD (PRINCIPAL_INVESTIGATOR)
Methodist Medical CenterOak RidgeTennessee37830
Clinical Research Nurse Coordinator
[email protected]
865-331-1337
Samuel A. Moore, MD (PRINCIPAL_INVESTIGATOR)
LeConte Medical CenterSeviervilleTennessee37862
Clinical Research Nurse Coordinator
[email protected]
865-331-1337
Samuel A. Moore, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Crossville, TN

By condition
Alzheimer's disease
By specialty
NeurologyDementia careBrain disordersGeriatrics
By research site
Cumberland Medical Center· Crossville, TNRoane Medical Center· Harriman, TNFort Sanders Regional Medical Center· Knoxville, TNFort Loudon Medical Center· Lenoir City, TNMethodist Medical Center· Oak Ridge, TNLeConte Medical Center· Sevierville, TN

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