Paid Clinical Trials in Tennessee

Tennessee has 2,156 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,156 clinical trials

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Prospective Study to Assess a Diagnostic Aid for Cancer

for Cancer

39 locations incl. Coronado

Sponsor: Harbinger Health

Sex: All·Age: 45+

Code: NCT07046260·Recruiting

Apply to this trial

Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

31 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting

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XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

for Heart Transplant

14 locations incl. La Jolla

Sponsor: XVIVO Perfusion

Sex: All·Age: 18+

Code: NCT06895070·Recruiting

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Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

for AMI Cardiogenic Shock

10 locations incl. Jonesboro

Sponsor: Abiomed Inc.

Sex: All·Age: 18+

Code: NCT06964685·Recruiting

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ELEVATE-HFpEF Clinical Study

for Heart Failure With Preserved Ejection Fraction (HFpEF)

25 locations incl. Phoenix

Sponsor: Medtronic Cardiac Rhythm and Heart Failure

Sex: All·Age: 40+

Code: NCT06678841·Recruiting

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Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer

for Epithelial Ovarian Cancer

7 locations incl. Orlando

Sponsor: Imunon

Sex: Female·Age: 18+

Code: NCT06915025·Phase 3·Recruiting

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Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study

for Migraine

35 locations incl. Flagstaff

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 70

Code: NCT06972056·Phase 4·Recruiting

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AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

for Refractory Rheumatoid Arthritis (RA)

Drug: Rituximab

31 locations incl. Tuscaloosa

Sponsor: Artiva Biotherapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06991114·Phase 2·Recruiting

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Seminar in Unwavering Empowering Presence Optimized for Rehabilitation Teams

for Communication

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07071116·Recruiting

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Feasibility, Safety, and Potential Efficacy of Fecal Microbiota Transplantation (FMT) for Gastrointestinal Dysfunction in Children Following Hematopoietic Cell Transplant (HCT).

for Gastro-Intestinal Disorder

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 22

Code: NCT05664113·Phase 1·Recruiting

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An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

for Metastatic Hormone-sensitive Prostate Cancer

Drug: JSB462

21 locations incl. La Jolla

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT06991556·Phase 2·Recruiting

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PRECIDENTD Engagement Methods for Sites

for Stakeholder Engagement

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: All ages

Code: NCT07053046·Enrolling By Invitation

Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes

for Type 1 Diabetes Mellitus

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06609356·EARLY_Phase 1·Recruiting

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A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

for Castration-Resistant Prostatic Cancer

8 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06863272·Phase 1, Phase 2·Recruiting

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Study With Phage for CF Subjects With Pseudomonas Lung Infection

for Chronic Pseudomonas Aeruginosa Infection

14 locations incl. Birmingham

Sponsor: BiomX Ltd

Sex: All·Age: 18+

Code: NCT06998043·Phase 2·Recruiting

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Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for Alzheimers Disease

68 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 90

Code: NCT07177352·Phase 3·Recruiting

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Multi-Institutional IMPACT Validation

for Facial Injuries

3 locations incl. Sacramento

Sponsor: University of Tennessee

Sex: All·Age: 18+

Code: NCT06850857·Enrolling By Invitation

Effect of Rose Odor Exposure on Ictal Apnea

for Epilepsy

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07116421·EARLY_Phase 1·Recruiting

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Comparison of Two Over the Counter Intravaginal Devices for the Treatment of Stress Urinary Incontinence

for Stress Urinary Incontinence in Women

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 21+

Code: NCT06698627·Enrolling By Invitation

A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer

for Breast Cancer

134 locations incl. Daphne

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06966453·Phase 1, Phase 2·Recruiting

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A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

for Breast Neoplasms

53 locations incl. Gilbert

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06966700·Phase 3·Recruiting

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Efficacy and Safety of IMVT-1402 in Adult Participants With Primary Sjogren's Disease With Moderate to Severe Systemic Disease Activity

for Primary Sjögren's Syndrome

Drug: IMVT-1402

29 locations incl. Covina

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 74

Code: NCT06979531·Phase 2·Recruiting

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E-Mindfulness Approaches for Living After Breast Cancer

for Breast Cancer

332 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18 - 50

Code: NCT06748222·Phase 3·Recruiting

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The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

for Ischemic Heart Disease (IHD)

12 locations incl. San Francisco

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 35 - 85

Code: NCT06854458·Recruiting

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A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

for Heart Failure

29 locations incl. Birmingham

Sponsor: Novo Nordisk A/S

Sex: All·Age: 40 - 84

Code: NCT06979362·Phase 2·Recruiting

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Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Low-grade NMIBC

28 locations incl. Homewood

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06995677·Phase 2·Recruiting

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Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

for Moderate Aortic Valve Stenosis

Drug: Ataciguat

66 locations incl. Birmingham

Sponsor: Kardigan, Inc.

Sex: All·Age: 50+

Code: NCT07001800·Phase 2, Phase 3·Recruiting

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A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Sonelokimab in Participants With Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa

49 locations incl. Birmingham

Sponsor: MoonLake Immunotherapeutics AG

Sex: All·Age: 12+

Code: NCT07007637·Phase 3·Enrolling By Invitation

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for Chronic Obstructive Pulmonary Disease (COPD)

86 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07082738·Phase 2·Recruiting

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Long Term Follow-Up Study for Individuals With Hemoglobin Disorders After Hematopoietic Cell Transplant or Gene Therapy

for Hemoglobin Disorder

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT06646640·Recruiting

Apply to this trial

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

for Ulcerative Colitis

Drug: Tirzepatide

37 locations incl. Dothan

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937086·Phase 3·Recruiting

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Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

for Crohn's Disease

Drug: Tirzepatide

35 locations incl. Dothan

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937099·Phase 3·Recruiting

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Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial Hypertension

for Pulmonary Arterial Hypertension

Drug: Empagliflozin

3 locations incl. Baltimore

Sponsor: Gustavo A Heresi, MD, MS

Sex: All·Age: 18+

Code: NCT06992440·Phase 2·Enrolling By Invitation

A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

for Inflammatory Bowel Disease (IBD)

46 locations incl. Birmingham

Sponsor: Mirador Therapeutics, Inc.

Sex: All·Age: 18 - 80

Code: NCT07113522·Phase 2·Recruiting

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Data Gathering for A10900

for Retinal Disease

4 locations incl. Anaheim

Sponsor: Optos, PLC

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT07149740·Recruiting

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Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

for Heart Failure With Preserved Ejection Fraction

106 locations incl. Birmingham

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07037459·Phase 3·Recruiting

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Safety Study of Viaskin® Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers)

for Allergy

56 locations incl. Birmingham

Sponsor: DBV Technologies

Sex: All·Age: 1 - 3

Code: NCT07003919·Phase 3·Recruiting

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A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

for Pancreatic Ductal Adenocarcinoma

13 locations incl. Los Angeles

Sponsor: Verastem, Inc.

Sex: All·Age: 18+

Code: NCT07020221·Phase 1, Phase 2·Recruiting

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Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

149 locations incl. Gilbert

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06532279·Phase 2·Recruiting

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Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer

for Metastatic Colorectal Adenocarcinoma

Drug: Bevacizumab

13 locations incl. Gainesville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06696768·Phase 1·Recruiting

Apply to this trial